2017
Metabolomics reveals new metabolic perturbations in children with type 1 diabetes
Galderisi A, Pirillo P, Moret V, Stocchero M, Gucciardi A, Perilongo G, Moretti C, Monciotti C, Giordano G, Baraldi E. Metabolomics reveals new metabolic perturbations in children with type 1 diabetes. Pediatric Diabetes 2017, 19: 59-67. PMID: 28401628, DOI: 10.1111/pedi.12524.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCase-Control StudiesChildDiabetes Mellitus, Type 1FemaleHumansMaleMetabolomeMetabolomicsConceptsBody mass indexType 1 diabetesHealthy controlsPubertal statusExcess of cortisolMetabolome of childrenPediatric diabetes clinicMacrovascular complicationsDiabetes clinicDisease durationNeuronal damagePediatric patientsClinical featuresMass indexCase groupTryptophan catabolitesHealthy peersUrinary metabolitesUrinary samplesBacterial productsT1DUntargeted metabolomics approachMetabolic perturbationsDiabetesPatients
2012
Mitochondrial Diabetes in Children: Seek and You Will Find It
Mazzaccara C, Iafusco D, Liguori R, Ferrigno M, Galderisi A, Vitale D, Simonelli F, Landolfo P, Prisco F, Masullo M, Sacchetti L. Mitochondrial Diabetes in Children: Seek and You Will Find It. PLOS ONE 2012, 7: e34956. PMID: 22536343, PMCID: PMC3334935, DOI: 10.1371/journal.pone.0034956.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCase-Control StudiesChildChild, PreschoolDeafnessDiabetes Mellitus, Type 2Electron Transport Complex IElectron Transport Complex IVFemaleGenes, MitochondrialGenetic Association StudiesGenome, MitochondrialHumansMaleMitochondriaMitochondrial DiseasesPedigreeSequence Analysis, DNAConceptsMitochondrial diabetesHitherto unknown associationMaternally Inherited DiabetesDiabetes/Most patientsDiabetic childrenDiabetic adolescentsCeliac diseaseInherited DiabetesComplex syndromeDiabetic phenotypeRare formDiabetesPathogenic significanceMacular dystrophyHearing impairmentPatientsG variantMaculopathyChildrenMothersDiseaseImpairmentDeafnessUnknown association