2023
Screening strategies for glucose tolerance abnormalities and diabetes in people with cystic fibrosis
Weiss L, Reix P, Mosnier-Pudar H, Ronsin O, Beltrand J, Reynaud Q, Mely L, Burgel P, Stremler N, Rakotoarisoa L, Galderisi A, Perge K, Bendelac N, Abely M, Kessler L. Screening strategies for glucose tolerance abnormalities and diabetes in people with cystic fibrosis. Diabetes & Metabolism 2023, 49: 101444. PMID: 37030530, DOI: 10.1016/j.diabet.2023.101444.Peer-Reviewed Original ResearchConceptsGlucose tolerance abnormalitiesCystic fibrosis-related diabetesTolerance abnormalitiesCystic fibrosisAnnual oral glucose tolerance testOral glucose tolerance testGlucose tolerance testLong asymptomatic periodStage of diabetesNew comorbiditiesAsymptomatic periodClinical profileTolerance testNew diagnostic toolsPathophysiological knowledgeDiabetesNutritional outcomesPatientsFibrosisAbnormalitiesScreening strategyLife expectancyDiagnostic toolScreening methodComorbidities
2022
SGLT2i Improves Glycemic Control in Patients With Congenital Severe Insulin Resistance.
Galderisi A, Tamborlane W, Taylor SI, Attia N, Moretti C, Barbetti F. SGLT2i Improves Glycemic Control in Patients With Congenital Severe Insulin Resistance. Pediatrics 2022, 150 PMID: 35652305, DOI: 10.1542/peds.2021-055671.Peer-Reviewed Original ResearchConceptsRabson-Mendenhall syndromeGlycemic controlHemoglobin A1cRenal calcium excretionInsulin-resistant diabetesSevere insulin resistanceCalcium excretionUrinary calciumAntidiabetic treatmentDay doseDose escalationSecond patientFirst patientInsulin levelsInsulin resistanceUrinary excretionSerum glucosePatientsEmpagliflozinMild increaseDapagliflozinΒ-hydroxybutyrateTarget rangeA1CExcretion
2017
Metabolomics reveals new metabolic perturbations in children with type 1 diabetes
Galderisi A, Pirillo P, Moret V, Stocchero M, Gucciardi A, Perilongo G, Moretti C, Monciotti C, Giordano G, Baraldi E. Metabolomics reveals new metabolic perturbations in children with type 1 diabetes. Pediatric Diabetes 2017, 19: 59-67. PMID: 28401628, DOI: 10.1111/pedi.12524.Peer-Reviewed Original ResearchConceptsBody mass indexType 1 diabetesHealthy controlsPubertal statusExcess of cortisolMetabolome of childrenPediatric diabetes clinicMacrovascular complicationsDiabetes clinicDisease durationNeuronal damagePediatric patientsClinical featuresMass indexCase groupTryptophan catabolitesHealthy peersUrinary metabolitesUrinary samplesBacterial productsT1DUntargeted metabolomics approachMetabolic perturbationsDiabetesPatientsA Telemonitoring Service Supporting Preterm Newborns Care in a Neonatal Intensive Care Unit
Losiouk E, Lanzola G, Galderisi A, Trevisanuto D, Steil G, Facchinetti A, Cobelli C. A Telemonitoring Service Supporting Preterm Newborns Care in a Neonatal Intensive Care Unit. 2017, 1-6. DOI: 10.1109/rtsi.2017.8065890.Peer-Reviewed Original ResearchNeonatal intensive care unitIntensive care unitCare unitPreterm newbornsLow birth weight infantsBirth weight infantsGlucose infusion rateDifferent clinical trialsHealth care staffContinuous glucose monitoringWeight infantsHeel prickNewborn careClinical benefitUniversity HospitalClinical trialsInfusion rateCare staffArterial samplingGlucose monitoringWard roomsGlucose dataGlucose concentrationPatientsNewborns
2013
Six cases with severe insulin resistance (SIR) associated with mutations of insulin receptor: Is a Bartter-like syndrome a feature of congenital SIR?
Grasso V, Colombo C, Favalli V, Galderisi A, Rabbone I, Gombos S, Bonora E, Massa O, Meschi F, Cerutti F, Iafusco D, Bonfanti R, Monciotti C, Barbetti F. Six cases with severe insulin resistance (SIR) associated with mutations of insulin receptor: Is a Bartter-like syndrome a feature of congenital SIR? Acta Diabetologica 2013, 50: 951-957. PMID: 23824322, DOI: 10.1007/s00592-013-0490-x.Peer-Reviewed Case Reports and Technical NotesConceptsSevere insulin resistanceRabson-Mendenhall syndromeDonohue syndromePatient 3Insulin resistanceAbsence of hypertensionGene mutationsINSR mutationsInsulin receptor gene mutationsBartter-like syndromeBartter syndrome type IIReceptor gene mutationsYear of birthSevere hirsutismClinical featuresFifth patientPotassium supplementationAcanthosis nigricansHyperreninemic hyperaldosteronismRenal abnormalitiesCongenital syndromePatientsPubertal femalesSyndromeINSR gene
2012
Mitochondrial Diabetes in Children: Seek and You Will Find It
Mazzaccara C, Iafusco D, Liguori R, Ferrigno M, Galderisi A, Vitale D, Simonelli F, Landolfo P, Prisco F, Masullo M, Sacchetti L. Mitochondrial Diabetes in Children: Seek and You Will Find It. PLOS ONE 2012, 7: e34956. PMID: 22536343, PMCID: PMC3334935, DOI: 10.1371/journal.pone.0034956.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCase-Control StudiesChildChild, PreschoolDeafnessDiabetes Mellitus, Type 2Electron Transport Complex IElectron Transport Complex IVFemaleGenes, MitochondrialGenetic Association StudiesGenome, MitochondrialHumansMaleMitochondriaMitochondrial DiseasesPedigreeSequence Analysis, DNAConceptsMitochondrial diabetesHitherto unknown associationMaternally Inherited DiabetesDiabetes/Most patientsDiabetic childrenDiabetic adolescentsCeliac diseaseInherited DiabetesComplex syndromeDiabetic phenotypeRare formDiabetesPathogenic significanceMacular dystrophyHearing impairmentPatientsG variantMaculopathyChildrenMothersDiseaseImpairmentDeafnessUnknown association
2011
Chat Line for Adolescents with Type 1 Diabetes: A Useful Tool to Improve Coping with Diabetes: A 2-Year Follow-Up Study
Iafusco D, Galderisi A, Nocerino I, Cocca A, Zuccotti G, Prisco F, Scaramuzza A. Chat Line for Adolescents with Type 1 Diabetes: A Useful Tool to Improve Coping with Diabetes: A 2-Year Follow-Up Study. Diabetes Technology & Therapeutics 2011, 13: 551-555. PMID: 21406010, DOI: 10.1089/dia.2010.0188.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAdolescent BehaviorAttitude to HealthChildChild BehaviorDiabetes Mellitus, Type 1FemaleFollow-Up StudiesGlycated HemoglobinHealth BehaviorHumansInternetItalyMalePatient CompliancePatient Education as TopicQuality of LifeReproducibility of ResultsSelf CareSurveys and Questionnaires