2022
Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study
Galderisi A, Tordin M, Suppiej A, Cainelli E, Baraldi E, Trevisanuto D. Glucose-to-lactate ratio and neurodevelopment in infants with hypoxic-ischemic encephalopathy: an observational study. European Journal Of Pediatrics 2022, 182: 837-844. PMID: 36484862, PMCID: PMC9899169, DOI: 10.1007/s00431-022-04694-3.Peer-Reviewed Original ResearchConceptsHypoxic-ischemic encephalopathyTherapeutic hypothermiaNeurodevelopmental outcomesLactate ratioDay 1Severe hypoxic-ischemic encephalopathyNew risk markerSevere hypoNeonatal hypoglycemiaMetabolic outcomesRisk markersObservational studyMetabolic variablesDay 2InfantsLactate concentrationEncephalopathyLactate kineticsNeurodevelopmentMetabolic fuelsNeonatesStrongest predictorHypothermiaOutcomesGlucoseNeonatal Hyperglycemia and Neurodevelopmental Outcomes in Preterm Infants: A Review
Guiducci S, Meggiolaro L, Righetto A, Piccoli M, Baraldi E, Galderisi A. Neonatal Hyperglycemia and Neurodevelopmental Outcomes in Preterm Infants: A Review. Children 2022, 9: 1541. PMID: 36291477, PMCID: PMC9600957, DOI: 10.3390/children9101541.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGriffiths Mental Developmental ScalesInternational trial registriesPreterm infantsNeonatal hyperglycemiaYears of lifeNeurodevelopmental outcomesEarly neonatal hyperglycemiaCochrane Central RegisterLong-term neurodevelopmentQuality of evidenceEffects of hyperglycemiaMovement Assessment BatteryGlucose impairmentCentral RegisterControlled TrialsNeurodevelopment outcomeTrials RegistryCochrane LibraryNeurodevelopment assessmentNeurological delayMotor functionCurrent evidencePRISMA guidelinesHyperglycemiaBayley Scales
2021
Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants
Galderisi A, Trevisanuto D, Russo C, Hall R, Bruschettini M. Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants. 2021, 2021: cd013309. PMID: 34931697, PMCID: PMC8690212, DOI: 10.1002/14651858.cd013309.pub3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsRisk of hypoglycaemiaUse of CGMContinuous glucose monitoringPreterm infantsIntermittent modalitiesRisk ratioEffects of CGMLong-term neurodevelopmental impairmentGlucose monitoringEfficacy of CGMCare Group (EPOC) criteriaPreterm infants 1Cochrane Effective PracticePrevention of morbidityClinical trials databasesLong-term outcomesConfidence intervalsPreterm infant mortalitySafety of CGMImprecision of estimatesFixed-effects modelAdverse neurodevelopmentGRADE approachNeurodevelopmental outcomesDATA COLLECTION