2021
Metabolic syndrome and insulin resistance in pre-pubertal children with psoriasis
Caroppo F, Galderisi A, Ventura L, Belloni Fortina A. Metabolic syndrome and insulin resistance in pre-pubertal children with psoriasis. European Journal Of Pediatrics 2021, 180: 1739-1745. PMID: 33483797, PMCID: PMC8105196, DOI: 10.1007/s00431-020-03924-w.Peer-Reviewed Original ResearchConceptsPre-pubertal childrenMetabolic syndromeInsulin resistanceMetabolic diseasesMetabolic syndrome risk factorsSingle-center prospective studyHomeostatic model assessmentAge-specific percentilesCardiometabolic comorbiditiesChildhood psoriasisProspective studyRisk factorsHigh prevalencePsoriasisModel assessmentSyndromePrevalenceLimited dataYoung childrenChildrenAdultsDiseaseComorbiditiesHOMADiagnosis
2016
High frequency of diabetic ketoacidosis at diagnosis of type 1 diabetes in Italian children: a nationwide longitudinal study, 2004–2013
Cherubini V, Skrami E, Ferrito L, Zucchini S, Scaramuzza A, Bonfanti R, Buono P, Cardella F, Cauvin V, Chiari G, d′Annunzio G, Frongia A, Iafusco D, Patera I, Toni S, Tumini S, Rabbone I, Lombardo F, Carle F, Gesuita R, Lera R, De Luna L, Gualtieri A, Zecchino C, Piccinno E, Reinstadler P, Prandi E, Gallo F, Morganti G, Ripoli C, La Loggia A, Scanu P, Cardinale G, Tomaselli L, Citriniti F, Lazzaro N, De Donno V, Mainetti B, Coccioli M, Maccioni R, Marongiu U, Bruzzese M, Iannilli A, Pardi D, Confetto S, Zanfardino A, Iughetti L, Franzese A, Cadario F, Milia A, Piredda G, Soro M, Correddu A, Galderisi A, De Berardinis F, Federico G, Zanette G, Suprani T, Pedini A, Bitti M, Delvecchio M, Trada M, Meloni G, Gaiero A, Bulciolu P, Guerraggio L, Faleschini E, Zanatta M, Salvatoni A, Maffeis C, Arnaldi C. High frequency of diabetic ketoacidosis at diagnosis of type 1 diabetes in Italian children: a nationwide longitudinal study, 2004–2013. Scientific Reports 2016, 6: 38844. PMID: 27991500, PMCID: PMC5171855, DOI: 10.1038/srep38844.Peer-Reviewed Original ResearchConceptsSevere diabetic ketoacidosisDiabetic ketoacidosisType 1 diabetesDKA frequencyAge groupsLongitudinal population-based studyType 1 diabetes diagnosisMultiple logistic regression modelPopulation-based studyNationwide longitudinal studyYears of ageLogistic regression modelsItalian childrenFamily historyHigh riskMild/Diabetes diagnosisKetoacidosisHealthcare strategiesYoung age childrenDiabetesEarly detectionDiagnosisLongitudinal studyTime trends
2012
Emerging Effects of Early Environmental Factors over Genetic Background for Type 1 Diabetes Susceptibility: Evidence from a Nationwide Italian Twin Study
Nisticò L, Iafusco D, Galderisi A, Fagnani C, Cotichini R, Toccaceli V, Stazi M, Endocrinology and Diabetology T. Emerging Effects of Early Environmental Factors over Genetic Background for Type 1 Diabetes Susceptibility: Evidence from a Nationwide Italian Twin Study. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: e1483-e1491. PMID: 22569240, DOI: 10.1210/jc.2011-3457.Peer-Reviewed Original ResearchConceptsProband-wise concordanceType 1 diabetes susceptibilityDiabetic twinsDiabetes susceptibilityRecurrence riskPediatric diabetes care centersRecent onset casesDiabetes care centerKaplan-Meier methodZinc transporter 8Type 1 diabetesEarly postnatal lifeEarly environmental factorsMean ageCare centerDiabetes recordsProband diagnosisPostnatal lifeTransporter 8Twin cohortType 1Median yearsDiagnosisTwin RegistryDizygotic pairs