2022
The Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain A Meta-Analysis
Agha AM, Pacor J, Grandhi GR, Mszar R, Khan SU, Parikh R, Agrawal T, Burt J, Blankstein R, Blaha MJ, Shaw LJ, Al-Mallah MH, Brackett A, Cainzos-Achirica M, Miller EJ, Nasir K. The Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain A Meta-Analysis. JACC Cardiovascular Imaging 2022, 15: 1745-1757. PMID: 36202453, DOI: 10.1016/j.jcmg.2022.03.031.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseAcute chest painCoronary artery calciumCoronary artery diseaseStable chest painNonobstructive coronary artery diseaseMajor adverse cardiac eventsAdverse cardiac eventsChest painCardiac eventsLow prevalenceAbsence of CACHealth care delivery modelsCare delivery modelsA Meta-AnalysisNegative predictive valueCAC assessmentArtery calciumCAC scoreIntermediate riskArtery diseaseCoronary CTACTA assessmentPrognostic valueTomography angiography
2020
Mortality risk associated with venous thromboembolism: a systematic review and Bayesian meta-analysis
Klemen ND, Feingold PL, Hashimoto B, Wang M, Kleyman S, Brackett A, Gross CP, Pei KY. Mortality risk associated with venous thromboembolism: a systematic review and Bayesian meta-analysis. The Lancet Haematology 2020, 7: e583-e593. PMID: 32735837, DOI: 10.1016/s2352-3026(20)30211-8.Peer-Reviewed Original ResearchConceptsVenous thromboembolism preventionFatal pulmonary embolismPulmonary embolismVenous thromboembolismThromboembolism preventionMajor bleedingRisk ratioMortality riskTreatment groupsControl groupSystematic reviewLess major bleedingMedian risk ratioMore pulmonary embolismDe-escalation trialsVenous thromboembolism riskStudy of patientsActive control agentWeb of ScienceAntiplatelet therapyEligible RCTsPrimary endpointSecondary endpointsComposite endpointOverall mortality