2021
Laboratory evaluation and prognostication among adults and children with CEBPA‐mutant acute myeloid leukemia
Mendoza H, Podoltsev NA, Siddon AJ. Laboratory evaluation and prognostication among adults and children with CEBPA‐mutant acute myeloid leukemia. International Journal Of Laboratory Hematology 2021, 43: 86-95. PMID: 34288448, DOI: 10.1111/ijlh.13517.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCEBPA mutant acute myeloid leukemiaAcute myeloid leukemiaCEBPA mutationsMyeloid leukemiaLeukemogenic mutationsPositive prognostic impactSingle CEBPA mutationsSimilar survival outcomesNegative prognostic effectFLT3-ITD mutationLaboratory evaluationWild-type CEBPAMultiparameter flow cytometryGermline CEBPA mutationsFavorable prognosisPrognostic impactMutation presencePrognostic effectRisk stratificationSurvival outcomesGATA2 mutationsDistinct subtypesMolecular findingsCEBPA geneFlow cytometry
2012
Human herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma
Siddon A, Lozovatsky L, Mohamed A, Hudnall SD. Human herpesvirus 6 positive Reed–Sternberg cells in nodular sclerosis Hodgkin lymphoma. British Journal Of Haematology 2012, 158: 635-643. PMID: 22757777, DOI: 10.1111/j.1365-2141.2012.09206.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedBlotting, WesternCell Line, TumorDNA, ViralEpstein-Barr Virus InfectionsFemaleHerpesvirus 4, HumanHerpesvirus 6, HumanHodgkin DiseaseHumansImmunohistochemistryLymphoma, FollicularMaleMiddle AgedPolymerase Chain ReactionReed-Sternberg CellsRoseolovirus InfectionsSclerosisYoung AdultConceptsNodular sclerosis Hodgkin lymphomaNodular sclerosis HLHHV-6 DNAEpstein-Barr virusHHV-6Hodgkin's lymphomaReed-Sternberg cellsPolymerase chain reactionRS cellsNSHL casesEBV-negative diseaseReactive lymphoid hyperplasiaClassical Hodgkin lymphomaBi-modal age distributionHHV-6 genomeYounger patientsInfectious etiologyLymphoid hyperplasiaPCR positivityYounger ageImmunohistochemistryMost casesConflicting resultsChain reactionCD30