2017
The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry
Lipovsky A, Erden A, Kanaya E, Zhang W, Crite M, Bradfield C, MacMicking J, DiMaio D, Schoggins JW, Iwasaki A. The cellular endosomal protein stannin inhibits intracellular trafficking of human papillomavirus during virus entry. Journal Of General Virology 2017, 98: 2821-2836. PMID: 29058661, PMCID: PMC5845663, DOI: 10.1099/jgv.0.000954.Peer-Reviewed Original ResearchConceptsHuman papillomavirusEntry of HPVVirus entryImportant infectious causeL1 major capsid proteinHPV typesTrans-Golgi networkInfectious causesProphylactic vaccinesHPV16 infectionL2 minor capsid proteinHPV entryDeadly cancerHPV16 entryBasal levelsInfectionVirus uptakeRetrograde transportHuman keratinocytesCapsid proteinHPV16PapillomavirusVirus uncoatingNon-enveloped virusesVirus
2014
Application of the Proximity-Dependent Assay and Fluorescence Imaging Approaches to Study Viral Entry Pathways
Lipovsky A, Zhang W, Iwasaki A, DiMaio D. Application of the Proximity-Dependent Assay and Fluorescence Imaging Approaches to Study Viral Entry Pathways. Methods In Molecular Biology 2014, 1270: 437-451. PMID: 25702134, DOI: 10.1007/978-1-4939-2309-0_30.Peer-Reviewed Original ResearchConceptsGenome-wide RNA interference screenEnriched gene categoriesConfirmation of phenotypesGenome-wide lossRNA interference screenVirus entryFunction genetic screenRNA interference studiesFluorescence imaging approachesProximity ligation assayGenetic screenGene categoriesInterference screenMembrane compartmentsIndividual genesBiochemical approachesCellular compartmentsMolecular intricaciesMicroscopy-based methodBioinformatics analysisProtein locationRNA interferenceCellular organellesViral entry pathwayCellular factors