2018
Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species
Ayaz A, Agarwal A, Sharma R, Kothandaraman N, Cakar Z, Sikka S. Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species. Andrologia 2018, 50: e13015. PMID: 29656391, DOI: 10.1111/and.13015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmyloid beta-Protein PrecursorAntigens, NeoplasmF-Box ProteinsHSP70 Heat-Shock ProteinsHumansInfertility, MaleMaleMAP Kinase Kinase Kinase 3Nerve Tissue ProteinsNitric Oxide Synthase Type IIPeptidyl-Dipeptidase AProteomicsReactive Oxygen SpeciesRibosomal ProteinsSmall Ubiquitin-Related Modifier ProteinsSpermatozoaTestisUbiquitinsConceptsReactive oxygen speciesSperm proteinsMale infertilityAngiotensin-converting enzymePost-acrosomal regionPoor sperm qualityLevels of reactive oxygen speciesSperm qualityTesticular environmentInfertile menHeat shock proteinsProteomic analysisHSPA2SpermatozoaExpression profilesOxidative stressRPS27aProteinOxygen speciesMAP3K3Western blottingNeck areaRisk factorsUBL4ASperm
2016
Post-Translational Modifications in sperm Proteome: The Chemistry of Proteome diversifications in the Pathophysiology of male factor infertility
Samanta L, Swain N, Ayaz A, Venugopal V, Agarwal A. Post-Translational Modifications in sperm Proteome: The Chemistry of Proteome diversifications in the Pathophysiology of male factor infertility. Biochimica Et Biophysica Acta 2016, 1860: 1450-1465. PMID: 27062907, DOI: 10.1016/j.bbagen.2016.04.001.Peer-Reviewed Original ResearchConceptsPost-translational modificationsSperm proteinsSperm functionOccurrence of post-translational modificationsExpressed protein complementHuman sperm proteinsProtein synthesis machineryAnalysis of post-translational modificationsComplex interaction networksProteome diversificationSperm proteomeFemale reproductive tractHuman spermatozoaProtein complementStructure-function relationshipsSynthesis machineryInteraction networkProtein stabilityMale infertilitySpermMale factor infertilitySpermatozoaProtein profilesDifferential occurrenceFertility potential
2015
Comparative proteomic pathway analysis of different phenotypes of ejaculated spermatozoa in fertile and infertile men
Agarwal A, Cui Z, Sharma R, Samanta L, Gupta S, Ayaz A, Sabanegh E. Comparative proteomic pathway analysis of different phenotypes of ejaculated spermatozoa in fertile and infertile men. Fertility And Sterility 2015, 104: e297-e298. DOI: 10.1016/j.fertnstert.2015.07.931.Peer-Reviewed Original Research
2014
MP66-05 OXIDATIVE STRESS PROTEINS IDENTIFIED IN HUMAN SPERMATOZOA BY PROTEOMIC AND BIOINFORMATIC ANALYSIS
Sharma R, Agarwal A, Durairajanayagam D, Cui Z, Ayaz A, Sabanegh E. MP66-05 OXIDATIVE STRESS PROTEINS IDENTIFIED IN HUMAN SPERMATOZOA BY PROTEOMIC AND BIOINFORMATIC ANALYSIS. Journal Of Urology 2014, 191: e742. DOI: 10.1016/j.juro.2014.02.2052.Peer-Reviewed Original Research