2019
The Impact of Single and Multiple Sperm Abnormalities and Low-Level Leukocytospermia on Sperm DNA
Alshahrani S, Ahmad G, Khan H, Ayaz A, Ali A. The Impact of Single and Multiple Sperm Abnormalities and Low-Level Leukocytospermia on Sperm DNA. Journal Of Men's Health 2019, 15: e51-e58. DOI: 10.22374/jomh.v15i2.144.Peer-Reviewed Original ResearchStandard sperm parametersSperm parametersDNA damageAnalysis of semen characteristicsCohort of infertile menSperm DNA testingSperm DNA damageDNA fragmentation analysisLevel of leukocytospermiaNick end labelingSperm motilityInfertile menSemen characteristicsSpermSperm abnormalitiesSperm DNASemen abnormalitiesPercentage of DNA damageRetrospective analysisFragment analysisDNAAbnormal parametersART treatmentEnd labelingDNA testing
2015
Major protein alterations in spermatozoa from infertile men with unilateral varicocele
Agarwal A, Sharma R, Durairajanayagam D, Ayaz A, Cui Z, Willard B, Gopalan B, Sabanegh E. Major protein alterations in spermatozoa from infertile men with unilateral varicocele. Reproductive Biology And Endocrinology 2015, 13: 8. PMID: 25890347, PMCID: PMC4383193, DOI: 10.1186/s12958-015-0007-2.Peer-Reviewed Original ResearchConceptsInfertile menVaricocele groupLTQ-Orbitrap Elite hybrid mass spectrometer systemAcquisition of sperm motilityPost-translational modification proteinsFertile groupCause of male factor infertilitySmall molecule biochemistryAcrosome reactionSperm maturationUnilateral varicoceleFunctional annotationModification proteinsReactive oxygen species levelsSperm motilityResultsSperm concentrationBioinformatics toolsSpecies levelFertile menSignal transductionProteomic changesFunctional pathwaysBioinformatics analysisAnalyzed proteinsGene expression