2018
Chapter 23 Standardized Semen Analysis and Quality Control Management for Multicenter Male Reproductive Toxicology Clinical Trials
Sikka S, Ayaz A. Chapter 23 Standardized Semen Analysis and Quality Control Management for Multicenter Male Reproductive Toxicology Clinical Trials. 2018, 371-386. DOI: 10.1016/b978-0-12-801299-4.00023-2.Peer-Reviewed Original ResearchSemen analysisReproductive failureVariable predictive valueIncidence of reproductive failureHormonal evaluationMen's reproductive healthExposure to endocrine-disrupting chemicalsSemen samplesClinical trialsIncreased incidencePredictive valueLaboratory evaluationReproductive healthTobacco smokeFood additivesNonstandardized techniqueReproductive endocrinologyToxicity trialsSemenStress factorsControl managementEndocrine-disrupting chemicalsLack of standardizationGenetic issuesCounting chamber
2014
Infertile men older than 40 years are at higher risk of sperm DNA damage
Alshahrani S, Agarwal A, Assidi M, Abuzenadah A, Durairajanayagam D, Ayaz A, Sharma R, Sabanegh E. Infertile men older than 40 years are at higher risk of sperm DNA damage. Reproductive Biology And Endocrinology 2014, 12: 103. PMID: 25410314, PMCID: PMC4258051, DOI: 10.1186/1477-7827-12-103.Peer-Reviewed Original ResearchConceptsSperm DNA damageRisk of sperm DNA damageInfertile menReactive oxygen speciesDNA damagePercentage of sperm DNA fragmentationLevels of sperm DNA damageSemen analysisSeminal reactive oxygen speciesPaternal ageSperm DNA fragmentationAge groupsAssociated with higher riskPaternal age >DNA fragmentationSperm parametersAdvanced paternal ageSemen parametersSemen qualityEffect of paternal ageSpermRetrospective studyGroup BMethodsA totalGroup A