2015
Genetic Diversity and Population Structure of Trypanosoma brucei in Uganda: Implications for the Epidemiology of Sleeping Sickness and Nagana
Echodu R, Sistrom M, Bateta R, Murilla G, Okedi L, Aksoy S, Enyioha C, Enyaru J, Opiyo E, Gibson W, Caccone A. Genetic Diversity and Population Structure of Trypanosoma brucei in Uganda: Implications for the Epidemiology of Sleeping Sickness and Nagana. PLOS Neglected Tropical Diseases 2015, 9: e0003353. PMID: 25695634, PMCID: PMC4335064, DOI: 10.1371/journal.pntd.0003353.Peer-Reviewed Original Research
2011
Estimation of the Human Blood Index in Malaria Mosquito Vectors in Equatorial Guinea after Indoor Antivector Interventions
Pappa V, Reddy M, Overgaard H, Abaga S, Caccone A. Estimation of the Human Blood Index in Malaria Mosquito Vectors in Equatorial Guinea after Indoor Antivector Interventions. American Journal Of Tropical Medicine And Hygiene 2011, 84: 298-301. PMID: 21292902, PMCID: PMC3029185, DOI: 10.4269/ajtmh.2011.10-0463.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnophelesBloodCulicidaeEquatorial GuineaFeeding BehaviorHousingHumansInsect VectorsInsecticidesMalariaMosquito ControlPolymerase Chain Reaction
2010
Genetic Differentiation between Marine Iguanas from Different Breeding Sites on the Island of Santa Fé (Galápagos Archipelago)
Lanterbecq D, Glaberman S, Vitousek M, Steinfartz S, Benavides E, Wikelski M, Caccone A. Genetic Differentiation between Marine Iguanas from Different Breeding Sites on the Island of Santa Fé (Galápagos Archipelago). Journal Of Heredity 2010, 101: 663-675. PMID: 20538757, DOI: 10.1093/jhered/esq067.Peer-Reviewed Original ResearchConceptsMarine iguanasGenetic diversitySex-biased dispersalMitochondrial control regionMitochondrial DNA markersGalápagos marine iguanasSanta FéDifferent breeding sitesSouthern sitesGenetic differentiationEvolutionary signalGenetic structureMicrosatellite lociDNA markersControl regionGenetic variationGenetic patternsBreeding sitesLittle differentiationBase pairsNeighboring islandsIguanasDiversitySampling sitesDifferentiationAnopheles Immune Genes and Amino Acid Sites Evolving Under the Effect of Positive Selection
Parmakelis A, Moustaka M, Poulakakis N, Louis C, Slotman MA, Marshall JC, Awono-Ambene PH, Antonio-Nkondjio C, Simard F, Caccone A, Powell JR. Anopheles Immune Genes and Amino Acid Sites Evolving Under the Effect of Positive Selection. PLOS ONE 2010, 5: e8885. PMID: 20126662, PMCID: PMC2811201, DOI: 10.1371/journal.pone.0008885.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsAnophelesBase SequenceDNA PrimersGenetic VariationImmunityPhylogenyPolymerase Chain ReactionPolymorphism, GeneticRecombination, GeneticSelection, GeneticConceptsPositive selectionImmune genesGambiae complexDN/dS ratiosLineage-specific evolutionPopulation genetics frameworkAmino acid sitesAnopheles gambiae complexSpecific amino acidsInnate immunity genesAncestral polymorphismComparative phylogeneticsGene diversityEvolutionary historyNatural populationsGenetic diversityGenetic frameworkNatural selectionImmunity genesVector biologyDS ratiosGenesAmino acidsDiversityGenetic knowledge
2008
Distribution of knock-down resistance mutations in Anopheles gambiae molecular forms in west and west-central Africa
Santolamazza F, Calzetta M, Etang J, Barrese E, Dia I, Caccone A, Donnelly M, Petrarca V, Simard F, Pinto J, della Torre A. Distribution of knock-down resistance mutations in Anopheles gambiae molecular forms in west and west-central Africa. Malaria Journal 2008, 7: 74. PMID: 18445265, PMCID: PMC2405802, DOI: 10.1186/1475-2875-7-74.Peer-Reviewed Original ResearchMeSH KeywordsAfrica, CentralAfrica, WesternAllelesAnimalsAnophelesDDTGene FrequencyGenotypeInsect VectorsInsecticide ResistanceMutationPolymerase Chain ReactionPyrethrinsConceptsL1014F alleleVoltage-gated sodium channel geneM-form populationsSodium channel geneResistance allele frequencyAnopheles gambiae sensu strictoPhenotypic effectsGambiae sensu strictoSelection pressureGambiae ML1014F mutationMolecular formsPosition 1014Channel genesL1014S mutationS formLigation assayL1014S alleleSensu strictoKdr genotypesVector speciesKdr alleleAllele-specific PCRPoint mutationsFormer mutationHistorical analysis of a near disaster: Anopheles gambiae in Brazil.
Parmakelis A, Russello MA, Caccone A, Marcondes CB, Costa J, Forattini OP, Sallum MA, Wilkerson RC, Powell JR. Historical analysis of a near disaster: Anopheles gambiae in Brazil. American Journal Of Tropical Medicine And Hygiene 2008, 78: 176-8. PMID: 18187802, DOI: 10.4269/ajtmh.2008.78.176.Peer-Reviewed Original ResearchConceptsHuman-mediated range expansionIntrinsic historical interestAnopheles gambiaeDisease vectorsHistorical DNA analysisHuman-mediated dispersalInsect disease vectorsMuseum collectionsHistorical analysisNear disasterHistorical interestAnopheles gambiae complexHistorical informationTime of invasionIntercontinental introductionSpecies complexSpecies identityRange expansionMuseum specimensGambiae complexGambiaeSpeciesAnopheles arabiensisIdentityDNA analysis
2006
Ancient DNA forces reconsideration of evolutionary history of Mediterranean pygmy elephantids
Poulakakis N, Parmakelis A, Lymberakis P, Mylonas M, Zouros E, Reese D, Glaberman S, Caccone A. Ancient DNA forces reconsideration of evolutionary history of Mediterranean pygmy elephantids. Biology Letters 2006, 2: 451-454. PMID: 17148428, PMCID: PMC1686204, DOI: 10.1098/rsbl.2006.0467.Peer-Reviewed Original ResearchConceptsEvolutionary historyDNA sequencesAncient DNA studiesDNA fragmentsMultiple displacement amplification (MDA) methodPygmy mammothsIndependent historyShort DNA sequencesB-DNA fragmentEastern MediterraneanMediterranean islandsPhylogenetic analysisMolecular dataMainland samplesCretan sampleDNA studiesHistoryElephantidsDiagnostic sitesElephasPrevailing viewIslandsMammothsMammuthusSequenceCo‐occurrence of East and West African kdr mutations suggests high levels of resistance to pyrethroid insecticides in Anopheles gambiae from Libreville, Gabon
Pinto J, Lynd A, Elissa N, Donnelly M, Costa C, Gentile G, Caccone A, DO Rosário V. Co‐occurrence of East and West African kdr mutations suggests high levels of resistance to pyrethroid insecticides in Anopheles gambiae from Libreville, Gabon. Medical And Veterinary Entomology 2006, 20: 27-32. PMID: 16608487, DOI: 10.1111/j.1365-2915.2006.00611.x.Peer-Reviewed Original Research
2004
Variation in an intron sequence of the voltage‐gated sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms
Gentile G, Santolamazza F, Fanello C, Petrarca V, Caccone A, Della Torre A. Variation in an intron sequence of the voltage‐gated sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms. Insect Molecular Biology 2004, 13: 371-377. PMID: 15271209, DOI: 10.1111/j.0962-1075.2004.00494.x.Peer-Reviewed Original ResearchConceptsVoltage-gated sodium channel geneSodium channel geneGenetic differentiationGenetic variationChannel genesPossible selective sweepMajor haplotypesSingle mutational stepAnopheles gambiae MRDNA sitesGene flowSelective sweepsMutational stepsTaxonomic statusIntron sequencesGambiae MMolecular formsIntron ISingle localityIntronic regionsAnopheles gambiae s.Additional haplotypesGambiae s.HaplotypesGenesShort report: A new polymerase chain reaction-restriction fragment length polymorphism method to identify Anopheles arabiensis from An. gambiae and its two molecular forms from degraded DNA templates or museum samples.
Santolamazza F, Della Torre A, Caccone A. Short report: A new polymerase chain reaction-restriction fragment length polymorphism method to identify Anopheles arabiensis from An. gambiae and its two molecular forms from degraded DNA templates or museum samples. American Journal Of Tropical Medicine And Hygiene 2004, 70: 604-6. PMID: 15210999, DOI: 10.4269/ajtmh.2004.70.604.Peer-Reviewed Original Research