2010
Anopheles Immune Genes and Amino Acid Sites Evolving Under the Effect of Positive Selection
Parmakelis A, Moustaka M, Poulakakis N, Louis C, Slotman MA, Marshall JC, Awono-Ambene PH, Antonio-Nkondjio C, Simard F, Caccone A, Powell JR. Anopheles Immune Genes and Amino Acid Sites Evolving Under the Effect of Positive Selection. PLOS ONE 2010, 5: e8885. PMID: 20126662, PMCID: PMC2811201, DOI: 10.1371/journal.pone.0008885.Peer-Reviewed Original ResearchConceptsPositive selectionImmune genesGambiae complexDN/dS ratiosLineage-specific evolutionPopulation genetics frameworkAmino acid sitesAnopheles gambiae complexSpecific amino acidsInnate immunity genesAncestral polymorphismComparative phylogeneticsGene diversityEvolutionary historyNatural populationsGenetic diversityGenetic frameworkNatural selectionImmunity genesVector biologyDS ratiosGenesAmino acidsDiversityGenetic knowledge
2008
Historical DNA analysis reveals living descendants of an extinct species of Galápagos tortoise
Poulakakis N, Glaberman S, Russello M, Beheregaray LB, Ciofi C, Powell JR, Caccone A. Historical DNA analysis reveals living descendants of an extinct species of Galápagos tortoise. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 15464-15469. PMID: 18809928, PMCID: PMC2563078, DOI: 10.1073/pnas.0805340105.Peer-Reviewed Original ResearchConceptsMuseum specimensHistorical DNA analysisDiversification of organismsCaptive breeding programsIsland of FloreanaModern DNA techniquesMicrosatellite dataGalápagos tortoisesConservation biologyMitochondrial DNANatural selectionExtinct speciesExtinct taxaBreeding programsGiant tortoisesIntense harvestingGenetic analysisGenetic dataGalápagos ArchipelagoTortoise populationsDNA techniquesHuman exploitationNearby islandsEnough individualsSpeciesSpecies-specific evolution of class I MHC genes in iguanas (Order: Squamata; Subfamily: Iguaninae)
Glaberman S, Caccone A. Species-specific evolution of class I MHC genes in iguanas (Order: Squamata; Subfamily: Iguaninae). Immunogenetics 2008, 60: 371-382. PMID: 18488213, DOI: 10.1007/s00251-008-0298-y.Peer-Reviewed Original ResearchConceptsMarine iguanasSpecies-specific evolutionGalápagos land iguanasGalápagos marine iguanasDifferent phylogenetic historiesNon-avian reptilesSpecies-specific mannerClass I MHC genesMajor histocompatibility complexConservation geneticsPhylogenetic historySquamate speciesVertebrate taxaDiversified orderGenetic diversityNatural selectionMHC researchDNA dataGenetic basisLand iguanasMultiple lociMHC genesMHC studiesHost resistanceIguanas