2022
Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI)
Demuyakor A, Hu S, Koniaeva E, Liu M, Weng Z, Zhao C, Feng X, He L, Xu Y, Zeng M, Meng W, Sun Y, Yi B, Gao Z, Qin Y, Jia H, Mintz G, Yu B. Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI). BMC Cardiovascular Disorders 2022, 22: 103. PMID: 35287572, PMCID: PMC8922875, DOI: 10.1186/s12872-022-02551-7.Peer-Reviewed Original ResearchConceptsAcute coronary syndromePercutaneous coronary interventionPrimary percutaneous coronary interventionCalcification groupOptical coherence tomographyNodular calcificationStent under-expansionCoronary interventionCoronary syndromeLower left ventricular ejection fractionPresence of nodular calcificationTreated with primary percutaneous coronary interventionUnder-expansionCulprit plaquesVentricular ejection fractionMinimum stent areaEjection fractionProtruding massCoherence tomographyWell-delineated borderPatientsStent areaCalcificationImpact outcomesSignal attenuation
2021
Predictors of non-stenting strategy for acute coronary syndrome caused by plaque erosion: four-year outcomes of the EROSION study.
He L, Qin Y, Xu Y, Hu S, Wang Y, Zeng M, Feng X, Liu Q, Syed I, Demuyakor A, Zhao C, Chen X, Li Z, Meng W, Xu M, Liu H, Ma L, Dai J, Xing L, Yu H, Hou J, Jia H, Mintz G, Yu B. Predictors of non-stenting strategy for acute coronary syndrome caused by plaque erosion: four-year outcomes of the EROSION study. EuroIntervention 2021, 17: 497-505. PMID: 33164894, PMCID: PMC9724919, DOI: 10.4244/eij-d-20-00299.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeNon-TLR groupLong-term prognosisOptical coherence tomographyFollow-upAntithrombotic therapyCoronary syndromePredictor of long-term prognosisResponse to antithrombotic therapyTreated with antithrombotic therapyPlaque erosionLong-term follow-upTarget lesion revascularisationMedian durationPrimary endpointAntithrombotic strategiesOne-month follow-upThrombus reductionGastrointestinal bleedingAngiographic resultsCoherence tomographyStent implantationDiameter stenosisClinic visitsPatients
2018
Does spotty calcification attenuate the response of nonculprit plaque to statin therapy?: A serial optical coherence tomography study
Afolabi A, Mustafina I, Zhao L, Li L, Sun R, Hu S, Zhang S, Jia H, Guilio G, Yu B. Does spotty calcification attenuate the response of nonculprit plaque to statin therapy?: A serial optical coherence tomography study. Catheterization And Cardiovascular Interventions 2018, 91: 582-590. PMID: 29359491, DOI: 10.1002/ccd.27496.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary AngiographyCoronary Artery DiseaseCoronary VesselsFemaleFibrosisHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPlaque, AtheroscleroticPredictive Value of TestsRandomized Controlled Trials as TopicTime FactorsTomography, Optical CoherenceTreatment OutcomeVascular CalcificationConceptsStatin therapyOptical coherence tomographyFibrous cap thicknessSpotty calcificationIntensity statinsModerate statin therapyPresence of spotty calcificationBaseline to 6Lipid-rich plaquesModerate statinsLipid arcCalcification groupCoherence tomographyStatinsTherapyPlaque characteristicsPlaque stabilityCalcificationPlaque progressionMonthsPlaquePatientsVulnerable plaquesMarkers of vulnerable plaqueBaseline
2017
Impact of statins therapy on morphological changes in lipid-rich plaques stratified by 10-Year framingham risk score: A serial optical coherence tomography study
Zhu Y, Lin L, Wang C, Jia H, Hu S, Li L, Zhang X, Zheng G, Wang Y, Sun R, Afolabi A, Mustafina I, Hou J, Zhang S, Yu B. Impact of statins therapy on morphological changes in lipid-rich plaques stratified by 10-Year framingham risk score: A serial optical coherence tomography study. Oncotarget 2017, 5: 27401-27411. PMID: 28404965, PMCID: PMC5432344, DOI: 10.18632/oncotarget.16172.Peer-Reviewed Original ResearchConceptsImpact of statin therapyLipid-rich plaquesStatin therapyFibrous cap thicknessGroup BFramingham risk scoreGroup AOptical coherence tomography studiesRisk scoreBaseline to 6 monthsLower risk group ARisk group ABaseline characteristicsRisk group BMorphological changesTherapyOCT imagesPatientsLipid indicesTomography studiesStatinsPlaqueCHDFraminghamBaselineRole of Optical Coherence Tomography in Diagnosis and Treatment of Patients with Acute Coronary Syndrome
Afolabi A, Hu S, Wang C, Zhu Y, Mustafina I, Lin L, Zheng G, Zhe C, Jia H, Hou J, Yu B. Role of Optical Coherence Tomography in Diagnosis and Treatment of Patients with Acute Coronary Syndrome. Cardiovascular Innovations And Applications 2017, 2: 229-235. DOI: 10.15212/cvia.2016.0054.Peer-Reviewed Original ResearchOptical coherence tomographyTreatment of patientsCoherence tomographyHigh-risk plaquesConstellation of clinical symptomsSpectrum of clinical manifestationsDetecting high-risk plaquesAcute coronary syndromeDetection of high-risk plaquesHigh-resolution imaging modalityAcute myocardial ischemiaClinical manifestationsClinical symptomsCoronary syndromeMyocardial ischemiaImaging modalitiesDisease burdenOcclusive thrombusLuminal thrombosisPathophysiological processesTomographyAtherosclerotic lesionsPatientsHigh-income countriesDiagnosis