2020
Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo
Hiller B, Marmion D, Gross R, Thompson C, Chavez C, Brundin P, Wakeman D, McMahon C, Kordower J. Mitomycin-C treatment during differentiation of induced pluripotent stem cell-derived dopamine neurons reduces proliferation without compromising survival or function in vivo. Stem Cells Translational Medicine 2020, 10: 278-290. PMID: 32997443, PMCID: PMC7848297, DOI: 10.1002/sctm.20-0014.Peer-Reviewed Original ResearchConceptsDopamine neuronsInduced pluripotent stem cellsParkinson's diseaseStem cell-derived dopamine neuronsPD cell therapyMidbrain dopamine neuronsLong-term survivalTransplant of cellsStem cellsHuman induced pluripotent stem cellsPluripotent stem cellsNeuron preparationsMitomycin C treatmentAthymic ratsDrug selectionUndesirable proliferationCell therapyRobust survivalLower proliferationVivo functionNeuronsTransplantationSurvivalProliferative cellsDisease
2009
Culture System for Rodent and Human Oligodendrocyte Specification, Lineage Progression, and Maturation
Espinosa‐Jeffrey A, Wakeman D, Kim S, Snyder E, de Vellis J. Culture System for Rodent and Human Oligodendrocyte Specification, Lineage Progression, and Maturation. Current Protocols In Stem Cell Biology 2009, 10: 2d.4.1-2d.4.26. PMID: 19725014, DOI: 10.1002/9780470151808.sc02d04s10.Peer-Reviewed Original Research