Sorting of secretory proteins at the trans-Golgi network by human TGN46
Lujan P, Garcia-Cabau C, Wakana Y, Lillo J, Rodilla-Ramírez C, Sugiura H, Malhotra V, Salvatella X, Garcia-Parajo M, Campelo F. Sorting of secretory proteins at the trans-Golgi network by human TGN46. ELife 2024, 12: rp91708. PMID: 38466628, PMCID: PMC10928510, DOI: 10.7554/elife.91708.Peer-Reviewed Original ResearchConceptsSecretory proteinsSorting of secretory proteinsCargo-sorting functionsTrans-Golgi networkNascent carriersCargo sortingLumenal domainMutagenesis approachTGN46Quantitative fluorescence microscopyCellular functionsMolecular playersTGNTransport carriersProteinFluorescence microscopyMembrane carrierSorting functionFundamental processesSortingCargoMutagenesisExportPAUFReceptors