Distraction Enterogenesis in Rats: A Novel Approach for the Treatment of Short Bowel Syndrome
O’Quin C, Clayton S, Trosclair L, Meyer H, Dao N, Minagar A, White L, Welch V, Solitro G, Alexander J, Sorrells D. Distraction Enterogenesis in Rats: A Novel Approach for the Treatment of Short Bowel Syndrome. Pathophysiology 2024, 31: 388-397. PMID: 39189165, PMCID: PMC11348226, DOI: 10.3390/pathophysiology31030029.Peer-Reviewed Original ResearchTreatment of short bowel syndromeIn vivo rat studyRat intestinal modelShort bowel syndromeSprague Dawley ratsSmall intestineParenteral nutritionBowel histologyBowel lengthDawley ratsLength-tension relationshipMucosal erosionsRat small intestineRat studiesBowel syndromeEx vivoRatsBowel tissueFailure loadPost-deploymentPatientsBowelHistologyLoad test dataIntestinal modelHistologic Analysis of ‘Distraction Vaginogenesis’ in a Rat Model
Meyer H, Trosclair L, Clayton S, O’Quin C, Crochet C, Colvin J, Welch V, Alhaque A, Solitro G, Shah-Bruce M, Alexander J, Sorrells D. Histologic Analysis of ‘Distraction Vaginogenesis’ in a Rat Model. Pathophysiology 2024, 31: 298-308. PMID: 38921727, PMCID: PMC11206798, DOI: 10.3390/pathophysiology31020022.Peer-Reviewed Original ResearchVaginal agenesisStained with hematoxylin and eosin (H&ERat vaginal tissueSprague Dawley ratsLocal immune reactionHematoxylin and eosin (H&EParaffin-embedded tissuesMasson's trichrome stainingAnti-desmin antibodiesMullerian agenesisResin capEosin (H&EVaginal tissueSurgical vaginoplastyVaginal canalDesmin immunostainingCanal lengthSubmucosal eosinophiliaMechanical dilatationNeutrophilic inflammationPost-surgicalDawley ratsChronic inflammationRat modelTrichrome staining