Grants and contracts awarded to Yale School of Medicine

Federal

• Serap Aksoy, NIH, Trypanosome Gene Expression in Tsetse, 2 years, $163,500
• Robert Alpern, NIH, Regulation of Renal Bicarbonate and Chloride Absorption, 5 years, $2,043,750
• Roland Baron, NIH, Role of the c-SRS Proto-Oncogene in Osteoblasts, 5 years, $1,798,500
• Sumita Bhaduri-McIntosh, NIH, Early Cellular Immune Responses to EBV, 4 years, $535,680
• Angelique Bordey, NIH, GABA Signaling in the Postnatal Subventricular Zone, 4 years, $1,483,007
• Robert Camp, NIH, Qualitative Analysis of Tissue Biomarkers and Pathways, 2 years, $281,220
• Michael Caplan, NIH, Ion Pump Partners: Regulators of Sorting and Function, 4 years, $1,702,179
• Sonia Caprio, NIH, Pathophysiology of Type 2 Diabetes in Youth, 5 years, $2,043,750
• R. Todd Constable, NIH, Epileptogenic Tissue Localization Using EEG-fMRI, 4 years, $1,500,511
• Joseph Craft, NIH, Immune Responses in Lupus, 5 years, $1,635,000
• Ralph DiLeone, NIH, Role of the Orexin Neuropeptide in Responses to Morphine, 5 years, $1,455,000
• Daniel DiMaio, NIH, Cell Transformation by Bovine Papillomavirus, 5 years, $2,630,896
• Ronald Duman, NIH, Antidepressants and Signal Transduction and Gene Expression, 5 years, $1,818,750
• Jack Elias, NIH, Protease/Cathepsin-Mediated Apoptosis in COPD, 4 years, $1,635,000
• Jorge Galan, NIH, Molecular Genetic Analysis of Salmonella Cell Invasion, 1 year, $2,343,717
• Joel Gelernter, NIH, Genetics of Opioid Dependence, 5 years, $5,779,192
• Sankar Ghosh, NIH, Subversion of Innate Immune Responses by Brucella, 2 years, $433,750
• Thomas Gill, NIH, Epidemiology of Disability and Recovery in Older Persons, 5 years, $3,152,866
• Daniel Goldstein, NIH, Strategies to Enhance Immunity in Aging, 3 years, $648,000
• Carlos Grilo, NIH, Patient-Oriented Research with a Focus on Eating and Weight Disorders, 5 years, $597,160
• Steven Hebert, NIH, Structure and Function of ROMK Channel in Kidney, 4 years, $1,370,692
• Zeev Kain, NIH, Parent/Health Care Provider Behaviors & Child’s Anxiety, 5 years, $2,659,446
• Harlan Krumholz, NIH, Telemonitoring to Improve Heart Failure Outcomes, 4 years, $6,664,663
• Nian Liu, NIH, Content-Based Indexing and Retrieval of Brain Odor Maps, 3 years, $470,339
• Angeliki Louvi, NIH, Development of Choroid Plexus and the Blood-CSF Barrier, 2 years, $395,933
• Shrikant Mane, NIH, Yale Microarray Center for Research on the Nervous System, 5 years, $6,509,106
• Linda Mayes, NIH, Cortical Maturation and ERPS in Cocaine-Exposed Children, 5 years, $631,800
• Diane McMahon-Pratt, NIH, Intervenable Host Leishmania (Viannia) Interactions, 5 years, $5,166,089
• Thomas Morgan, NIH, Genetic Risk Factors for Myocardial Infarction, 5 years, $846,072
• A. David Paltiel, NIH, Evaluating the Link Between HIV Prevention and Treatment, 3 years, $1,487,112
• Jordan Pober, NIH, Human CTL-Mediated Injury of Graft Endothelial Cells, 5 years, $2,177,410
• Marc Potenza, NIH, fMRI of Craving in Addictions: Gender Differences, 5 years, $1,604,920
• Kenneth Pugh, NIH, Neurobiological Foundations in Reading (Dis)Ability, 5 years, $2,970,826
• Timothy Quan, NIH, The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus, 5 years, $613,967
• Gary Rudnick, NIH, Structure and Function of NSS Transporters, 4 years, $1,238,981
• Charles Sanislow, NIH, Cognitive Control in Borderline & Trauma Psychopathology, 5 years, $887,895
• William Sessa, NIH, Regulation of Vascular Remodeling & Angiogenesis by Nogo, 5 years, $2,043,750
• Nenad Sestan, NIH, Molecular Control of Cortical Neural Stem Cells, 5 years, $1,717,912; NIH, Neurobiology of Speech and Language Development, 4 years, $1,512,376
• Albert Shaw, NIH, Top3 Homologues in Lymphocyte Genome Stability and Aging, 5 years, $1,417,925
• Dieter Söll, NSF, Expanding the Genetic Code with Phosphoserine and Pyrrolysine, 1 year, $171,569
• Stephen Strittmatter, NIH, Axonal Growth Cone Signal Transduction, 4 years, $1,512,376
• Zhaoxia Sun, NIH, SCO, a Zebrafish Model, Links Cilia and Kidney Cysts, 5 years, $1,921,125
• Patrick Sung, NIH, DNA Repair Genes & Proteins of the RAD52 Group, 5 years, $1,941,565
• Edwin Thrower, NIH, Pancreatic Zymogen Activation in a Reconstituted System, 2 years, $260,800
• Helen Treloar, NIH, Development of the Primary Olfactory Pathway, 5 years, $1,430,625
• Marietta Vazquez, NIH, Epidemiology of Human Metapneumovirus Infection, 5 years, $676,986
• Marney White, NIH, Craving, Binge Eating, and Obesity, 5 years, $671,571
• John Wysolmerski, NIH, Function of the Calcium-Sensing Receptor in the Breast, 5 years, $1,675,875

Non-Federal

• Patrick Allen, National Alliance for Research on Schizophrenia and Depression, Analysis of Protein Phosphatase-Mediated Glutamate Receptor Regulation, 2 years, $60,000
• George Anderson, University of Pittsburgh, Neurobiology, Impulsivity and Alcoholism, 4 years, $45,404
• Titus Boggon, American Society of Hematology, Structure/Function Studies of Janus Kinase Family Members, 1 year, $50,000
• Alfred Bothwell, Robert Leet and Clara Guthrie Patterson Trust, Bioengineering Functional Islets for Treatment of Type 1 Diabetes, 1 year, $59,999
• H. Kim Bottomly, Mount Sinai School of Medicine, Immunobiology of Peanut Allergy and Its Treatment: A Prototype, 5 years, $239,654
• Demetrios Braddock, American Cancer Society, Inc., Molecular Determinants of Nucleic Acid Recognition by KH Domains, 2 years, $720,000
• Christopher Breuer, American Surgical Association, Investigating the Growth Potential of Tissue-Engineered Venous Conduits in a Juvenile Lamb Model, 2 years, $75,000
• Darlene Brunzell, National Alliance for Research on Schizophrenia and Depression, Beta2 Nicotinic Acetylcholine Receptors Affect Schizophrenia Phenotypes via Modulation of CREB, 2 years, $59,968
• João Cabral, American Heart Association (Heritage Affiliate), Biophysical Studies of a Bacterial Cyclic Nucleotide-Regulated Channel, 3 years, $198,000
• Cecilia Canessa, American Heart Association (Heritage Affiliate), Functional Analysis of SGK1 in Vivo, 3 years, $198,000
• Daniel Chase, National Parkinson Foundation, Inc., Identification of the Molecular Mechanisms of Dopamine Signaling, 1 year, $40,000
• Yung-Chi Cheng, Kagoshima University, Novel Nucleoside Reverse Transcriptase Inhibitors Active Against Multi-Drug Resistance HIC-1, 1 year, $35,736
• Hongbo Chi, Arthritis National Research Foundation, SIPI-Mediated Regulation of Autoimmune Disease, 1 year, $50,000
• Chuhan Chung, American Liver Foundation, Hepatocellular Carcinoma and Hepatic Stellate Cells Express Antiangiogenic Pigment Epithelium-Derived Factor; Epigenetic Regulation of PEDF Occurs Through DDR2 Activation on HSC, 3 years, $225,000
• David Cone, National Academies of Emergency Dispatch, Can EMD Conserve ScarceEMSResources?, 1 year, $3,500
• Vladimir Coric, National Alliance for Research on Schizophrenia and Depression, Endocannabinoid Receptor Modulation and Obsessive-Compulsive Disorder: A Double Blind, Placebo-Controlled Pilot Study of Dronabinol Addition in Serotonin-Reuptake Inhibitor-Resistant OCD, 2 years, $59,760
• Kristina Crothers, American Lung Association, Chronic Obstructive Pulmonary Disease in HIV-Positive Compared to HIV-Negative Patients, 1 year, $40,000
• Madison Cuffy, The Thoracic Surgery Foundation for Research and Education, The Role of Indoleamine 2,3-Diosygenase (IDO) on Modulation of Immune Responses in Inflammatory Arterial Diseases, 2 years, $50,000
• Jan Czyzyk, American Cancer Society, Inc., Alternative Effectors of Ras GTPase in T Cell Activation, 4 years, $720,000
• Pietro De Camilli, G. Harold and Leila Y. Mathers Charitable Foundation, Molecular Mechanisms of Synaptic Vesicle Biogenesis, 3 years, $1,650,179
• Marie Egan, Cystic Fibrosis Foundation, Cystic Fibrosis Center, 1 year, $55,310
• Barbara Ehrlich, American Society of Nephrology, Regulation and Function of Polycystin-2, 1 year, $50,000
• Richard Flavell, Bill and Melinda Gates Foundation, A Mouse Model to Evaluate Live Attenuated Vaccine Candidates, 5 years, $16,968,506; Alzheimer’s Association, An Inducible Mouse to Elucidate the Role of Immunity/Inflammation in AD, 3 years, $234,498
• Gerald Friedland, Virginia Commonwealth University, Opioids and HIV Medications: Interactions in Drug Users, 1 year, $37,632
• Mark Gerstein, Rutgers University, Structural Genomics of Eukaryotic Domain Families, 5 years, $230,041
• Daniel Goldstein, American Society of Transplantation, Role of the Innate Immune Ligand Heat Shock Protein 70 in Transplantation, 2 years, $80,000
• Jonathan Grauer, Medtronic, Inc., New Zealand White Rabbit Pseudarthrosis Study Evaluating INFUSE and CRM Products, 1 year, $210,138
• Handan Gunduz-Bruce, National Alliance for Research on Schizophrenia and Depression, GABA-Glutamate Interactions and Psychosis, 2 years, $30,000
• Ann Haberman, The S.L.E. Foundation, Inc., How Germinal Centers Select High-Affinity B Cells: Determination of Cellular Interactions and Migratory Behavior via Intravital Microscopy, 3 years, $150,000
• Ala Haddadin, Union Mutual Foundation, High-Dose Statin Therapy in the Preoperative Period, 2 years, $25,000
• Bryan Hains, Pfizer, Inc., Pifzer Scholars in Pain Medicine, 2 years, $123,000
• Martha Harding, AGA Foundation for Digestive Health and Nutrition, Hepatitis C Virus Infection of Human Liver-Chimeric Mice, 3 years, $195,000
• Lise Heginbotham, American Heart Association (Heritage Affiliate), Regulation of Ca2+ Transport Proteins, 3 years, $198,000
• Josephine Hoh, The Ellison Medical Foundation, Trans-Racial Gene Mapping for Age-Related Macular Degeneration, 4 years, $200,000
• Akiko Iwasaki, Burroughs Wellcome Fund, Stromal Cell Contributions in Innate and Adaptive Immune Response to Mucosal Viral Infection, 5 years, $400,000
• Jeffrey Kahn, American Heart Association (Heritage Affiliate), The Role of a Novel Human Coronavirus in Kawasaki Disease, 3 years, $198,000
• Insoo Kang, American Foundation for AIDS Research, The Effect of Aging on IL-7 Mediated CD8+ T Cell Survival, 2 years, $60,000
• Anil Karihaloo, National Kidney Foundation, VEGF Signaling in Renal Tubular Epithelia, 1 year, $100,000
• Stuart Katz, American Heart Association, Erythropoietin in Acute Myocardial Infarction, 1 year, $66,000
• Barbara Kazmierczak, L2 Diagnostics, LLC, Virulence Typing of Pseudomonas Clinical Isolates, 1 year, $158,204
• Judith Kidd, University of Florida, Taste Psychophysics, 1 year, $76,779
• Fadi Lakkis, American Society of Nephrology, Model Organism to Study Innate Allorecognition, 1 year, $50,000
• Angelika Lampert, Epilepsy Foundation of America, Control of Excitability in Rodent Spike-Wave Seizures by Voltage-Gated Sodium Channels, 1 year, $40,000
• Brian Leaderer, Brigham and Women’s Hospital, Gene by Environment Interactions in Asthma and Allergy, 1 year, $185,331
• Patty Lee, American Lung Association, MIMED Mechanisms of VEGF and HO-1, 1 year, $60,000
• Xin Li, Arthritis Foundation, Role of Borrellia burgdoferi NapA in Lyme Arthritis, 2 years, $150,000
• Yi-Hwa Liu, American Heart Association (Heritage Affiliate), Development of Quantitative High Resolution and High Sensitivity for Targeted Molecular Imaging, 3 years, $198,000
• Elias Lolis, The Campbell Foundation, CXCR4 Allosteric Agonists, 1 year, $11,603
• Gero Miesenböck, The Dana Foundation, Illuminating the Function of Hypothalamic Feeding Circuits, 3 years, $300,000
• Angus Nairn, Rockefeller University, Molecular Actions of Neuroleptic Drugs, 1 year, $288,288
• Michael Nitabach, Whitehall Foundation, Inc., Clock-Membrane Coupling in Circadian Pacemaker Neurons, 1 year, $75,000
• Aldo Peixoto, Satellite Research, Hemodynamic and Hormonal Response to Dialysate Sodium Individualization in Hemodialysis Patients, 1 year, $50,000
• Patricia Preisig, University of Texas Southwestern Medical Center at Dallas, The Formulation of a Rational Therapy of Nephrolithiasis, 3 years, $123,703
• Timothy Quan, Arthritis Foundation, The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus, 2 years, $150,000; Abbott Laboratories, Inc., The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus, 1 year, $72,000
• Gary Rudnick, National Alliance for Autism Research, Mutation Associated with Asperger’s Syndrome—Effect on Amine Transporter System, 2 years, $120,275
• Raymond Russell, Dr. Robert C. Atkins Foundation, Effects of a High-Protein Ketogenic Diet on Myocardial Metabolism, 1 year, $91,615
• Kristi Sacco, National Alliance for Research on Schizophrenia and Depression, Effects of Atomoxetine on Cognitive Function in Schizophrenia, 2 years, $60,000
• Mary Schwab-Stone, Fundación Quiera, Quiera-Yale Children of the Street, 1 year, $10,211
• Gerald Shadel, A-T Childrens’ Project, Aberrant Regulation of Mitochondrial DNA in Ataxia-Telangiectasia, 2 years, $42,263
• Arthur Simen, National Alliance for Research on Schizophrenia and Depression, Quantitative Trait Mapping in a Large Mormon Pedigree with Severe Depression and Anxiety, 2 years, $60,000
• Albert Sinusas, GE Healthcare Ltd., Evaluation of Ventricular Remodeling in Animals Using SPECT Imaging After Myocardial Infarction, 7 months, amount confidential
• William Sledge, Eli Lilly and Company, YNHH Recidivist Program Prevention Evaluation with Six Sigma Methodology, 1 year, $129,553
• Stefan Somlo, The Joseph LeRoy and Ann C. Warner Fund, Inc., ARPKD Research, 1 year, $25,000
• Julie Sosa, Patrick and Catherine Weldon Donaghue Medical Research Foundation, Neurocognitive Changes in Primary Hyperparathyroidism, 3 years, $179,374
• Julie Staley-Gottschalk, National Alliance for Research on Schizophrenia and Depression, Antidepressant-Mediated Adaptations in Nicotinic Acetylcholine Receptor Expression, 2 years, $60,000
• Mary Tomayko, Dermatology Foundation, Phenotypic and Functional Analysis of Memory B cells, 3 years, $165,000
• Flora Vaccarino, National Alliance for Autism Research, Molecular Mechanisms of Cerebral Cortical Overgrowth, 2 years, $119,276
• Lisa Walke, American Geriatrics Society, Barriers to and Facilitators of Effective Symptom Management in Older Adults with Chronic Obstructive Pulmonary Disease, 2 years, $130,000
• Li Wen, American Diabetes Association, Inc., The Role of Toll in Autoimmune Diabetes, 3 years, $300,000
• Kevin White, University of California–Riverside, Molecular Bases of Ecdysteroid Action in the Mosquito, 5 years, $157,982
• Catherine Yeckel, American Diabetes Association, Inc., Mild Cold Exposure: A Non-Pharmacological Approach to Improve Insulin Sensitivity In Obese Youth, 3 years, $414,000
• Mark Yeckel, National Parkinson Foundation, Inc., Dopaminergic and Cholinergic Control of Inhibitory Connectivity Between Direct and Indirect Output Pathways of the Neostriatum Background, 1 year, $40,000
• Jiasheng Zhang, American Society of Nuclear Cardiology, Imaging of Matrix Metalloproteinase Activity in Thoracic Aortic Aneurysm: A Pilot Study, 1 year, $25,000

CORRECTION: The listing in Volume 1, Issue 3 for Brian Leaderer’s 5-year NIH grant, Indoor and Outdoor NO2 and Asthma Severity in Children, was incorrect. The correct grant amount is $6,544,369, for 5 years.