Rani Hoff, MPH, PhD
Cards
Appointments
Additional Titles
Director, Northeast Program Evaluation Center
Director, Evaluation Division, National Center for PTSD
Contact Info
Appointments
Additional Titles
Director, Northeast Program Evaluation Center
Director, Evaluation Division, National Center for PTSD
Contact Info
Appointments
Additional Titles
Director, Northeast Program Evaluation Center
Director, Evaluation Division, National Center for PTSD
Contact Info
About
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Titles
Emeritus Professor of Psychiatry
Director, Northeast Program Evaluation Center; Director, Evaluation Division, National Center for PTSD
Biography
Rani Hoff received both her MPH in chronic disease epidemiology and her PhD in mental health services research and psychiatric epidemiology from Yale University School of Public Health. Dr. Hoff served until 2025 as Director of the Northeast Program Evaluation Center (NEPEC), responsible for national program evaluation of mental health services in the Department of Veterans Affairs nationally. NEPEC is located within the Office of Mental Health and Suicide Prevention in the Department of Veterans Affairs and also oversees several national clinical and quality improvement initiatives in VA, including the Psychotropic Drug Safety Initiative and the Measurement Based Care Initiative. She was also the Director of the Evaluation Division of the National Center for PTSD. At the national level, Dr. Hoff advised senior leadership within the VA Office of Mental Health and Suicide Prevention and other areas of VA Central Office regarding VA performance with respect to mental health services and programming. As Director of NEPEC she directly or indirectly oversaw program evaluation for acute inpatient and residential treatment programs, vocational services for Veterans with serious mental illness, intensive community mental health care and day programs, specialized PTSD services, team-based care in outpatient settings, community-based interventions for suicide prevention, tele-mental health services for suicide prevention and services provided to women Veterans. As part of evaluation, she was responsible for overseeing the collection and analyses of data, construction of performance monitoring and performance measures, data-based decision making tools for leadership at all levels of VA and partnering with QI experts to identify and improve mental health services at all VA facilities. She has also served on several advisory committees to the VA on the mental health needs of female veterans, with particular attention to military sexual trauma. She also co-chaired the Behavioral Health Council for the VA transition to the Oracle electronic medical record, a group that ensures that the medical record is built and functions well for VA mental health providers and programs.
Some of her recent work has focused on diversity, equity and inclusion. As a member of the OMHSP DEI Steering Committee (DEISC) she contributed to the extensive efforts of the Office in the DEI space. She also co-chaired the Data and Disparities sub-committee of the DEISC, which focuses on the development of guidance, tools and data identifying disparities in access to, and utilization of, mental health services; consultation for local facilities charged with identifying disparities and addressing them; and providing support for programs needing to meet the January 2023 Joint Commission guidelines on social determinants of health and health disparities.
Dr. Hoff’s research utilizes principles of psychiatric epidemiology, services research, quality improvement, program evaluation research, and implementation science to examine risk factors and correlates of psychiatric disorders and suicide behaviors, with particular attention paid to co-occurring disorders and vulnerable populations; mental health service provision in both VA and non-VA settings, including the contribution of community and background environmental factors in the quality of care and clinical outcomes; and the epidemiology of behavioral addictions. This research has included studies on pathological gambling, schizophrenia, substance abuse/dependence, the risk of suicide in psychiatric patients, trauma and comorbidity, criminal justice mental health, and the mental health problems experienced by the homeless and by returning Veterans from the Middle East. She was Principal Investigator of the Survey of the Experiences of Returning Veterans (SERV) a large VA-funded study of the gender differences in coping behaviors of Veterans returning from military service; the Veterans Outcomes Assessment, an annual nationally representative sample of 15,000 VA mental health patients with clinical outcomes measures after the first three months of treatment; and the Veteran Satisfaction Survey, an annual sample of 20,000 of those receiving VA mental health services that assesses access to care and perceived quality of services.
As an emeritus Professor, Dr. Hoff is focusing on supporting the Department in its ongoing efforts to connect to, and support, the New Haven community; supporting and mentoring students, fellows and junior faculty; doing historical research on the history of mental health treatment in the US; and working with the public to de-stigmatize mental health care and encourage young people to enter mental health careers.
Appointments
Psychiatry
EmeritusPrimary
Other Departments & Organizations
Education & Training
- PhD
- Yale University (1994)
- MPH
- Yale University (1991)
- BS
- Mercyhurst University, Mathematics and Biology (1985)
Research
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Overview
- Health correlates of compulsive video game playing, shopping, and stealing among high school students in CT
- Associations between gambling behaviors and other health and risk behaviors in adolescents
- Gender differences in the association between deployment experiences and substance use and abuse in veterans returning from Iraq and Afghanistan (SERV Study)
- Use of CAM services in the treatment of PTSD
- Pain as a mediator of the association between childhood abuse and onset of major depression in adults
- Predictors of the use of residential treatment services in VA
- Differential mortality in Veterans with and without mental illness
- Surgical outcomes in Veterans with and without mental illness
- Cardiac outcomes in Veterans with and without mental illness
- Gender differences in the correlates of cutting behavior in adolescents
Medical Research Interests
ORCID
0000-0002-7023-3171
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Sandra Resnick, PhD
Carolyn M. Mazure, PhD
Robert Rosenheck, MD
Georgina Gross, PhD
Ilan Harpaz-Rotem, PhD, ABPP
Marc Potenza, PhD, MD
Veterans
Substance-Related Disorders
Disruptive, Impulse Control, and Conduct Disorders
Women
Ill-Housed Persons
Publications
2025
Unraveling PTSD: Symptom Cluster Change During and 1 Year After Veterans’ Residential PTSD Treatment
Gross G, Spiller T, Ben-Zion Z, Rubenstein A, Pietrzak R, Duek O, Hoff R, Harpaz-Rotem I. Unraveling PTSD: Symptom Cluster Change During and 1 Year After Veterans’ Residential PTSD Treatment. Psychological Trauma Theory Research Practice And Policy 2025, 17: 1780-1788. PMID: 38990694, DOI: 10.1037/tra0001734.Peer-Reviewed Original ResearchCitationsAltmetricConceptsPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersPosttraumatic stress disorder clustersSymptom clustersIntrusive symptomsResidential treatmentTreatment of posttraumatic stress disorderPosttraumatic stress disorder symptomsResidential PTSD treatmentPTSD symptom clustersNovel treatment interventionsDifferential treatment responseReduce symptom severityDifferential patterns of changeAvoidance symptomsPTSD treatmentTreatment gainsStress disorderVeterans AffairsSymptom severityCluster CTreatment interventionsCluster BIndividual symptomsCohort of veteransClinical Outcomes of Telehealth‐Based Cognitive Behavioral Therapy for Suicide Prevention in the US Department of Veterans Affairs
Betthauser L, Walker J, van Engelen L, Lhermitte S, Ilgen M, Hoff R, Stacy M. Clinical Outcomes of Telehealth‐Based Cognitive Behavioral Therapy for Suicide Prevention in the US Department of Veterans Affairs. Suicide And Life-Threatening Behavior 2025, 55: e70044. PMID: 41059601, DOI: 10.1111/sltb.70044.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsVeterans Health AdministrationSuicide preventionSuicidal self-directed violenceCognitive behavioral therapyCBT-SPVA health care systemUS Department of Veterans AffairsDepartment of Veterans AffairsSuicide-related copingElectronic health recordsHealth care systemEvidence-based practiceInitial outcomesBehavioral therapyUS DepartmentVHA careTelehealth programHealth recordsVeterans AffairsSelf-directed violenceCare systemHealth AdministrationTelehealth platformUS veteransSelf-EfficacyA Multilevel Investigation of Potential Inequities in the Volume of Mental Health Care Received by Black Veterans Health Administration Patients
Boden M, Katz I, Harris A, Hoff R, Trafton J. A Multilevel Investigation of Potential Inequities in the Volume of Mental Health Care Received by Black Veterans Health Administration Patients. Psychological Services 2025, 22: 584-595. PMID: 40244979, DOI: 10.1037/ser0000936.Peer-Reviewed Original ResearchAltmetricConceptsVeterans Health AdministrationMental health careHealth careNon-black patientsBlack patientsPotential inequalitiesVeterans Health Administration patientsIncrease health equityMental health patientsCross-sectional retrospective observational studyMental health conditionsMental health treatmentNegative binomial regressionHealth equityStaffing ratiosHealth patientsFacility-level analysisVHA patientsHealth treatmentHealth AdministrationHigher overall volumeHealth conditionsBinomial regressionLess careCare
2024
Associations of Posttraumatic Stress Disorder Symptom Clusters and Pain Interference in Post-9/11 Veterans: Exploring Sleep Impairment and Physical Activity as Underlying Mechanisms
Emrich M, Gnall K, Garnsey C, George J, Park C, Mazure C, Hoff R. Associations of Posttraumatic Stress Disorder Symptom Clusters and Pain Interference in Post-9/11 Veterans: Exploring Sleep Impairment and Physical Activity as Underlying Mechanisms. International Journal Of Behavioral Medicine 2024, 32: 371-384. PMID: 38438749, DOI: 10.1007/s12529-024-10268-4.Peer-Reviewed Original ResearchAltmetricConceptsPost-9/11 veteransPain interferencePhysical activityPTSD symptomsAssociated with pain interferenceModifiable health factorsSleep impairmentSymptom clustersPosttraumatic stress disorder symptom clustersWorsening pain interferencePTSD symptom clustersRe-experiencing symptomsBackgroundPosttraumatic stress disorderHealth factorsSecondary analysisTargeting sleepMethodsThe present studyVeteransHyperarousal symptomsRe-experiencingStress disorderStudy variablesPTSDPainAssociated with changesPhysical activity, posttraumatic stress, and gender: A longitudinal study of post-9/11 veterans
Gnall K, Sacco S, Sinnott S, Park C, Mazure C, Hoff R. Physical activity, posttraumatic stress, and gender: A longitudinal study of post-9/11 veterans. Journal Of Health Psychology 2024, 29: 1576-1589. PMID: 38400566, DOI: 10.1177/13591053241233380.Peer-Reviewed Original ResearchCitationsConceptsPost-9/11 veteransLeisure-time PAPhysical activityPosttraumatic stress symptomsPA engagementMilitary dischargeSelf-report questionnairesHealth habitsMental healthSecondary analysisStudy baselineLongitudinal relationshipPosttraumatic stressStress symptomsVeteransLongitudinal studyHealthObservational investigationPost-9/11GenderBaselineEngagementQuestionnaireInterventionParticipants
2023
Additional comparisons between PHQ-9 responses from clinical and survey data
Katz I, Resnick S, Liebmann E, Hoff R. Additional comparisons between PHQ-9 responses from clinical and survey data. Psychiatry Research 2023, 326: 115286. PMID: 37302356, DOI: 10.1016/j.psychres.2023.115286.Peer-Reviewed Original ResearchMeaning in life as a mechanism between perceived posttraumatic growth and subsequent mental health in OEF/OIF/OND military veterans
David A, Park C, Sacco S, Kraus S, Hoff R. Meaning in life as a mechanism between perceived posttraumatic growth and subsequent mental health in OEF/OIF/OND military veterans. The Journal Of Positive Psychology 2023, 19: 490-498. DOI: 10.1080/17439760.2023.2218342.Peer-Reviewed Original ResearchCitationsOutcomes for treatment of depression in the Veterans Health Administration: Rates of response and remission calculated from clinical and survey data
Liebmann E, Resnick S, Hoff R, Katz I. Outcomes for treatment of depression in the Veterans Health Administration: Rates of response and remission calculated from clinical and survey data. Psychiatry Research 2023, 324: 115196. PMID: 37058792, DOI: 10.1016/j.psychres.2023.115196.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsElectronic health recordsVeteran patient populationPatient populationRate of responseEHR dataInformation Set (HEDIS) quality measuresHealthcare Effectiveness DataPatient-reported outcomesPatient Health QuestionnaireTreatment of depressionVeterans Health AdministrationRoutine clinical assessmentPHQ-9 dataGroup of veteransClinical characteristicsVeteran patientsPatient outcomesClinical assessmentDepression responseHealth QuestionnaireHealth AdministrationEffectiveness dataOverall populationRemissionHealth recordsComparative effectiveness of evidence-based psychotherapies for PTSD delivered in VA residential PTSD treatment
Sippel L, Gross G, Spiller T, Duek O, Smith N, Hoff R, Harpaz-Rotem I. Comparative effectiveness of evidence-based psychotherapies for PTSD delivered in VA residential PTSD treatment. Psychological Medicine 2023, 53: 6859-6866. PMID: 36971021, DOI: 10.1017/s0033291723000375.Peer-Reviewed Original ResearchCitationsAltmetricConceptsResidential Rehabilitation Treatment ProgramPosttraumatic stress disorderCognitive processing therapyComparative effectivenessProlonged exposureFirst-line treatmentSevere posttraumatic stress disorderRehabilitation treatment programSelf-reported posttraumatic stress disorderDepressive symptom outcomesDepressive symptom severityEvidence-based psychotherapiesElectronic medical recordsResidential PTSD treatmentSymptomatic patientsComorbid conditionsMedical recordsPE groupSymptom outcomesIndividual cognitive processing therapyDepressive symptomsPTSD treatmentSymptom severityTreatment programProgram evaluation dataUnderstanding veteran barriers to specialty outpatient PTSD clinical care
Rozek D, Steigerwald V, Baker S, Gross G, Maieritsch K, Hoff R, Harpaz-Rotem I, Smith N. Understanding veteran barriers to specialty outpatient PTSD clinical care. Journal Of Anxiety Disorders 2023, 95: 102675. PMID: 36854224, DOI: 10.1016/j.janxdis.2023.102675.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSpecialty outpatient clinicsPosttraumatic stress disorderOutpatient clinicPTSD specialty clinicClinical characteristicsMale sexPTSD symptom severitySpecialty clinicWhite raceClinical careClinical concernTreatment engagementSymptom severityStress disorderClinicGreater likelihoodVeteransSignificant minorityTreatmentImpact of demographicsMulti-faceted barriersCareFiscal year 2019DemographicsNational sample
Academic Achievements & Community Involvement
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Honors
honor Section Chair, Mental Health Section
11/07/2009National AwardAmerican Public Health AssociationDetailsUnited Stateshonor Section Chair, Mental Health Section
11/07/2006National AwardAmerican Public Health AssociationDetailsUnited States
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Psychiatry
1518 Crest Rd
Wynnewood, PA 19096
United States
Locations
Department of Psychiatry
Academic Office
1 Church Street
New Haven, CT 06510