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Yale Psychiatry Grand Rounds: Karasu Psychosocial Lecture: "Well-Being and Human Flourishing: Perspectives from Contemplative Neuroscience"

December 20, 2024

December 20, 2024

Karasu Psychosocial Lecture: "Well-Being and Human Flourishing: Perspectives from Contemplative Neuroscience"

Richard Davidson, PhD, William James and Vilas Professor of Psychology and Psychiatry, University of Wisconsin-Madison

ID
12591

Transcript

  • 00:00Much, John
  • 00:02John and Matt.
  • 00:04Appreciate it and,
  • 00:07really happy to be with
  • 00:08you all today.
  • 00:10I'm gonna share my slides.
  • 00:13Let me do that now.
  • 00:21Can you all see that?
  • 00:23Yes.
  • 00:24Okay.
  • 00:26So it really is
  • 00:30an honor to share with
  • 00:31you a little bit about
  • 00:32our journey today.
  • 00:34Let me begin by
  • 00:37situating the work we're doing
  • 00:38in a broader
  • 00:40historical context of work that
  • 00:41I've been doing
  • 00:42over the course of my
  • 00:43entire career.
  • 00:45I began my career
  • 00:47asking a very simple question.
  • 00:50That question is still pertinent
  • 00:52to much of what we
  • 00:53do today.
  • 00:54And the question is, why
  • 00:56is it that some people
  • 00:59are more vulnerable
  • 01:00to life's slings and arrows,
  • 01:02and why are others more
  • 01:03resilient?
  • 01:05In the early part of
  • 01:06my career, I focused a
  • 01:07lot on the adversity
  • 01:09side of this
  • 01:11equation and studied brain mechanisms
  • 01:13that conferred
  • 01:15vulnerability
  • 01:16to depression and anxiety and
  • 01:18stress related disorders.
  • 01:20And,
  • 01:21my life
  • 01:22changed considerably.
  • 01:25It went through what one
  • 01:26of my dear friends calls
  • 01:27an orthogonal rotation,
  • 01:30when I,
  • 01:32met the Dalai Lama for
  • 01:33the first time in nineteen
  • 01:34ninety two.
  • 01:37And it was at this
  • 01:38meeting when,
  • 01:40he asked me very innocently,
  • 01:42why can't we use the
  • 01:44same tools
  • 01:45of behavioral and neural,
  • 01:48neuroscience that we're using to
  • 01:50interrogate anxiety and stress
  • 01:52and use those tools to,
  • 01:55study the positive qualities of
  • 01:57what it means to be
  • 01:58human,
  • 02:00qualities like kindness
  • 02:01and like compassion.
  • 02:03And, I did not have
  • 02:04a very good answer for
  • 02:05him on that day,
  • 02:07but I did make a
  • 02:08commitment to him that I
  • 02:10was going to
  • 02:11orient our work toward,
  • 02:14these
  • 02:15the study of these qualities,
  • 02:17and that led to the
  • 02:18founding of the Center for
  • 02:19Healthy Minds
  • 02:21in,
  • 02:24in two thousand ten, and
  • 02:26the Dalai Lama came out
  • 02:27to inaugurate that center in
  • 02:28two thousand ten. And the
  • 02:30mission of our center is
  • 02:32to cultivate well-being
  • 02:33and relieve suffering through the
  • 02:35scientific
  • 02:36understanding of the mind.
  • 02:38And in twenty fourteen, as,
  • 02:40Matt kindly mentioned,
  • 02:42we founded the nonprofit Healthy
  • 02:44Minds Innovations to translate
  • 02:47insights that were coming from
  • 02:49the science
  • 02:50into tools that can be
  • 02:51used to,
  • 02:53both measure and disseminate well-being
  • 02:55at scale.
  • 02:57So let me begin with
  • 02:58a disclaimer. I'm the founder,
  • 03:00president, and chief visionary of
  • 03:01Healthy Minds Innovations,
  • 03:03which is a nonprofit
  • 03:04organization from which I've never
  • 03:06received a penny in compensation.
  • 03:11This is a,
  • 03:15an inspirational
  • 03:16photograph. This came from,
  • 03:19one of the many visits
  • 03:20that Dalai Lama made to
  • 03:22our center
  • 03:23in Madison.
  • 03:25We were this was actually
  • 03:26taken in,
  • 03:28two thousand one.
  • 03:31Some of you,
  • 03:32might recognize from the little
  • 03:34snippet of profile,
  • 03:36on the other side of
  • 03:37the Dalai Lama, this side
  • 03:39away from me.
  • 03:40That's Ned Kellen. Some of
  • 03:42you may recognize him as
  • 03:43the he's the chair of
  • 03:45our psychiatry department. He's been
  • 03:47also the he's the editor
  • 03:48of the American Journal.
  • 03:52We were showing him how
  • 03:53we can interrogate the structure
  • 03:55and function of the brain.
  • 03:57This was in the early
  • 03:58days of MRI two thousand
  • 04:00one,
  • 04:01and, this was a very
  • 04:03important demonstration for the Dalai
  • 04:05Lama because he saw how
  • 04:07mental activity actually,
  • 04:09was associated with systematic changes
  • 04:13in the functional activity of
  • 04:14the brain,
  • 04:15and,
  • 04:16that was an important
  • 04:19demonstration
  • 04:20for him to be able
  • 04:21to witness.
  • 04:23Okay. So I wanna begin
  • 04:25this presentation
  • 04:26with a little bit of
  • 04:27bad news. I promise I
  • 04:29won't linger
  • 04:30on the bad news for
  • 04:31too long, but I it's
  • 04:33news that all of you
  • 04:35know,
  • 04:36but I just wanna review
  • 04:37a few key data points,
  • 04:40that really underscore the importance,
  • 04:42I think, of the approach
  • 04:44that we are taking,
  • 04:46that well-being is indeed in
  • 04:48rapid decline.
  • 04:50Some of you might be
  • 04:51aware that each year over
  • 04:52the last, ten years,
  • 04:55there is an a thing
  • 04:56called the world happiness report
  • 04:58that has been issued in
  • 04:59part under the auspices of
  • 05:01the United Nations.
  • 05:02And,
  • 05:03one of the
  • 05:06forms of data in this
  • 05:08annual report is not simply
  • 05:11a cross sectional snapshot of,
  • 05:15indicators of happiness across nations
  • 05:17in the world, but it's
  • 05:19also looking at the longitudinal
  • 05:21trend,
  • 05:22in that is changes in
  • 05:25these metrics of happiness or
  • 05:27well-being
  • 05:28over time,
  • 05:29in different nations throughout the
  • 05:32world.
  • 05:32And, I'd like to share
  • 05:34with you data. This is
  • 05:35looking at changes
  • 05:37over the course of a,
  • 05:39ten year period,
  • 05:41from
  • 05:43around,
  • 05:45twenty eleven to thirteen to
  • 05:48twenty,
  • 05:49twenty
  • 05:51two to twenty three.
  • 05:53And this is,
  • 05:56listed,
  • 05:57in this table in order,
  • 06:00in the order of countries,
  • 06:04starting with the countries that
  • 06:05showed the largest increase in
  • 06:08happiness or well-being
  • 06:10over the course of this
  • 06:12period.
  • 06:13And,
  • 06:14the data in the world
  • 06:15happiness report,
  • 06:17is for,
  • 06:19I think,
  • 06:21a hundred and thirty or
  • 06:22a hundred and thirty one
  • 06:23countries,
  • 06:24across the world. So,
  • 06:26I'm now showing you,
  • 06:28just a list of countries.
  • 06:30This first page goes from
  • 06:32one to thirty
  • 06:33thirty six. This goes from
  • 06:35thirty seven to sixty six,
  • 06:39and then this goes down
  • 06:41to
  • 06:42ninety seven. And then I
  • 06:44wanna show you where the
  • 06:45United States falls.
  • 06:47United States falls,
  • 06:49one hundred and twenty out
  • 06:50of one hundred and thirty
  • 06:51or one hundred and thirty
  • 06:53one countries
  • 06:54in showing the,
  • 06:55largest
  • 06:56declines
  • 06:58in,
  • 07:00happiness or well-being
  • 07:02over the course of this,
  • 07:05decade.
  • 07:07We are
  • 07:08the two countries that are
  • 07:10just above us are Panama
  • 07:12and Colombia with,
  • 07:16Pakistan just above that.
  • 07:19And so,
  • 07:21this is just one of
  • 07:23many indications
  • 07:24that particularly in our country,
  • 07:26well-being is in rapid decline.
  • 07:28Many of you, I'm sure,
  • 07:29are aware of,
  • 07:31the surgeon general's
  • 07:33reports related to mental health.
  • 07:36This was from twenty twenty
  • 07:39three. It's the first time
  • 07:40United States surgeon general
  • 07:42ever issued a health advisory
  • 07:44on loneliness and social isolation.
  • 07:47And, I wanna just show
  • 07:49you a few data points
  • 07:50from that report.
  • 07:53In the upper left hand
  • 07:54figure,
  • 07:55is a measure of the
  • 07:59change
  • 08:00in social isolation
  • 08:02over the course of a
  • 08:05roughly,
  • 08:06seventeen year period from two
  • 08:08thousand three to two thousand
  • 08:10twenty.
  • 08:12And, what is indicated here
  • 08:14is an increase
  • 08:16of twenty four hours per
  • 08:18month
  • 08:19in the amount of social
  • 08:20isolation
  • 08:22that, the average citizen in
  • 08:24the US
  • 08:25is,
  • 08:26experiencing.
  • 08:27If you look at the
  • 08:28panel in the lower left
  • 08:29hand corner,
  • 08:31that's a metric of social
  • 08:32engagement with friends,
  • 08:35and it's showing a decline
  • 08:36of twenty hours per month
  • 08:39in the amount of time
  • 08:40we spend with friends.
  • 08:43And these represent
  • 08:45changes that are quite significant
  • 08:48in the ecology of our
  • 08:50social lives,
  • 08:52and,
  • 08:53really,
  • 08:55underscore
  • 08:56the,
  • 08:57the the tremendous,
  • 08:59change that has occurred
  • 09:01that was not due to
  • 09:03COVID.
  • 09:04It may have been exacerbated
  • 09:06by COVID in particular cases,
  • 09:08but, these trends clearly,
  • 09:12were present prior to COVID.
  • 09:16Now something,
  • 09:17that really is quite astounding
  • 09:19that was in the surgeon
  • 09:20general's report is that,
  • 09:23social isolation is a greater
  • 09:25risk factor for premature mortality
  • 09:28than is smoking fifteen cigarettes
  • 09:30a day.
  • 09:32These kind of findings,
  • 09:34underscore the fact that these,
  • 09:37social,
  • 09:38changes,
  • 09:39changes in the social fabric
  • 09:41of our lives
  • 09:43get under the skin
  • 09:44and affect our biology
  • 09:46in ways that are consequential
  • 09:48for health.
  • 09:49These data show that
  • 09:51social isolation
  • 09:53is greater than twofold a
  • 09:55risk factor compared to obesity
  • 09:58in,
  • 09:59its association
  • 10:00with premature mortality.
  • 10:02So,
  • 10:04remarkably,
  • 10:05just a couple of weeks
  • 10:06after the surgeon general issued
  • 10:08this report, he issued another
  • 10:09report on social media and
  • 10:11youth mental health.
  • 10:13And, I won't, go through
  • 10:16extensively
  • 10:17the data in this report,
  • 10:18but I wanna call your
  • 10:19attention to one specific,
  • 10:22set of findings.
  • 10:24This, was in the surgeon
  • 10:26general's report.
  • 10:28And if you look on
  • 10:29the right hand side of
  • 10:31this figure,
  • 10:33these are data for comorbid
  • 10:36problems
  • 10:37combining internalizing and externalizing
  • 10:39problems in use.
  • 10:41And it's looking at the
  • 10:44prevalence of these problems,
  • 10:46scaled by the amount of
  • 10:48social media per day
  • 10:50that youth are using.
  • 10:52And what you can see
  • 10:53is that youth who are
  • 10:55spending,
  • 10:56six hours or more a
  • 10:58day on social media have
  • 11:00greater than twenty twenty percent
  • 11:02risk
  • 11:03for,
  • 11:06these comorbid
  • 11:07internalizing and externalizing
  • 11:09problems.
  • 11:10And, there's you can see
  • 11:12this linear scaling
  • 11:14with the amount
  • 11:15of social media consumption.
  • 11:17In the US today, teenagers
  • 11:19spend an average of three
  • 11:20and a half hours a
  • 11:21day on social media. And
  • 11:23this is not just total
  • 11:24screen time. This is just
  • 11:26the amount of screen time
  • 11:28that is allocated
  • 11:29to social media.
  • 11:31So,
  • 11:33we really have a crisis,
  • 11:35and,
  • 11:38I think that the standard
  • 11:40solutions that we've been applying
  • 11:43have been less than,
  • 11:45successful.
  • 11:47I wanna just show you
  • 11:48one other data point, and
  • 11:49then I'll stop the bad
  • 11:50news.
  • 11:51And this is simply a
  • 11:53large scale,
  • 11:55global study looking at the
  • 11:57relation
  • 11:58between,
  • 11:59the average well-being in a
  • 12:01country and life expectancy.
  • 12:04And this is looking at
  • 12:05a hundred and fifty one
  • 12:06countries throughout the world.
  • 12:08And what you can see
  • 12:09is that there's a very,
  • 12:11strong association when you look
  • 12:13at it this way between
  • 12:14the average well-being of the
  • 12:16country
  • 12:17and life expectancy.
  • 12:18And if you look at
  • 12:19the countries in the upper
  • 12:21right hand quadrant of this
  • 12:23scatter plot
  • 12:24and compare them to the
  • 12:25countries that are depicted in
  • 12:27the lower left
  • 12:29quadrant of the scatter plot,
  • 12:31these are massive differences in
  • 12:33life expectancy. These differences in
  • 12:35life expectancy exceed twenty years.
  • 12:38And so these are not
  • 12:39small statistical differences. These are
  • 12:42massive differences
  • 12:43that really matter,
  • 12:45and,
  • 12:47the association with well-being is
  • 12:49quite striking.
  • 12:52So many of you in
  • 12:53this audience, I'm sure, recognize,
  • 12:56this person. This is Tom
  • 12:57Insel. He was the former
  • 12:59director of NIMH,
  • 13:01someone
  • 13:02that I'm sure many of
  • 13:03you know well.
  • 13:05He's a friend of mine
  • 13:06too.
  • 13:07And I wanna read to
  • 13:08you,
  • 13:10an excerpt from an interview
  • 13:11that
  • 13:12was,
  • 13:16was made with with Tom
  • 13:19a few years ago. This
  • 13:21is,
  • 13:21several years after he retired,
  • 13:23and,
  • 13:25it's quite,
  • 13:27I think, provocative
  • 13:28what he said in this
  • 13:29interview.
  • 13:31He said he spent thirteen
  • 13:32years at NIMH
  • 13:34really pushing
  • 13:35on the neuroscience and genetics
  • 13:37of mental disorders.
  • 13:38And when I look back
  • 13:40on this, I realized that
  • 13:41while I think I succeeded
  • 13:43at getting lots of really
  • 13:45cool papers published by cool
  • 13:47scientists
  • 13:48at fairly large costs. I
  • 13:50think twenty billion dollars. I
  • 13:52don't think we move the
  • 13:53needle in reducing suicide,
  • 13:57reducing hospitalizations,
  • 13:59improving recovery
  • 14:01for the tens of millions
  • 14:02of people who have mental
  • 14:03illness, I hold myself accountable
  • 14:05for that.
  • 14:06Quite a statement from,
  • 14:09from Tom.
  • 14:11And,
  • 14:12I served on the board
  • 14:13of scientific counselors at NIMH,
  • 14:16during the time Tom was,
  • 14:20director.
  • 14:21And,
  • 14:22I can tell you, and
  • 14:23I'm sure many of you
  • 14:24know, that he wasn't a
  • 14:25big fan of psychosocial
  • 14:28interventions
  • 14:29at that time.
  • 14:30And,
  • 14:34a number of years later,
  • 14:36twenty fourteen to be exact,
  • 14:38he and I appeared on
  • 14:40a, in a dialogue together
  • 14:43in Davos, Switzerland at the
  • 14:44World Economic Forum talking about
  • 14:46the,
  • 14:47benefits of mindfulness,
  • 14:49as a
  • 14:51strategy in working with people
  • 14:53who have various kinds of
  • 14:57mental health symptoms.
  • 15:00And so,
  • 15:02he really,
  • 15:03has shifted quite a bit,
  • 15:05and,
  • 15:07I,
  • 15:08use that as a
  • 15:10a framework to introduce
  • 15:12the main topic.
  • 15:14And the main topic of
  • 15:16this talk really can be
  • 15:17summarized in this simple claim,
  • 15:21that
  • 15:22is really the conclusion
  • 15:24of fifteen years of research
  • 15:26in our center and also,
  • 15:30supported by findings from many
  • 15:32other scientists.
  • 15:34And that is that well-being
  • 15:35is best regarded as a
  • 15:36skill
  • 15:37that can be learned.
  • 15:39I think that,
  • 15:41while simple, this is quite
  • 15:42a radical
  • 15:44conclusion as well.
  • 15:46And,
  • 15:47we believe that the evidence
  • 15:49really supports this.
  • 15:51And if you really believe
  • 15:53the data,
  • 15:56you will see why we,
  • 15:58and we also encourage others,
  • 16:01to become activist scientists,
  • 16:04in a way that is
  • 16:05not too dissimilar
  • 16:06from the way climate scientists,
  • 16:09are,
  • 16:11acting in the world.
  • 16:14I feel like we if
  • 16:15this
  • 16:17claim is really true, we
  • 16:19have a moral obligation,
  • 16:22to bring these practices out
  • 16:24into the world in a
  • 16:25responsible way,
  • 16:28given that the world is
  • 16:30really falling apart in so
  • 16:32many ways.
  • 16:33And, a lot of the,
  • 16:37problems many of the problems
  • 16:38that we see in the
  • 16:39world today
  • 16:40stem from fundamentally,
  • 16:43failures to flourish,
  • 16:45and a,
  • 16:46a lack of,
  • 16:48cultivating
  • 16:50the innate capacities that I
  • 16:51think every human being,
  • 16:54is,
  • 16:55endowed with. And so,
  • 16:57the rest of this talk
  • 16:58will really be focused on
  • 17:00these issues.
  • 17:03So,
  • 17:04one of the insights
  • 17:06that we've
  • 17:07gleaned from our work is
  • 17:09that the same mechanisms
  • 17:11that,
  • 17:14encode suffering,
  • 17:17such as neuroplasticity
  • 17:18and epigenetics
  • 17:20can be harnessed for the
  • 17:21good, and these are mechanisms
  • 17:24that turn out to be
  • 17:25engaged
  • 17:26when we train our minds,
  • 17:29for well-being.
  • 17:32So
  • 17:32I want to now focus
  • 17:34on the
  • 17:35constituents
  • 17:36of resilience and flourishing, what
  • 17:38contributes to them. And here,
  • 17:41I'd like to
  • 17:42introduce you to a framework
  • 17:44that we published a few
  • 17:45years ago in this paper
  • 17:47called the plasticity
  • 17:49of well-being,
  • 17:51a training based framework for
  • 17:52the cultivation of human flourishing.
  • 17:55And, in this
  • 17:57paper, we
  • 17:59harnessed,
  • 18:02the data from both neuroscience
  • 18:05as well as,
  • 18:07from the contemplative
  • 18:08traditions
  • 18:09and
  • 18:10asked where there are commonalities,
  • 18:14across these very different
  • 18:17but overlapping
  • 18:18Venn diagrams, if you will,
  • 18:21and,
  • 18:22what are the key constituents
  • 18:24that we can identify
  • 18:26as necessary
  • 18:28and sufficient
  • 18:29for the cultivation of human
  • 18:31flourishing.
  • 18:32And we,
  • 18:34came up with four key
  • 18:36pillars,
  • 18:37and I'd like to introduce
  • 18:39you to these pillars.
  • 18:40The first pillar we call
  • 18:42awareness.
  • 18:46And awareness
  • 18:48is,
  • 18:49excuse me, is fundamentally
  • 18:50about
  • 18:52being present.
  • 18:54It is where mindfulness would
  • 18:56be. It includes self awareness.
  • 18:59It also includes
  • 19:01what psychologists and neuroscientists
  • 19:04have called meta awareness,
  • 19:06which is,
  • 19:07the capacity to know what
  • 19:09our minds are doing,
  • 19:13which may sound strange to
  • 19:14some people.
  • 19:16But I'm sure,
  • 19:18that many of you I
  • 19:19certainly have had this experience.
  • 19:21Many of you had the
  • 19:21experience
  • 19:22of reading a book where
  • 19:24you might be reading each
  • 19:25word on a page, and
  • 19:26you might be reading one
  • 19:29page, a second page, and
  • 19:30after a few minutes,
  • 19:32you recognize
  • 19:33that you have no idea
  • 19:34what you've just read.
  • 19:36Your mind is elsewhere.
  • 19:39The moment we recognize that
  • 19:41is a moment of meta
  • 19:42awareness,
  • 19:43and that is something
  • 19:45that indeed can be trained.
  • 19:49The second pillar we call
  • 19:51connection. Connection is about
  • 19:53feeling connected to others. It
  • 19:55includes qualities that are important
  • 19:57for healthy
  • 19:58social relationships,
  • 20:00qualities such as appreciation,
  • 20:02kindness, compassion.
  • 20:04This is really,
  • 20:05the
  • 20:07antithesis
  • 20:08of loneliness,
  • 20:10and,
  • 20:11we there's a wealth of
  • 20:13evidence
  • 20:14to suggest
  • 20:15that,
  • 20:16this is, a critical element
  • 20:19of well-being.
  • 20:21The third pillar we call
  • 20:23insight. Insight is about a
  • 20:25curiosity
  • 20:26driven
  • 20:27self
  • 20:28knowledge, and,
  • 20:29it's a knowledge specifically
  • 20:31about the narrative
  • 20:33of ourselves
  • 20:34that every human
  • 20:36has.
  • 20:37We all carry around this
  • 20:39narrative, and we know that
  • 20:41there are some people who
  • 20:42have a negative narrative, who
  • 20:44have negative beliefs about themselves,
  • 20:47low expectations of themselves.
  • 20:49And, of course, we know
  • 20:50that that is associated
  • 20:52with,
  • 20:54depression and other forms of
  • 20:56psychopathology.
  • 20:58And what we have learned,
  • 21:01from a lot of work
  • 21:03is that
  • 21:04what's really important for well-being,
  • 21:06particularly initially,
  • 21:08is not so much changing
  • 21:09the narrative, but it's changing
  • 21:11our relationship to this narrative
  • 21:13so that we can see
  • 21:14the narrative for what it
  • 21:16is,
  • 21:16essentially a constellation of thoughts,
  • 21:20and beliefs.
  • 21:21And, again, this is something
  • 21:22that can be trained,
  • 21:24and we know that when
  • 21:26it is trained,
  • 21:28there is an improvement in
  • 21:29their well-being.
  • 21:31And finally, the last pillar
  • 21:33we call purpose. Purpose is
  • 21:34about staying motivated.
  • 21:36It's about clarifying our
  • 21:38true north in life, clarifying
  • 21:40our values.
  • 21:41And it's not so much
  • 21:43about finding something, quote, more
  • 21:44purposeful to do, but how
  • 21:46can we find meaning and
  • 21:48purpose
  • 21:49in even the most pedestrian
  • 21:51activities of daily living?
  • 21:53In taking out the garbage,
  • 21:55be connected to your sense
  • 21:57of purpose.
  • 21:58And, of course, it could
  • 21:59be.
  • 22:00It simply requires a little
  • 22:02bit of reframing.
  • 22:03And,
  • 22:05this is an area which
  • 22:06is particularly
  • 22:07interesting and illuminating because,
  • 22:10even the,
  • 22:12chores, the so called chores
  • 22:14that we do on a
  • 22:15regular basis can be real
  • 22:17opportunities
  • 22:19for growth and for,
  • 22:23flourishing,
  • 22:24with this really simple
  • 22:26kind of reframing
  • 22:28that is quite easy to
  • 22:30do.
  • 22:31Okay.
  • 22:32So I'm now gonna,
  • 22:34take a deeper dive and,
  • 22:38introduce you to some key
  • 22:40findings in each of these
  • 22:42areas.
  • 22:43The first,
  • 22:44pillar
  • 22:45awareness,
  • 22:46of course,
  • 22:48has been around for a
  • 22:49long time.
  • 22:51One of my heroes,
  • 22:53is William James,
  • 22:55who you see here. And,
  • 22:58William James
  • 22:59had a two volume tome,
  • 23:02published in eighteen ninety called
  • 23:04the principles of psychology.
  • 23:06He has a whole chapter
  • 23:07in there on attention.
  • 23:09And,
  • 23:10I wanna read to you,
  • 23:13one of the passages from
  • 23:15this chapter, which is really,
  • 23:17one of my all time
  • 23:18favorite quotes in the,
  • 23:21in in the study of
  • 23:22the mind.
  • 23:24And, William James said the
  • 23:26faculty of voluntarily
  • 23:28bringing back
  • 23:29a wandering intention
  • 23:30over and over again is
  • 23:32the very root of judgment,
  • 23:34character, and will.
  • 23:35No one is
  • 23:37if you have it not.
  • 23:39An education which should improve
  • 23:41this faculty
  • 23:42would be the education
  • 23:43par excellence,
  • 23:45but it is easier to
  • 23:46define this ideal
  • 23:48than to give practical directions
  • 23:49for bringing it about.
  • 23:51The italics, by the way,
  • 23:53are in the original William
  • 23:54James.
  • 23:56This is really quite an
  • 23:57extraordinary passage and, I think,
  • 23:59very visionary,
  • 24:01and underscores the value that
  • 24:03he attached to
  • 24:05the possibility
  • 24:07of educating attention.
  • 24:08And we know,
  • 24:11I should put it this
  • 24:12way. If there is one
  • 24:13thing we know from the
  • 24:14empirical study
  • 24:16of meditation
  • 24:17and related practices over the
  • 24:19last
  • 24:20fifteen years, it is that
  • 24:23attention can be educated.
  • 24:26And,
  • 24:27if we really believe this,
  • 24:29this is one area where
  • 24:31I think we especially
  • 24:32have a moral obligation
  • 24:35to
  • 24:35introduce this in a widespread
  • 24:37way into our society,
  • 24:40particularly for children.
  • 24:42We know that if kids
  • 24:43are not attending to
  • 24:45information
  • 24:46that is presented,
  • 24:49their capacity to learn that
  • 24:51material will be significantly compromised.
  • 24:54And so this is a
  • 24:56huge
  • 24:56opportunity
  • 24:58that I think, has,
  • 25:00we now know about,
  • 25:02and, we are insufficiently
  • 25:04harnessing.
  • 25:06Let me just give you,
  • 25:08you know, one little,
  • 25:10or two little data points
  • 25:12about
  • 25:13the study of these qualities.
  • 25:16And one of the ways
  • 25:17we began to do this,
  • 25:19soon after the Dalai Lama
  • 25:20was encouraging us to,
  • 25:22study practices in his tradition
  • 25:26that might be
  • 25:31transformed
  • 25:32to be more secular.
  • 25:33And, he
  • 25:35specifically told us that to
  • 25:37do that and if we
  • 25:38find that they're valuable,
  • 25:40to disseminate them widely.
  • 25:42And so this is just
  • 25:44a picture of a
  • 25:46Tibetan monk in our lab,
  • 25:48and someone who actually is
  • 25:50quite well known. He is
  • 25:52a young Tibetan monk by
  • 25:54the name of Meeg Gyor
  • 25:55Rinpoche,
  • 25:56and
  • 25:58he generously,
  • 26:00spent many, many hours in
  • 26:01our lab,
  • 26:03over,
  • 26:04the last fifteen years.
  • 26:06And this is,
  • 26:08during an early session with
  • 26:10him in
  • 26:11two thousand two,
  • 26:13where we were recording brain
  • 26:15electrical activity from him,
  • 26:17while he was meditating and
  • 26:19during different,
  • 26:21states, or tasks of attention.
  • 26:24And,
  • 26:25one of the
  • 26:27things that we observed, and
  • 26:28this came from a paper
  • 26:30that was published in two
  • 26:31thousand four.
  • 26:33This was the very first
  • 26:34paper on meditation ever published
  • 26:36in PNAS.
  • 26:38And,
  • 26:40what these data show is
  • 26:42an elevation
  • 26:43in gamma oscillations,
  • 26:45that we record from the
  • 26:47scalp surface.
  • 26:51And,
  • 26:52these gamma oscillations
  • 26:54are especially pronounced
  • 26:56during meditation
  • 26:58when,
  • 26:59attention is
  • 27:01specifically enhanced.
  • 27:04And you can see with
  • 27:05the naked eye
  • 27:06the
  • 27:07enhancement of gamma oscillations.
  • 27:09There's also increased synchrony of
  • 27:11these oscillations
  • 27:13over widespread regions of the
  • 27:15cortex.
  • 27:17And,
  • 27:19in addition, in this first
  • 27:20paper, we showed that these
  • 27:22gamma oscillations
  • 27:24were significantly,
  • 27:26more prevalent in the brains
  • 27:29of these long term meditators
  • 27:31than in the brains of
  • 27:33age and gender match controls,
  • 27:37revealing
  • 27:38a possible
  • 27:39trait difference,
  • 27:41between
  • 27:42the long term meditators and
  • 27:44the controls.
  • 27:46And this was really our
  • 27:47first indication
  • 27:49that there was a there
  • 27:50there, that there was something
  • 27:51different
  • 27:52about the brains of these
  • 27:53long term meditators.
  • 27:55And I should say that
  • 27:57this group of long term
  • 27:58meditators
  • 27:59was a group of really
  • 28:01long term meditators.
  • 28:04Number of hours of lifetime
  • 28:06practice in this group that
  • 28:08was published in this paper
  • 28:09in two thousand four was
  • 28:11thirty four thousand hours.
  • 28:14You can do the arithmetic
  • 28:15at home, but thirty four
  • 28:16thousand hours is a big
  • 28:18number.
  • 28:19These are,
  • 28:21people who've spent,
  • 28:23the better part of their,
  • 28:25adult lifetime
  • 28:27meditating.
  • 28:29So
  • 28:31this was very interesting, but,
  • 28:33you know, I don't have
  • 28:34to tell this audience that
  • 28:36while these kinds of findings
  • 28:37are intriguing,
  • 28:39they're far from definitive.
  • 28:41They,
  • 28:42there there's so many differences
  • 28:44between
  • 28:45a person who elects to
  • 28:47spend their life in this
  • 28:48way
  • 28:49compared to,
  • 28:50age and gender match controls.
  • 28:53These these
  • 28:56groups differ in so many
  • 28:57different ways, and a skeptic
  • 29:00might claim that these differences
  • 29:02might have been there in
  • 29:03the first place.
  • 29:04They might be associated with
  • 29:06factors that predispose a person
  • 29:08to choose a life of
  • 29:09this kind,
  • 29:11and they may not have
  • 29:12anything to do with meditation.
  • 29:13Although we,
  • 29:15did find that there were
  • 29:16associations
  • 29:17between
  • 29:18the magnitude of gamma oscillations
  • 29:20that we saw
  • 29:21and the number of lifetime
  • 29:23hours of practice,
  • 29:25but even that is simply
  • 29:27a correlation.
  • 29:28And so we needed to
  • 29:29do other kinds of designs,
  • 29:32and that's exemplified in work
  • 29:35we did related to the
  • 29:36connection,
  • 29:38pillar.
  • 29:40So I wanna
  • 29:41share with you,
  • 29:43a, an important early study
  • 29:46that we did looking at
  • 29:47in a randomized controlled trial,
  • 29:50looking at people who never
  • 29:51meditated,
  • 29:52and teaching them,
  • 29:54a very simple practice to
  • 29:56cultivate compassion.
  • 29:58And,
  • 29:59we taught them that practice
  • 30:01for two weeks, only two
  • 30:03weeks,
  • 30:04and we looked at changes
  • 30:05in their brain over this
  • 30:07very short period of time.
  • 30:09So let me just say
  • 30:10a little bit about what
  • 30:12we taught them.
  • 30:14In this particular study, we
  • 30:15recruited participants
  • 30:17who were told that they
  • 30:19were going to be randomly
  • 30:20assigned
  • 30:21to one of two conditions,
  • 30:23both of which,
  • 30:25we have reason to believe
  • 30:27should improve their well-being.
  • 30:29In one condition, we taught
  • 30:30them a simple practice to
  • 30:32cultivate compassion.
  • 30:34And in this practice, participants
  • 30:36were invited
  • 30:38to bring
  • 30:39a person into their mind,
  • 30:42and we begin with a
  • 30:43loved one,
  • 30:45bring a person who is
  • 30:47close to you. It could
  • 30:48be a family member,
  • 30:50a very close friend.
  • 30:52Bring that person into your
  • 30:54mind and your heart.
  • 30:56And
  • 30:57think of a time in
  • 30:57their life when they may
  • 30:58have been having some challenge
  • 31:00or difficulty,
  • 31:01and then cultivate the genuine
  • 31:03aspiration
  • 31:04that they'd be relieved of
  • 31:05that suffering.
  • 31:07And we taught them simple
  • 31:09phrases to use that they
  • 31:10repeat silently in their mind
  • 31:12to remind them of this.
  • 31:14May you be happy.
  • 31:17May you be free of
  • 31:18suffering and the causes of
  • 31:20suffering,
  • 31:21phrases of that kind.
  • 31:23And they were
  • 31:24encouraged to choose their own
  • 31:26phrase if they wish, whatever
  • 31:28words
  • 31:29felt
  • 31:30appropriate to them that conveyed
  • 31:32a similar meaning.
  • 31:33And they began with a
  • 31:34loved one. They and then
  • 31:35moved on to themselves.
  • 31:38They then moved on to
  • 31:39a category that we call
  • 31:41a stranger, a person whose
  • 31:43face you recognize, but you
  • 31:44don't know them well, could
  • 31:46be someone who works in
  • 31:47the same office that you
  • 31:48work in the same building,
  • 31:50but you don't know much
  • 31:51about their lives.
  • 31:52And imagine a time in
  • 31:53their life when they may
  • 31:54have been having some difficulty
  • 31:56even if you don't know
  • 31:57much about their life, and
  • 31:58then go through the same
  • 32:00kind of process.
  • 32:02And finally, we end with
  • 32:04a
  • 32:04difficult person, someone who pushes
  • 32:06your buttons.
  • 32:10And we encourage
  • 32:11the participant
  • 32:13to genuinely
  • 32:14bring that person into their
  • 32:16life,
  • 32:18in a
  • 32:20sincere way and cultivate the
  • 32:22aspiration that they'd be relieved
  • 32:24of suffering.
  • 32:25So they do that for
  • 32:27thirty minutes a day for
  • 32:28two weeks.
  • 32:29We have a control group
  • 32:31that's taught simple practices
  • 32:33derived from cognitive therapy.
  • 32:37They are taught to cognitively
  • 32:39reappraise
  • 32:39situations
  • 32:40to render them,
  • 32:43more positive in outcome,
  • 32:46and they are taught for
  • 32:48the same amount of time.
  • 32:50And these,
  • 32:51this training is delivered online
  • 32:53to these people,
  • 32:54and we scan them before
  • 32:56and after they go through
  • 32:57this training. We also, at
  • 32:59the end of the training,
  • 33:00give them a
  • 33:03a task
  • 33:04from
  • 33:05behavioral and neuroeconomics,
  • 33:08a task that is designed
  • 33:10to assess altruism,
  • 33:12costly altruism.
  • 33:13And, these are data from
  • 33:15the
  • 33:16economic decision making task,
  • 33:19simply showing that the participants
  • 33:21randomly assigned to compassion training
  • 33:24behave significantly more altruistically
  • 33:26compared to their counterparts
  • 33:28assigned to the cognitive reappraisal
  • 33:30training. And we also find
  • 33:32that there are differences in
  • 33:33the brain,
  • 33:35and these differences in the
  • 33:36brain actually predict,
  • 33:38the change in behavior on
  • 33:40the economic decision making task.
  • 33:43And here, we're specifically showing
  • 33:45changes in connectivity
  • 33:46between a region in dorsolateral
  • 33:49prefrontal cortex
  • 33:50and in the ventral striatum,
  • 33:52particularly in the nucleus accumbens
  • 33:54here.
  • 33:55And increases in connectivity
  • 33:57between these regions
  • 33:59predict the increase that we
  • 34:01see in altruistic
  • 34:02behavior
  • 34:03on the economic decision making
  • 34:05task
  • 34:06in the participants
  • 34:07who are trained in compassion.
  • 34:10So,
  • 34:11this is simply a proof
  • 34:12of concept that,
  • 34:14it really doesn't take much.
  • 34:16This is after two weeks
  • 34:17of training.
  • 34:18It's a maximum of seven
  • 34:20hours,
  • 34:21thirty minutes a day for
  • 34:22two weeks.
  • 34:23And,
  • 34:24it's simply just to illustrate
  • 34:27that,
  • 34:28you can actually see changes
  • 34:30in the brain with as
  • 34:31little as seven hours of
  • 34:33training.
  • 34:34I'm not in any way
  • 34:35meaning to imply
  • 34:37that these changes are gonna
  • 34:38persist.
  • 34:40If you did two weeks
  • 34:42of physical exercise with a
  • 34:43trainer
  • 34:44and noticed improvements in how
  • 34:46your body is feeling, nobody
  • 34:48would expect those changes to
  • 34:50persist if you stopped exercising.
  • 34:53Our conjecture
  • 34:54is that in all of
  • 34:55this, we're,
  • 34:57teaching people these simple practices,
  • 34:59which hopefully can become lifelong
  • 35:02practices,
  • 35:03that then will,
  • 35:05enable
  • 35:05these changes to endure.
  • 35:10Actually, I'm gonna skip this
  • 35:11in the interest of time
  • 35:13and,
  • 35:13move on to insight.
  • 35:17Insight, as I,
  • 35:19mentioned earlier, is insight into
  • 35:22the nature of
  • 35:24the the self,
  • 35:25the entity
  • 35:27that,
  • 35:28we all carry around,
  • 35:30our narrative
  • 35:31self.
  • 35:32And,
  • 35:33one of the interesting ways
  • 35:36to probe this,
  • 35:37rigorously,
  • 35:38experimentally,
  • 35:40is with challenging,
  • 35:44the self, if you will.
  • 35:46And one of the ways
  • 35:47that we can challenge it
  • 35:49is,
  • 35:50with physical pain.
  • 35:52And I liken this to,
  • 35:55to a cardiac stress test,
  • 35:58to evaluate the functional status
  • 36:00of the heart.
  • 36:02A cardiologist
  • 36:03would often have
  • 36:05a patient,
  • 36:06do a stress test to
  • 36:08look at the functioning of
  • 36:09the heart under these
  • 36:11stressful
  • 36:12challenges.
  • 36:13In a set in a
  • 36:14very similar way, we can
  • 36:15challenge the mind and the
  • 36:17brain with physical pain.
  • 36:20And so,
  • 36:21in these studies, we use
  • 36:23heat,
  • 36:24as a physical pain. It's
  • 36:26very realistic. It's actual heat.
  • 36:28We use a thermode,
  • 36:30that involves
  • 36:31rapidly circulating water,
  • 36:34where,
  • 36:35in which we can control
  • 36:37the temperature very precisely.
  • 36:39And, I wanna share data
  • 36:41with you from,
  • 36:42one experiment,
  • 36:44with long term meditation practitioners
  • 36:46that was a very simple
  • 36:47study.
  • 36:48And in this study, we
  • 36:50gave,
  • 36:51both meditators and controls
  • 36:54a sample of this
  • 36:56heat
  • 36:57stimulus,
  • 36:59before they began the experiment.
  • 37:01The heat is forty nine
  • 37:02degrees centigrade,
  • 37:04delivered for ten seconds.
  • 37:05I've had it done to
  • 37:06myself on many occasions. I
  • 37:08can tell you that it
  • 37:09is indeed extremely painful,
  • 37:13and,
  • 37:14you can,
  • 37:16most people can tolerate it
  • 37:18pretty well for the first
  • 37:19few seconds, but,
  • 37:21getting toward,
  • 37:22seconds,
  • 37:24seven and higher, it's really
  • 37:26very intense.
  • 37:27But we can deliver this
  • 37:29in a way which is
  • 37:30safe, doesn't cause any tissue
  • 37:31damage,
  • 37:33and,
  • 37:34is, very compelling and realistic.
  • 37:38When you think about pain,
  • 37:41we often use a phrase
  • 37:42like, I'm in pain.
  • 37:45And, it's helpful to reflect
  • 37:47on a sentence like that,
  • 37:49because it really helps to
  • 37:51reveal what this insight pillar
  • 37:53is about.
  • 37:54When a person says something
  • 37:56like I am in pain
  • 37:58or even,
  • 37:59you can think of this
  • 38:00kind of phrase with any
  • 38:02emotion, I am sad,
  • 38:04what does it mean to
  • 38:05say that? Does it when
  • 38:07a person says I am
  • 38:08in pain or I am
  • 38:09sad, does that mean all
  • 38:10of you are sad, all
  • 38:12of you are in pain?
  • 38:13Is there any,
  • 38:15is there any place in
  • 38:16you
  • 38:17which is not feeling sad
  • 38:18or not feeling pain? What
  • 38:20is the I actually mean
  • 38:22when we use that kind
  • 38:23of sentence?
  • 38:25And so that's really what
  • 38:27this inside
  • 38:28pillar is about. And there
  • 38:30are specific
  • 38:31meditation practices
  • 38:32that are designed to interrogate
  • 38:35and to undermine,
  • 38:36if you will, this,
  • 38:38constructed
  • 38:39eye.
  • 38:41So,
  • 38:42in this experiment,
  • 38:44and, actually, let me just
  • 38:45say give
  • 38:48another introduction to this experiment
  • 38:50before I share the actual
  • 38:52data.
  • 38:53We have spent a lot
  • 38:55of time in our lab
  • 38:56looking at how people respond
  • 38:58to adversity,
  • 39:00and,
  • 39:01I wanna just show you
  • 39:02two hypothetical curves.
  • 39:04Imagine that at time point
  • 39:06three,
  • 39:07some stressful event is introduced,
  • 39:09and you can see how
  • 39:10this person responds to it.
  • 39:12And on the ordinate, you
  • 39:14can plot your favorite dependent
  • 39:16measure.
  • 39:17It could be a behavioral
  • 39:18measure. It could be something
  • 39:19like cortisol.
  • 39:20It could be a heart
  • 39:22rate. It could even be,
  • 39:24a response in the brain,
  • 39:26which we've looked at such
  • 39:27as bold signal,
  • 39:29to, in the amygdala, for
  • 39:31example.
  • 39:33But contrast this with the
  • 39:35second person
  • 39:36who responds
  • 39:37with the same amplitude,
  • 39:39but they come back down
  • 39:41to baseline more quickly.
  • 39:43We would say that person
  • 39:44b
  • 39:45is more resilient compared to
  • 39:47person a. You can think
  • 39:48of resilience in part as
  • 39:50the rapidity
  • 39:51with which you recover from
  • 39:53adversity.
  • 39:54And so,
  • 39:55this is one of the
  • 39:56parameters
  • 39:57that we're looking at in
  • 39:58this experiment. So in this
  • 40:00experiment, we bring long term
  • 40:02meditators and controls into the
  • 40:04lab. We introduce them to
  • 40:06the heat pain, but we
  • 40:08do it in a way
  • 40:09where we precede it with
  • 40:10a stimulus
  • 40:11that denotes that the pain
  • 40:13is coming on. So,
  • 40:15in this case, an auditory
  • 40:17stimulus,
  • 40:18is presented, and it denotes
  • 40:21that in ten seconds,
  • 40:22they're gonna get zapped with
  • 40:24a,
  • 40:26this noxious
  • 40:27heat.
  • 40:29And we're specifically looking at
  • 40:31the pain matrix in the
  • 40:32brain.
  • 40:33Many of you know that,
  • 40:37the set of regions in
  • 40:38the brain that responds to
  • 40:40physical pain like heat
  • 40:42is fairly well characterized. We
  • 40:44know where to look.
  • 40:46And so in non meditators,
  • 40:48we present,
  • 40:50a simple tone that denotes
  • 40:52that pain is about to
  • 40:53occur. And in the pain
  • 40:55matrix, we see
  • 40:56that non meditators begin to
  • 40:58respond immediately.
  • 41:00This is simply to the
  • 41:01auditory stimulus.
  • 41:03No heat stimulus has been
  • 41:05presented at this time, but
  • 41:07simply in anticipation
  • 41:09of the painful stimulus,
  • 41:11the pain matrix begins to
  • 41:13respond.
  • 41:14When the heat comes on,
  • 41:15the response continues,
  • 41:17and the
  • 41:19recovery is quite slow.
  • 41:22When you bring long term
  • 41:23meditators into the lab, you
  • 41:26show them you introduce the
  • 41:27same parameters.
  • 41:29They hear beep.
  • 41:31And what you see is
  • 41:32absolutely
  • 41:33no significant activation in any
  • 41:36region of the pain matrix.
  • 41:38Absolutely
  • 41:39no,
  • 41:40significant activation.
  • 41:42You do see, of course,
  • 41:44activation in auditory cortex in
  • 41:46response to the tone.
  • 41:48But then when the heat
  • 41:49comes on,
  • 41:51the meditators show a very
  • 41:52large response. And in fact,
  • 41:54in some regions of the
  • 41:55pain
  • 41:56matrix, including
  • 41:57somatosensory
  • 41:58cortex,
  • 41:59they actually show a larger
  • 42:01response,
  • 42:02significantly
  • 42:03larger than in controls,
  • 42:05but they come right back
  • 42:07down to baseline.
  • 42:09And we think of this
  • 42:10as the normal signature of
  • 42:12resilience,
  • 42:13having very little anticipatory response,
  • 42:16a big response to the
  • 42:17actual stimulus,
  • 42:18and a very rapid
  • 42:20return to baseline.
  • 42:23Okay. Let me say a
  • 42:24few things about purpose.
  • 42:28Purpose, as I
  • 42:30suggested earlier, is about finding
  • 42:33our true north,
  • 42:35in life. And there's a
  • 42:37whole cottage industry of
  • 42:39research that indicates that purpose
  • 42:42is,
  • 42:44probably the single most important
  • 42:46psychological
  • 42:47factor
  • 42:48in predicting longevity
  • 42:51among people who are in
  • 42:53their latter decades of life.
  • 42:56And, I wanna just show
  • 42:58you one example from this
  • 42:59kind of study.
  • 43:01This is,
  • 43:02a study
  • 43:03classifying people into the ninetieth
  • 43:06or the tenth percentile in
  • 43:07having
  • 43:08a strong or weak sense
  • 43:10of purpose,
  • 43:11following them over the course
  • 43:13of five years.
  • 43:15These are people in their
  • 43:16seventies,
  • 43:17and it's,
  • 43:18matching people at the out
  • 43:20at the outset of this
  • 43:21study in,
  • 43:22preexisting medical conditions and then
  • 43:25looking at them longitudinally.
  • 43:27And what you can see
  • 43:28is that people who
  • 43:30have the lowest sense of
  • 43:32purpose who are in the
  • 43:33tenth percentile,
  • 43:35on the ordinate is the
  • 43:37hazard ratio for death.
  • 43:39You can see that they're
  • 43:40dying sooner
  • 43:41compared to their counterparts who
  • 43:43are in their the ninetieth
  • 43:44percentile
  • 43:46in the dotted line. And
  • 43:48this basic finding has been
  • 43:50replicated
  • 43:51many, many times,
  • 43:52and,
  • 43:54is quite a strong finding,
  • 43:57underscoring
  • 43:58the importance of purpose in
  • 44:00life,
  • 44:02and its correlates
  • 44:04in suggesting
  • 44:05that it is
  • 44:06something that is,
  • 44:09embodied. It's a quality that
  • 44:11gets under the skin
  • 44:12and affects our biology in
  • 44:14ways that are consequential for
  • 44:16health.
  • 44:18Okay. Now in the last
  • 44:19few minutes, I wanna just
  • 44:21talk a little bit about
  • 44:23scaling well-being.
  • 44:25And this is something,
  • 44:28about which we're
  • 44:30extremely passionate these days.
  • 44:33When people ask me what
  • 44:34I'm really most excited about,
  • 44:36it's really the opportunity
  • 44:38to scale well-being.
  • 44:41Given that I think most
  • 44:43people would agree
  • 44:44as we talked about at
  • 44:46the very beginning of this
  • 44:47presentation,
  • 44:49our well-being is in such
  • 44:51rapid
  • 44:52decline.
  • 44:53And so we
  • 44:55developed a curriculum,
  • 44:57if you will, that we
  • 44:58call the Healthy Minds program
  • 45:00that trains
  • 45:01each of these four pillars
  • 45:03of well-being.
  • 45:04And one of the things
  • 45:05that we've done is we've
  • 45:06put this into a form
  • 45:07of a mobile app,
  • 45:09called the Healthy Minds program.
  • 45:12This app is freely available,
  • 45:14totally free.
  • 45:16There's no paperwork whatsoever. It's
  • 45:18produced by our nonprofit
  • 45:20Healthy Minds Innovations,
  • 45:22and the New York Times
  • 45:23Wirecutter just named it as
  • 45:25one of the three best
  • 45:26meditation apps for the fourth
  • 45:27year in a row.
  • 45:29And in,
  • 45:31my,
  • 45:33admittedly,
  • 45:35biased opinion,
  • 45:37this is the only app
  • 45:38of its kind that actually
  • 45:40is evidence based.
  • 45:42There are two published randomized
  • 45:44controlled trials
  • 45:45using this app and and,
  • 45:47at least two more
  • 45:49about to be published very
  • 45:50soon.
  • 45:52And,
  • 45:53what we see,
  • 45:55and by the way, you
  • 45:56can go to this website,
  • 45:57try healthy minds dot org,
  • 46:00to learn more about it,
  • 46:01and you can download it
  • 46:02from,
  • 46:03the App Store either,
  • 46:06iOS or Google.
  • 46:09These are just data from
  • 46:10two of the randomized controlled
  • 46:12trials that have been published,
  • 46:13one with a sample size
  • 46:15of,
  • 46:16three hundred and forty three,
  • 46:17another with a sample size
  • 46:18of six hundred and sixty
  • 46:20two.
  • 46:21The
  • 46:23the figure on the right
  • 46:25comes from a study of
  • 46:26public school teachers.
  • 46:29And,
  • 46:31it is,
  • 46:33showing a,
  • 46:34quite a dramatic reduction
  • 46:36on standardized measures of distress.
  • 46:39This is a composite measure
  • 46:41that includes measures of depression,
  • 46:43anxiety,
  • 46:44and,
  • 46:46perceived stress.
  • 46:48And what you can see
  • 46:49is that these changes begin
  • 46:51to rapidly
  • 46:52occur,
  • 46:53over the course of four
  • 46:55weeks of training.
  • 46:57So this is a twenty
  • 46:58eight day program,
  • 47:00where people are doing each
  • 47:02pillar
  • 47:03for one week. That is
  • 47:05awareness, connection, insight, and purpose.
  • 47:08And in this app,
  • 47:09they are presented with didactic
  • 47:12information about the science of
  • 47:13each of these pillars in
  • 47:15what you can think of
  • 47:16as many podcasts.
  • 47:18And they're given really simple
  • 47:20short practices
  • 47:21to cultivate,
  • 47:23these qualities,
  • 47:25using a kind of what
  • 47:26we think of as procedural
  • 47:28learning,
  • 47:29skill based and acquired through
  • 47:31practice.
  • 47:32And these data are showing
  • 47:34that these gains
  • 47:35in reductions in psychological distress
  • 47:38are preserved
  • 47:39at three months follow-up. Now
  • 47:41here's the real kicker.
  • 47:43We get from the app
  • 47:44the amount of time people
  • 47:45are spending,
  • 47:47engaging with the app, and
  • 47:49the average use is approximately
  • 47:51five minutes per day.
  • 47:53Five minutes per day for
  • 47:55twenty eight days
  • 47:56is sufficient
  • 47:57to produce robust reductions on
  • 48:00these measures of distress.
  • 48:03So we've
  • 48:05just replicated
  • 48:07this in yet another study
  • 48:09on the right.
  • 48:11This is data from
  • 48:13another school system. This actually
  • 48:15comes from,
  • 48:17the Jefferson County Public School
  • 48:19District in Louisville, Kentucky,
  • 48:22and it's showing,
  • 48:24similar data with a longer
  • 48:28follow-up period.
  • 48:29This is,
  • 48:32at,
  • 48:34twenty eight weeks follow-up,
  • 48:37and it's showing that the
  • 48:38Healthy Minds program,
  • 48:41compared to a more active
  • 48:43control in this case,
  • 48:45rather than a wait list
  • 48:46control is showing,
  • 48:48these benefits.
  • 48:50We also see benefits extending
  • 48:52to the entire school system,
  • 48:54in this case where,
  • 48:56measures of appreciation
  • 48:58and trust in school administrators
  • 49:00is enhanced
  • 49:02in, participants
  • 49:03who are randomly assigned
  • 49:05to the,
  • 49:07control group. And I don't
  • 49:08have a slide of this,
  • 49:09but we just finished,
  • 49:12analyzing
  • 49:13a set of data just,
  • 49:16very, very recently
  • 49:18where we
  • 49:19have data on the
  • 49:22students' performance
  • 49:24who are taught
  • 49:25by teachers
  • 49:27randomly assigned
  • 49:28to our well-being training compared
  • 49:30to teachers randomly assigned to
  • 49:32the control group. And,
  • 49:34for students who start off,
  • 49:37at a more disadvantaged
  • 49:39level,
  • 49:41When they are taught by
  • 49:43teachers who are randomly assigned
  • 49:45to the well-being training, those
  • 49:47students perform significantly
  • 49:49better
  • 49:50on standardized
  • 49:52math tests.
  • 49:53These are statewide
  • 49:55standardized tests compared to students
  • 49:57taught by teachers
  • 49:58randomly assigned to the control
  • 50:00group.
  • 50:01And so this is the
  • 50:03first time
  • 50:04that we know of that
  • 50:06this kind of ripple effect
  • 50:09has been demonstrated
  • 50:10rigorously,
  • 50:11empirically,
  • 50:12and, we're super excited about
  • 50:15these findings,
  • 50:16and,
  • 50:18they will be published soon.
  • 50:20But in another study, which
  • 50:22has just been published, we've
  • 50:23shown,
  • 50:24this is a study that
  • 50:25we did before COVID where
  • 50:27we train teachers in this,
  • 50:31using this approach. We follow
  • 50:32them during COVID, and we
  • 50:34ask the simple question, how
  • 50:35many of you are still
  • 50:36teaching full time
  • 50:38three years later? And we
  • 50:39find that teachers randomly assigned
  • 50:41to our well-being training are
  • 50:43six times more likely to
  • 50:45still be teaching,
  • 50:46three years later compared to
  • 50:48those assigned to a control
  • 50:50group,
  • 50:51and,
  • 50:52doing a cost benefit analysis
  • 50:54based on retention data alone
  • 50:56for each dollar invested in
  • 50:58an intervention.
  • 50:59Three years later, there's the
  • 51:00three dollar and thirty four
  • 51:02cent return on that investment
  • 51:04three years later.
  • 51:06So let me end by
  • 51:08saying we view this as
  • 51:09an urgent public health need.
  • 51:11One of the things that
  • 51:13I often,
  • 51:14remind
  • 51:16us of is that when
  • 51:17we all first evolved as
  • 51:19humans, none of us were
  • 51:20brushing our teeth.
  • 51:22And all of us now
  • 51:23spend a few minutes every
  • 51:24day, virtually every human being
  • 51:26on the planet, brushing their
  • 51:27teeth.
  • 51:29This is not part of
  • 51:30our genome. This is something
  • 51:31we've learned to do.
  • 51:33And the data show that
  • 51:34if we spend even as
  • 51:36short a time as we
  • 51:37spend each day brushing our
  • 51:38teeth, nourishing our mind, this
  • 51:40world would really be a
  • 51:42different place.
  • 51:44So please join us on
  • 51:45this journey
  • 51:46where we can change the
  • 51:47world by nourishing our mind.
  • 51:49And let me end with
  • 51:51a quote from the Dalai
  • 51:52Lama himself,
  • 51:53where he said in his
  • 51:55book, The Art of Happiness,
  • 51:57the systematic training of the
  • 51:58mind, the cultivation of happiness,
  • 52:01the genuine inner transformation
  • 52:03by deliberately selecting and focusing
  • 52:06on positive mental states and
  • 52:08challenging negative mental states
  • 52:10is possible because the very
  • 52:12structure and function of the
  • 52:13brain.
  • 52:14But the wiring in our
  • 52:15brains is not static,
  • 52:17not irrevocably
  • 52:18fixed.
  • 52:19Our brains
  • 52:20are also
  • 52:21adaptable.
  • 52:22Thank you very much.