Neera Dahl, MD, PhD
Professor AdjunctCards
Appointments
Additional Titles
Director, Nephrology Clinical Trials Program, Nephrology
Medical Director, Outpatient Dialysis, Nephrology, DaVita New Haven
Contact Info
Appointments
Additional Titles
Director, Nephrology Clinical Trials Program, Nephrology
Medical Director, Outpatient Dialysis, Nephrology, DaVita New Haven
Contact Info
Appointments
Additional Titles
Director, Nephrology Clinical Trials Program, Nephrology
Medical Director, Outpatient Dialysis, Nephrology, DaVita New Haven
Contact Info
About
Titles
Professor Adjunct
Director, Nephrology Clinical Trials Program, Nephrology
Positions outside Yale
Medical Director, Outpatient Dialysis, Nephrology, DaVita New Haven
Biography
Dr. Dahl has expertise in diagnosis and management of inherited (or genetically based) kidney disease. Her main focus has been ADPKD and other cystic kidney diseases which mimic ADPKD. She is the medical director of the New Haven DaVita unit providing in center hemodialysis, home hemodialysis and peritoneal dialysis. She is the Director of the Nephrology Clinical Trials program overseeing studies in ADPKD, diabetes and hypertension. In collaboration with Dr. Dinesh Singh she runs the Yale Kidney Stone Clinic.
Appointments
Nephrology
Professor AdjunctPrimary
Other Departments & Organizations
- Chronic Kidney Disease Program
- Internal Medicine
- Nephrology
- Prostate & Urologic Cancers Program
- Yale Cancer Center
- Yale Ventures
Education & Training
- Fellow
- Beth Israel Deaconess Medical Center (2002)
- Resident
- Beth Israel Deaconess Medical Center (1999)
- Intern
- BIDMC, Harvard Medical School (1997)
- PhD
- Tufts University (1996)
- MD
- Tufts University School of Medicine (1996)
- BA
- Johns Hopkins University (1987)
- Postdoctoral, PhD
- Tufts University School of Medicine and Sackler School of Biomedical Science
Research
Overview
In collaboration with Dr. Tinika Montgomery (nephrology), Drs. Dinesh Singh, Piruz Motamedinia, and Tim Tran (urology) we have created a Kidney Stone Registry to track important aspects of kidney stone management.
In the inherited kidney disease space I am most interested in those aspects of clinical research which improve care for ADPKD patients.
Medical Subject Headings (MeSH)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Cassius Iyad Ochoa Chaar, MD, MPH, MS, RPVI
Gilbert Moeckel, MD, PhD, FASN
Stefan Somlo, MD
Whitney Besse, MD
Abinet Aklilu, MD, MPH
Margaret Bia, MD
Kidney Diseases
Nephrology
Publications
2024
Clinical Genetic Testing in Nephrology: Core Curriculum 2024
Aron A, Dahl N. Clinical Genetic Testing in Nephrology: Core Curriculum 2024. American Journal Of Kidney Diseases 2024, 84: 632-645. PMID: 39340488, DOI: 10.1053/j.ajkd.2024.05.011.Peer-Reviewed Original ResearchAltmetricConceptsClinical genetic testingGenetic testingRoutine diagnostic workup of patientsKidney diseaseDiagnostic workup of patientsDiagnostic yield of testingRoutine diagnostic workupWorkup of patientsRoutine nephrology careYield of testingGenetic resultsImprove careCore curriculumReduce barriersDiagnostic odysseyExtrarenal manifestationsDiagnostic yieldMonogenic etiologyPatient selectionReduce anxietyPatient populationNephrology careTreatment planningFamily planningSecondary findingsProtein Intake and High Uric Acid Stone Risk
Montgomery T, Nair H, Phadke M, Morhardt E, Ludvigson A, Motamedinia P, Singh D, Dahl N. Protein Intake and High Uric Acid Stone Risk. Kidney Medicine 2024, 6: 100878. PMID: 39279882, PMCID: PMC11399574, DOI: 10.1016/j.xkme.2024.100878.Peer-Reviewed Original ResearchConceptsUric acid stone formersKidney stone formersUric acid stone formationStone formersChronic kidney diseaseStone analysisProtein intakeRetrospective studyKidney functionKidney diseaseAssociated with protein intakeUric acidStone formationLow urine citrateDietary protein intakeDiminished kidney functionProtein catabolic rateBody mass indexUrine urea nitrogenUric acid nephrolithiasisChi-square testPrevalence of uric acid nephrolithiasisUrine citrateNephrology clinicMass indexCKD Risk Stratification
Chebib F, Dahl N. CKD Risk Stratification. Journal Of The American Society Of Nephrology 2024, 35: 1146-1148. PMID: 39053619, PMCID: PMC11387029, DOI: 10.1681/asn.0000000000000455.Peer-Reviewed Original ResearchAltmetricAdvancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group
Franceschini N, Feldman D, Berg J, Besse W, Chang A, Dahl N, Gbadegesin R, Pollak M, Rasouly H, Smith R, Winkler C, Gharavi A, Group N, Ars E, Bekheirnia M, Bier L, Bleyer A, Fuller L, Halbritter J, Harris P, Kiryluk K, Knoers N, Kopp J, Kramer H, Lagas S, Lieske J, Lu W, Mannon R, Markowitz G, Moe O, Nadkarni G, Nast C, Parekh R, Pei Y, Reed K, Rehm H, Richards D, Roberts M, Sabatello M, Salant D, Sampson M, Sanna-Cherchi S, Santoriello D, Sedor J, Sneddon T, Watnick T, Wilfond B, Williams W, Wong C. Advancing Genetic Testing in Kidney Diseases: Report From a National Kidney Foundation Working Group. American Journal Of Kidney Diseases 2024 PMID: 39033956, DOI: 10.1053/j.ajkd.2024.05.010.Peer-Reviewed Original ResearchAltmetricConceptsGenetic testingAllied health professionalsImplementation of genetic testingModified Delphi processChronic kidney diseaseScreening of kidney diseasesHealth professionalsWorking GroupKidney diseaseGenetic risk factorsDelphi processWorking group of expertsNational Kidney FoundationPolygenic causeDisease of multiple causesClinical decisionsRisk factorsGroup of expertsCause of kidney diseaseKidney FoundationGenetic basisMultiple causesGroup consensusGenetic causeMonogenic disordersBiomarkers of Kidney Disease Progression in ADPKD
Ghanem A, Borghol A, Debeh F, Paul S, AlKhatib B, Harris P, Garimella P, Hanna C, Kline T, Dahl N, Chebib F. Biomarkers of Kidney Disease Progression in ADPKD. Kidney International Reports 2024, 9: 2860-2882. PMID: 39435347, PMCID: PMC11492289, DOI: 10.1016/j.ekir.2024.07.012.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAutosomal dominant polycystic kidney diseaseDominant polycystic kidney diseaseKidney disease progressionPolycystic kidney diseaseDisease progressionMonogenic kidney disorderKidney diseaseHeight-adjusted total kidney volumeDisease severityTotal kidney volumePKD1 geneGlomerular filtration rateMayo imaging classificationBody mass indexPersonalized treatment strategiesIncreased kidney sizePathogenic variantsEfficacy of treatmentAssess disease severityTotal cyst volumeGenetic profileImprove patient outcomesPredictive biomarkersCyst volumeKidney volumeKidney Stones Account for Increased Imaging Studies in Autosomal Dominant Polycystic Kidney Disease
Simmons K, Ullman L, Dahl N. Kidney Stones Account for Increased Imaging Studies in Autosomal Dominant Polycystic Kidney Disease. Kidney360 2024, 5: 707-714. PMID: 38526140, PMCID: PMC11146651, DOI: 10.34067/kid.0000000000000424.Peer-Reviewed Original ResearchAltmetricConceptsAbdominal imaging studiesChronic kidney diseaseADPKD patientsImaging studiesKidney stonesChronic kidney disease controlKidney diseaseChronic kidney disease groupIncreased incidence of kidney stonesChronic kidney disease populationChronic kidney disease stagePreserved renal functionRetrospectively reviewed patientsAutosomal dominant polycystic kidney diseaseIncidence of kidney stonesDominant polycystic kidney diseaseChi-square and t-testsCoronary artery diseasePolycystic kidney diseaseCompared to controlsCyst complicationsRenal functionChart reviewLower BMIManual chart reviewPain and Health-Related Quality of Life in Autosomal Dominant Polycystic Kidney Disease: Results from a National Patient-Powered Registry
Hoover E, Holliday V, Merullo N, Oberdhan D, Perrone R, Rusconi C, Park M, Phadnis M, Thewarapperuma N, Dahl N. Pain and Health-Related Quality of Life in Autosomal Dominant Polycystic Kidney Disease: Results from a National Patient-Powered Registry. Kidney Medicine 2024, 6: 100813. PMID: 38689835, PMCID: PMC11059322, DOI: 10.1016/j.xkme.2024.100813.Peer-Reviewed Original ResearchCitationsAltmetricConceptsHealth-related quality of lifeQuality of lifeHRQoL toolsOutcomes health-related quality of lifeDisease-specific assessment toolsHealth care accessCore outcome domainsDisease-specific patientHealth-related qualityBurden of painCross-sectional assessmentHRQoL modulePositive HRQoLPain interferenceCare accessHealthcare accessPatient experienceConsenting participantsCore questionnaireOutcome domainsImpact ScalePain severityEmotional distressHRQoLPatient reportsWhat is the Appropriate Dose of Tolvaptan in ADPKD?
Dahl N, Torres V. What is the Appropriate Dose of Tolvaptan in ADPKD? Kidney International Reports 2024, 9: 737-739. PMID: 38765581, PMCID: PMC11101796, DOI: 10.1016/j.ekir.2024.01.049.Peer-Reviewed Original ResearchCitationsAltmetric
2023
Beyond Loss of Kidney Function: Patient Care in Autosomal Dominant Polycystic Kidney Disease
Hogan M, Simmons K, Ullman L, Gondal M, Dahl N. Beyond Loss of Kidney Function: Patient Care in Autosomal Dominant Polycystic Kidney Disease. Kidney360 2023, 4: 1806-1815. PMID: 38010035, PMCID: PMC10758524, DOI: 10.34067/kid.0000000000000296.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAutosomal dominant polycystic kidney diseaseDominant polycystic kidney diseasePolycystic kidney diseaseKidney diseaseKidney Disease Improving Global Outcomes guidelinesGlobal Outcomes (KDIGO) guidelinesInitiation of RRTSuccessful kidney transplantEvidence-based guidelinesCurrent clinical practiceKidney stone managementMajor morbidityCardiac manifestationsKidney transplantOutcomes guidelinesKidney functionDepression screeningDisease benefitPancreatic cystsSpecialized careRoutine managementClinical practicePatient careStone managementDisease aspectsThe VUS Challenge in Cystic Kidney Disease: A Case-Based Review
Aklilu A, Gulati A, Kolber K, Yang H, Harris P, Dahl N. The VUS Challenge in Cystic Kidney Disease: A Case-Based Review. Kidney360 2023, 5: 152-159. PMID: 37962562, PMCID: PMC10833605, DOI: 10.34067/kid.0000000000000298.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAutosomal dominant polycystic kidney diseaseKidney diseaseHigh pre-test probabilityGenetic testingCase-based reviewPre-test probabilityDominant polycystic kidney diseaseRoutine genetic testingPost-test genetic counselingCystic kidney diseasePolycystic kidney diseaseFurther family studiesNephrology clinicKidney failureClinical criteriaCystic disordersOrdering clinicianCommon causeAppropriate carePathogenic variantsACMG guidelinesClinical settingDiagnostic groupingsUncertain significanceGenetic reports
Clinical Trials
Current Trials
Genetic Determinants of Aneurysms in Autosomal Dominant Polycystic Kidney Disease
HIC ID2000029350RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting ParticipantsGenderBothAge18+ yearsScreening In Anticipation of Future Research
HIC ID2000021443RoleSub InvestigatorPrimary Completion Date12/31/2022Recruiting ParticipantsGenderBothAge2 years - 17 yearsGenetic Studies of Polycystic Livers
HIC ID0003010983RoleSub InvestigatorPrimary Completion Date04/01/2024Recruiting ParticipantsGenderBothAge18+ years
Academic Achievements & Community Involvement
activity Scientific Advisory Board
Advisory BoardsAdvisorDetailsPKD Foundationinvolved in grant review and patient outreach projects with the PKD Foundation10/01/2018 - Presentactivity Medical Review Board
Advisory BoardsBoard MemberDetailsESRD Network of New EnglandHelped determine focus of the ESRD Network projects10/01/2015 - Presentactivity National Kidney Foundation, CT Chapter
Advisory BoardsBoard MemberDetailsNational Kidney Foundation10/01/2008 - Presentactivity American Journal of Kidney Disease
Journal ServiceReviewerDetails2007 - Presentactivity Clinical Journal of the American Society of Nephrology
Journal ServiceReviewerDetails2007 - Present
News
News
- February 15, 2024
Hybrid Approach to Arteriovenous Fistula Aneurysm Repair
- July 13, 2023
Support System, Consistency Important For Dialysis Patients During Pandemic (Discoveries & Impact July 2023)
- December 19, 2022
Yale Named Center of Excellence by Polycystic Kidney Disease (PKD) Foundation
- November 12, 2022Source: Web MD
Talking to Your Kids About ADPKD