2025
Proportion of Obesity-Related Conditions Attributable to Obesity in US Adolescents and Young Adults
Chetty A, Chen A, Hajduk A, Sharifi M, Nugent J. Proportion of Obesity-Related Conditions Attributable to Obesity in US Adolescents and Young Adults. American Heart Journal 2025, 290: 28-29. DOI: 10.1016/j.ahj.2025.07.065.Peer-Reviewed Original ResearchPopulation attributable fractionBody mass indexObesity-related conditionsYoung adultsUS youthNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveyUS adolescentsNutrition Examination SurveyComplex survey methodsNormal body mass indexPrevalence of obesityCross-sectional studyAttributable fractionExamination SurveyNHANES cyclesInsurance statusType 2 diabetesRelative riskLiver steatosisMass indexLogistic regressionAge categoriesObesityExclusion criteriaThe Cost-Effectiveness of Semaglutide and Tirzepatide for Patients With Knee Osteoarthritis and Obesity.
Betensky D, Smith K, Katz J, Yang C, Hunter D, Collins J, Feldman C, Messier S, Kim J, Selzer F, Paltiel A, Losina E. The Cost-Effectiveness of Semaglutide and Tirzepatide for Patients With Knee Osteoarthritis and Obesity. Annals Of Internal Medicine 2025 PMID: 40953447, DOI: 10.7326/annals-24-03609.Peer-Reviewed Original ResearchQuality-adjusted life yearsBody mass indexIncremental cost-effectiveness ratioKnee osteoarthritisWestern Ontario and McMaster Universities Osteoarthritis Index pain scorePain reductionBaseline body mass indexQuality-adjusted life year thresholdsHealth benefitsMicrosimulation modelWeight loss strategiesCost-effectiveMean body mass indexUsual careHealth policyCost-effectiveness thresholdOsteoarthritis Policy ModelCost-effectiveness ratioGlucagon-like peptide-1 receptor agonistsPeptide-1 receptor agonistsLife yearsBase-case cohortMass indexLoss strategiesMedical costsStudy protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa
Heinsberg L, Loia M, Tasele S, Faasalele-Savusa K, Carlson J, Anesi S, Desobry K, Yuchongco E, Guevara B, Sesaga A, Iloilo A, Tofaeono V, Bryan K, Tauasosi-Posiulai T, Kershaw E, Conley Y, Weeks D, Hawley N, Muasau-Howard B. Study protocol for the Health Outcomes in Pregnancy and Early Childhood (HOPE) Study: A mother-infant study in American Samoa. PLOS ONE 2025, 20: e0326644. PMID: 40952996, PMCID: PMC12435730, DOI: 10.1371/journal.pone.0326644.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusBody mass indexHealth outcomesBurden of gestational diabetes mellitusLower risk of type 2 diabetesAmerican Samoa Department of HealthAssociated with higher body mass indexLow riskGestational diabetes statusRisk of type 2 diabetesHigher Body Mass IndexCord blood DNA methylationLongitudinal cohort studyDepartment of HealthInfant body sizePacific IslandersPeer-reviewed publicationsType 2 diabetesBlood DNA methylationInstitutional review boardAmerican SamoaPregnant womenInfant growthFollow-upMass indexEffects of Age and BMI on Histamine H3 Receptor Availability in Healthy Humans
Yang Y, Ibrahim W, Gravel P, Pittman B, Hoye J, Cool R, Sadabad F, Zheng M, Pittenger C, Gallezot J, Carson R, Huang H, Radhakrishnan R, Matuskey D. Effects of Age and BMI on Histamine H3 Receptor Availability in Healthy Humans. Molecular Imaging And Biology 2025, 1-7. PMID: 40938339, DOI: 10.1007/s11307-025-02047-8.Peer-Reviewed Original ResearchHigh-resolution research tomographBody mass indexPositron emission tomographyEffects of ageAnterior cingulate cortexPotential confounding effects of ageAge-related declineTwo-tissue compartment modelCingulate cortexReceptor availabilityFrontal cortexParietal cortexOlfactory cortexSubcortical regionsHealthy humansRegional VTCortexConfounding effects of ageCerebellum cortexEmission tomographyTwo-tissueMass indexHealthy individualsInsulaAssessed alterationsFactors associated with the adoption of the WHO Package of Essential Non-Communicable Diseases (PEN) Protocol 1 in primary healthcare settings in Nepal: a cross-sectional study
Timalsena D, Nakarmi C, Mali S, Dhakal A, Bharati A, Bishwokarma A, Adhikari A, Poudel B, Kulung B, Baral P, Bhattarai S, Dixit L, Pokharel Y, Rhodes E, Xu D, Spiegelman D, Shrestha A. Factors associated with the adoption of the WHO Package of Essential Non-Communicable Diseases (PEN) Protocol 1 in primary healthcare settings in Nepal: a cross-sectional study. BMJ Open 2025, 15: e090923. PMID: 40935428, DOI: 10.1136/bmjopen-2024-090923.Peer-Reviewed Original ResearchConceptsWHO packageNon-communicable diseasesPrimary healthcareBody mass indexCardiovascular disease risk-prediction chartsHealthcare workersCardiovascular diseaseRisk prediction chartsPrimary healthcare settingsPrimary healthcare facilitiesPrimary healthcare centresBlood glucose screeningCardiovascular disease riskLow-resource settingsCross-sectional studyAssociated with accessBMI assessmentHealthcare settingsSystemic barriersProvider motivationBlood pressure measurementsAvailability of metforminRisk chartsPrediction chartsHealthcare facilitiesExploring seasonal fluctuations in dopamine D2/D3 receptor availability in healthy adults: A [11C]PHNO imaging study
Mayeli M, Gallezot J, Cosgrove K, Potenza M, Carson R, Matuskey D. Exploring seasonal fluctuations in dopamine D2/D3 receptor availability in healthy adults: A [11C]PHNO imaging study. Journal Of Affective Disorders 2025, 393: 120293. PMID: 40930176, DOI: 10.1016/j.jad.2025.120293.Peer-Reviewed Original ResearchDopamine D2/D3 receptor availabilityD2/D3 receptor availabilityReceptor availabilityPositron emission tomographyPositron emission tomography ligandsReceptor imaging studiesHealthy adultsImaging studiesDopaminergic markersCognitive performanceSymptomatic fluctuationsMixed-effects analysisScan dateDopamineHealthy participantsDaylight exposureBody mass indexMotor controlEmission tomographyMixed-effectsMixed-effects modelsMass indexGroup participantsSchool of MedicineHealthy individualsImpact of Childhood Neighborhood Deprivation on White Matter and Functional Connectivity During Adolescence
Acosta‐Rodriguez H, Bobba P, Stephan A, Zeevi T, Malhotra A, Tran A, Kaltenhauser S, Ment L, Payabvash S. Impact of Childhood Neighborhood Deprivation on White Matter and Functional Connectivity During Adolescence. Journal Of Neuroimaging 2025, 35: e70087. PMID: 40916058, DOI: 10.1111/jon.70087.Peer-Reviewed Original ResearchConceptsArea Deprivation IndexNeighborhood deprivationSocioeconomic determinantsNeighborhood socioeconomic disadvantageAdult health outcomesPoor neighborhoodsBody mass indexDeprivation indexSocioeconomic disadvantageAdolescent Brain Cognitive Development StudyHealth outcomesDeprived neighbourhoodsFollow-upRepresentative cohortDemographically representative cohortCognitive Development StudyMass indexParental educationWM microstructural integrityChildhood developmentChildhood neighborhoodIncome levelPreadolescent brainSample sizePhysical environmentGenetically determined body mass index is associated with diffuse large B‐cell lymphoma in polygenic and Mendelian randomization analyses
Moore A, Kane E, Teras L, Machiela M, Arias J, Panagiotou O, Monnereau A, Doo N, Wang Z, Slager S, Vermeulen R, Vajdic C, Smedby K, Spinelli J, Vijai J, Giles G, Link B, Arslan A, Nieters A, Bracci P, Camp N, Salles G, Cozen W, Hjalgrim H, De Vivo I, Adami H, Albanes D, Becker N, Benavente Y, Bisanzi S, Boffetta P, Brennan P, Brooks‐Wilson A, Canzian F, Clavel J, Conde L, Cox D, Curtin K, Foretova L, Ghesquières H, Glimelius B, Habermann T, Hofmann J, Lan Q, Liebow M, Lincoln A, Maynadie M, McKay J, Melbye M, Miligi L, Milne R, Molina T, Morton L, North K, Offit K, Padoan M, Piro S, Patel A, Purdue M, Ravichandran V, Riboli E, Severson R, Southey M, Staines A, Tinker L, Travis R, Wang S, Weiderpass E, Weinstein S, Zheng T, Chanock S, Rothman N, Birmann B, Cerhan J, Berndt S. Genetically determined body mass index is associated with diffuse large B‐cell lymphoma in polygenic and Mendelian randomization analyses. International Journal Of Cancer 2025 PMID: 40910475, DOI: 10.1002/ijc.70039.Peer-Reviewed Original ResearchWaist-to-hip ratioBody mass indexDiffuse large B-cell lymphomaMendelian randomization analysisRisk of diffuse large B-cell lymphomaWaist-to-hipNon-Hodgkin's lymphomaGenome-wide association studiesNon-Hodgkin lymphoma subtypesLarge B-cell lymphomaRandomization analysisGenome-wide association studies of European ancestryB-cell lymphomaStudies of European ancestryMass indexAssociated with non-Hodgkin lymphomaAssociated with diffuse large B-cell lymphomaNo significant associationPolygenic scoresMarginal zone lymphomaChronic lymphocytic leukemiaEuropean ancestrySignificant associationRisk factorsFollicular lymphomaThe prevalence of endometriosis in adult female patients with hidradenitis suppurativa: a cross-sectional study using the All of Us Research Programme
Hodelin C, Cohen J, Eisenstein A. The prevalence of endometriosis in adult female patients with hidradenitis suppurativa: a cross-sectional study using the All of Us Research Programme. Clinical And Experimental Dermatology 2025, llaf395. PMID: 40898779, DOI: 10.1093/ced/llaf395.Peer-Reviewed Original ResearchOdds ratioUS National InstitutesHidradenitis suppurativaCross-sectional studyUS National Institutes of HealthBody mass indexNational Institutes of HealthInstitutes of HealthNational InstituteType 2 diabetes mellitusSmoking statusPrevalence of endometriosisAdult female patientsMass indexPolycystic ovarian syndromeFemale patientsUS databaseProgram databaseOvarian syndromeAge rangeEndometriosisHidradenitisResearch programmeYearsOddsAssociation of Adiposity Markers, Serum 25-Hydroxyvitamin D, and Frailty in Older Adults: A Prospective Cohort Study
Wang X, Zhong W, Chen Z, Song W, You F, Li Z, Lv Y, Liu D, Shi X, Mao C. Association of Adiposity Markers, Serum 25-Hydroxyvitamin D, and Frailty in Older Adults: A Prospective Cohort Study. American Journal Of Clinical Nutrition 2025 PMID: 40876539, DOI: 10.1016/j.ajcnut.2025.08.013.Peer-Reviewed Original ResearchWeight-adjusted waist indexAssociated with frailty riskBody roundness indexAdiposity markersFrailty riskOlder adultsProspective cohort studyFrailty indexCohort studyHigh frailty riskSerum 25-hydroxyvitamin DWaist indexRoundness indexSerum 25(OH)DBody shape indexAssociation of adiposityFollow-upBody mass indexFrailty preventionJoint associationsWaist circumferenceBiomarkers Cohort StudyHealth deficitsLinear mixed modelsLow serum 25(OH)DInternational Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm
Duffy G, Oikonomou E, Easton N, Usuku H, Patel J, Katsumata Y, Yamasawa D, Stern L, Goto S, Tsujita K, Cheng P, Khera R, Ahmad F, Ouyang D. International Validation of Echocardiographic Artificial Intelligence Amyloid Detection Algorithm. JACC Advances 2025, 102067. PMID: 40965401, DOI: 10.1016/j.jacadv.2025.102067.Peer-Reviewed Original ResearchPositive predictive valueCardiac amyloidosisReceiver operating characteristic curveArea under the receiver operating characteristic curveOperating characteristics curvePredictive valueDiagnosis of cardiac amyloidosisAccurate diagnosisRetrospective case-control studyGlobal longitudinal strainLeft ventricular wall thicknessNegative predictive valueDiagnosis of CACharacteristic curveVentricular wall thicknessBody mass indexParasternal long axisTransthoracic echocardiographic measurementsCase-control studyCA patientsVentricular hypertrophyEchocardiographic measurementsEchocardiogram studyCA subtypesMass indexA Prospective Assessment of Weight Bias Internalization in Patients Seeking Body Contouring after Bariatric Surgery
Dunford A, Metzler A, Ivezaj V, Pittman B, Alperovich M, Price G. A Prospective Assessment of Weight Bias Internalization in Patients Seeking Body Contouring after Bariatric Surgery. Surgery For Obesity And Related Diseases 2025 PMID: 40940272, DOI: 10.1016/j.soard.2025.06.020.Peer-Reviewed Original ResearchEating-disorder psychopathologyWeight bias internalizationDepressive symptomsAssociated with greater eating-disorder psychopathologyAssociated with eating-disorder psychopathologyHigher weight bias internalizationBody contouring surgeryBody mass indexMental health concernsBariatric surgeryPsychopathologyGroup differencesFollow-upSignificant groupBody imageProspective analysisProspective assessmentTime interactionIndependent of body mass indexWeight lossSymptomsUnited States METHODSContouring surgeryParticipantsBariatric teamImpact of a Weight Loss Intervention on 1-Year Weight Change in Women With Stage II/III Breast Cancer
Ligibel J, Ballman K, McCall L, Goodwin P, Alfano C, Bernstein V, Crane T, Delahanty L, Frank E, Hahn O, Hershman D, Hopkins J, Irwin M, Mayer E, Minasian L, Nebeling L, Neuhouser M, Paskett E, Spears P, Stearns V, Thomson C, Weiss A, White J, Wadden T, Winer E, Hudis C, Partridge A, Carey L. Impact of a Weight Loss Intervention on 1-Year Weight Change in Women With Stage II/III Breast Cancer. JAMA Oncology 2025, 11 PMID: 40839373, PMCID: PMC12371550, DOI: 10.1001/jamaoncol.2025.2738.Peer-Reviewed Original ResearchWeight loss interventionBody mass indexWeight loss trialBreast cancerSecondary analysisLoss trialMenopausal statusRandomized clinical trialsTime-by-group interactionFactors associated with weight changeBaseline body weightPoor quality of lifeWeight changeAge of participantsPoor qualityHigh riskQuality of lifeScalable interventionsNon-HispanicHealth educationHispanic participantsLinear mixed-effects modelsPremenopausal participantsControl groupPostmenopausal participantsExcessive daytime sleepiness and mortality: racial/ethnic variations in a large cohort of veterans
Maghsoudi A, Azarian M, Razjouyan J, Hirshkowitz M, Kryger M, Dashti M, Ramezani A, Sharafkhaneh A. Excessive daytime sleepiness and mortality: racial/ethnic variations in a large cohort of veterans. Sleep Medicine 2025, 135: 106752. PMID: 40865361, DOI: 10.1016/j.sleep.2025.106752.Peer-Reviewed Original ResearchConceptsAll-Cause MortalityBody mass indexRace/ethnic groupsRacial/ethnic groupsCharlson Comorbidity IndexAssociated with all-cause mortalityHealth care systemAssociated with higher all-cause mortalityCohort of veteransMarkers of healthMean body mass indexExcessive daytime sleepinessVeteran recordsCare systemRacial/ethnic variationOdds ratioBlack individualsMass indexEligibility criteriaEffect sizeVeteransStudy findingsComorbidity indexOutcome differencesEthnic groupsMilitary-Related Weight Stigma Prospectively Predicts Dietary Restraint during Pregnancy in U.S. Military Active-Duty Service Members: A Longitudinal Observational Study
Thompson K, Bauman V, Schrag R, White M, Mains A, Rioux S, Spinner H, Thorstad I, Thomas V, Klein D, Haigney M, Tanofsky-Kraff M, Lavender J. Military-Related Weight Stigma Prospectively Predicts Dietary Restraint during Pregnancy in U.S. Military Active-Duty Service Members: A Longitudinal Observational Study. Journal Of The Academy Of Nutrition And Dietetics 2025 PMID: 40825474, DOI: 10.1016/j.jand.2025.08.003.Peer-Reviewed Original ResearchActive-duty service membersWeight stigmaLongitudinal observational studyService membersBody mass indexAssociated with lower diet qualityFood cravingsPast-yearPre-pregnancy body mass indexBody composition standardsLower diet qualityEating behaviorsWeeks gestationObservational studyDietary restraintSources of stigmaGestational weight gainResponses to stigmaUS military service membersWeight stigma experiencesMilitary service membersStigma experiencesExcess energy intakeDiet qualityFood Craving InventoryExcessive gestational weight gain associated with higher risk of cesarean delivery across body mass index categories in the United States
Mcelfish P, Hawley N, Caldwell A, Selig J, Watson D, Gomez-Pomar E, Andersen J, Kraleti S, White L, Willis D, Langston K, Manning N, Callaghan-Koru J, Porter A, Brown C. Excessive gestational weight gain associated with higher risk of cesarean delivery across body mass index categories in the United States. Journal Of Gynecology Obstetrics And Human Reproduction 2025, 54: 103010. PMID: 40796020, PMCID: PMC12434902, DOI: 10.1016/j.jogoh.2025.103010.Peer-Reviewed Original ResearchRisk of cesarean deliveryPre-pregnancy body mass indexHigher risk of cesarean deliveryBody mass indexBody mass index categoriesCesarean deliveryGestational weight gainExcessive GWGAssociated with higher riskPre-pregnancyNational Center for Health StatisticsExcessive gestational weight gainCenter for Health StatisticsCesarean delivery riskHigher pre-pregnancy body mass indexRate of gestational weight gainMode of birthVital records dataRate of GWGSingleton term birthsJ-shaped relationshipHigh riskCephalic presentationProvider levelHealth StatisticsImpact of demographics on mepolizumab effectiveness in severe asthma: One-year REALITI-A subanalysis (12/12 words)
Chupp G, Heaney L, Pelaia G, Almonacid C, Maxwell A, Zhang L, Alfonso-Cristancho R, Howarth P, Brusselle G. Impact of demographics on mepolizumab effectiveness in severe asthma: One-year REALITI-A subanalysis (12/12 words). The Journal Of Allergy And Clinical Immunology In Practice 2025 PMID: 40780384, DOI: 10.1016/j.jaip.2025.07.049.Peer-Reviewed Original ResearchClinically significant asthma exacerbationsBody mass indexPre-BD FEV<sub>1</sub> (%Maintenance oral corticosteroidsSevere asthmaDemographic/clinical characteristicsObservational studyPost hoc subanalysisAsthma onsetACQ-5 scoresObservational study of adultsAge of asthma onsetOlder ageOlder age of onsetForced expiratory volumeReal-world studyMepolizumab treatmentOral corticosteroidsStudy of adultsSmoker subgroupsACQ-5Eosinophilic phenotypeMepolizumabAge-of-onsetFollow-upRegional and systemic adipose mass and peripheral conduit artery function
Wakeham D, Beckman B, Mashayekhi M, Luther J, Garner E, Perkins B, Gottlieb J, Niswender K, Hearon C, Brown N, Beckman J. Regional and systemic adipose mass and peripheral conduit artery function. Diabetes Research And Clinical Practice 2025, 227: 112408. PMID: 40774652, DOI: 10.1016/j.diabres.2025.112408.Peer-Reviewed Original ResearchConceptsBody mass indexVascular functionInsulin resistanceVisceral adiposityLean massWaist:hip ratioAssociated with body mass indexAssociated with impaired vascular functionTotal body lean massPre-diabetic levelsArm lean massRegional fat massVisceral fat distributionPearson product-moment correlation coefficientTotal body fatBody lean massImpaired vascular functionHigh visceral adiposityProduct-moment correlation coefficientBrachial artery FMDHip ratioArm fatFat massHOMA-IRMatsuda indexBlunted Hemodynamic Response to Pharmacological Stress is Predictive of Mortality in Liver Transplant Candidates
Csecs I, Sharma A, Khungar V, Sinusas A, Possick S, Miller E, Feher A. Blunted Hemodynamic Response to Pharmacological Stress is Predictive of Mortality in Liver Transplant Candidates. Journal Of Nuclear Cardiology 2025, 102454. PMID: 40769316, DOI: 10.1016/j.nuclcard.2025.102454.Peer-Reviewed Original ResearchLiver transplant candidatesMELD scoreAssociated with mortalityRetrospective studyCardiovascular comorbiditiesLiver diseaseMedian follow-up periodTransplant candidatesResponse to pharmacological stressSingle-photon Emission Computed TomographyRegadenoson stress testingEnd-stage liver diseaseIncremental prognostic valueNuclear stress testingRetrospective cohort analysisFollow-up periodChronic liver diseaseBody mass indexCoronary artery diseaseHemodynamic responseStress testEmission Computed TomographyDiastolic blood pressurePredictive of mortalityPositron emission tomographyCash Transfers and Their Effect on Maternal and Young Children’s Health
Duncan G, Magnuson K, Kunin-Batson A, Yoshikawa H, Fox N, Halpern-Meekin S, Ainsworth N, Black S, Nelson J, Nelson T, Georgieff M, Karhson D, Gennetian L, Noble K. Cash Transfers and Their Effect on Maternal and Young Children’s Health. JAMA Pediatrics 2025, 179: 867-875. PMID: 40522644, PMCID: PMC12171960, DOI: 10.1001/jamapediatrics.2025.1612.Peer-Reviewed Original ResearchMonthly unconditional cash transfersBody mass indexHealth of mothersChild healthPhysical healthBMI percentileMental healthMother-infant dyadsUnconditional cash transfersLow-incomeChild body mass indexMental health of mothersMaternal reportPhysical health of mothersChild BMI percentileMaternal mental healthMaternal depressive symptomsChild's fourth birthdayDetect group differencesCash transfersGroup differencesPostpartum wardMother-child dyadsChildren's HealthMinneapolis/St Paul
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply