2025
Demographic Factors and Burnout Outcomes Associated With Disability Status Uncertainty in U.S. Medical Students.
Pereira-Lima K, Meeks L, Nguyen M, Sheets Z, Jain N, Stergiopoulos E, Addams A, Moreland C, Boatright D. Demographic Factors and Burnout Outcomes Associated With Disability Status Uncertainty in U.S. Medical Students. Academic Medicine 2025 PMID: 40550106, DOI: 10.1097/acm.0000000000006128.Peer-Reviewed Original ResearchMedical studentsDisability statusIncreased risk of burnoutStigma-related concernsRisk of burnoutAssociated with significantly greater oddsLegal definition of disabilitySecond-year medical studentsU.S. medical studentsPromote well-beingMultivariate logistic regressionAuthors analyzed dataBurnout outcomesOldenburg Burnout Inventory for Medical StudentsDefinition of disabilityHigh burnoutMedical traineesGreater oddsDemographic associationsCultural barriersLogistic regressionDemographic characteristicsBurnoutDemographic factorsOddsIntravenous thrombolysis for acute ischemic stroke patients with cerebral amyloid angiopathy
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Intravenous thrombolysis for acute ischemic stroke patients with cerebral amyloid angiopathy. Journal Of The Neurological Sciences 2025, 475: 123586. PMID: 40561725, DOI: 10.1016/j.jns.2025.123586.Peer-Reviewed Original ResearchAssociated with significantly higher oddsSignificantly higher oddsHigher oddsMultivariate logistic regressionAcute ischemic stroke patientsIn-Hospital MortalityAcute ischemic strokeLogistic regressionAssociated with higher oddsIntravenous thrombolysisDatabase of hospitalizationsAssociated with older agePropensity score matchingSelf-CareBalanced treatment groupsIschemic stroke patientsIntracerebral hemorrhageHome dischargeStroke patientsSecondary outcomesCerebral amyloid angiopathyPrimary outcomeOddsScore matchingHemorrhagic cerebrovascular diseaseAge, Race, and Ethnicity of Maternal Grandparents in Autism Spectrum Disorder, a California Multigenerational Study
Chow T, Meng Q, Xiao J, O'Sharkey K, Liew Z, Ritz B. Age, Race, and Ethnicity of Maternal Grandparents in Autism Spectrum Disorder, a California Multigenerational Study. Autism Research 2025 PMID: 40542519, DOI: 10.1002/aur.70074.Peer-Reviewed Original ResearchOdds ratioOlder grandparentsBirth cohort studyMother-child pairsHispanic grandmothersASD riskCohort studyInfluence of ageInverse associationWhite raceInvestigate associationsGrandparent ageYounger ageLogistic regressionOlder ageAutism spectrum disorderSpectrum disorderRace/ethnicityAgeOddsRiskMaternal grandparentsGrandparentsDisordersGrandmothersJoint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States.
Chu L, Wang R, Gross C, Wei J, Lu Y, Krumholz H, Ma X, Chen K. Joint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States. Circulation 2025 PMID: 40458867, DOI: 10.1161/circulationaha.124.073614.Peer-Reviewed Original ResearchIncident acute myocardial infarctionAcute myocardial infarctionIncreased oddsRisk of acute myocardial infarctionHigher risk of acute myocardial infarctionProbability of acute myocardial infarctionOccurrence of acute myocardial infarctionRandom-effects meta-analysisCase-crossover studyMultivariate random-effects meta-analysisExposure to ozoneRegion-specific estimatesMyocardial infarctionStatistical interaction termsAmbient ozone pollutionPrevention strategiesUnited StatesJoint exposureMeta-analysisAdult ageYoung adultsHigh riskAdultsOddsInteraction termsNationwide sociodemographic patterns in airborne exposure to probable carcinogens from industrial sources
Pruitt C, Fisher J, Flory A, Graubard B, Ward M, Jones R, Madrigal J. Nationwide sociodemographic patterns in airborne exposure to probable carcinogens from industrial sources. The Science Of The Total Environment 2025, 986: 179674. PMID: 40449360, DOI: 10.1016/j.scitotenv.2025.179674.Peer-Reviewed Original ResearchConceptsWhite populationLow socioeconomic statusCensus tract boundariesHigh school educationInternational Agency for Research on CancerSociodemographic characteristicsSociodemographic groupsSociodemographic predictorsSocioeconomic statusSociodemographic patternsCensus tractsProbable carcinogensLogistic regressionOddsIndustrial air emissionsSchool educationLatinosBlack AmericansTract boundariesEvaluate differencesPrescription Pain Medication Misuse with and Without Heroin Use Among Adolescents: relationships with Routine Healthcare, Family Support, Academic Performance, Violence, and Other Risky Behaviors
Jalilian-Khave L, Stefanovics E, Zhai Z, Potenza M. Prescription Pain Medication Misuse with and Without Heroin Use Among Adolescents: relationships with Routine Healthcare, Family Support, Academic Performance, Violence, and Other Risky Behaviors. Substance Use & Misuse 2025, 60: 1400-1410. PMID: 40383936, PMCID: PMC12187537, DOI: 10.1080/10826084.2025.2499945.Peer-Reviewed Original ResearchConceptsPrescription pain medication misusePain medication misuseFamily supportHealthcare participantsRisky behaviorsHeroin useMedication misuseOpioid misuseYouth Risk Behavior Survey dataPrescription pain medicationBehavior Survey dataRoutine healthcareHealthcare utilizationPublic health crisisChi-square analysisHigher oddsSurvey dataOdds ratioPain medicationHigh school respondentsAdjusted modelsAcademic performanceNegative healthOddsHealth crisisUnraveling the genetics of gulf war illness in diverse participants enrolled in the million veteran program
Pathak G, Koller D, Cabrera-Mendoza B, Nono Djotsa A, Wendt F, De Lillo A, Friligkou E, He J, Kouakou M, Duong L, Vahey J, Steele L, Quaden R, Harrington K, Ahmed S, Gaziano J, Concato J, Zhao H, Radhakrishnan K, Gelernter J, Gifford E, Aslan M, Helmer D, Hauser E, Polimanti R. Unraveling the genetics of gulf war illness in diverse participants enrolled in the million veteran program. Human Molecular Genetics 2025, ddaf075. PMID: 40366759, DOI: 10.1093/hmg/ddaf075.Peer-Reviewed Original ResearchPolygenic scoresGulf War IllnessGenome-wide dataDepression polygenic scoresPhenome-wide analysisDiverse ancestral backgroundsT2D polygenic scoreAssociated with higher oddsGulf War eraPolygenic architectureAncestral backgroundVeteran ProgramChronic conditionsHigher oddsType 2 diabetesGW veteransVeteransDisease pathogenesisDiverse participantsGulf WarOddsPhysical strengthIllnessComprehensive assessmentAnxietyAdolescent Dating Violence and Suicide Planning Among Girls in US High Schools: An Intracategorical Intersectional Analysis by Race and Ethnicity.
Sharpless L, Alvarez K, Kershaw T, Willie T. Adolescent Dating Violence and Suicide Planning Among Girls in US High Schools: An Intracategorical Intersectional Analysis by Race and Ethnicity. American Journal Of Public Health 2025, e1-e9. PMID: 40311098, DOI: 10.2105/ajph.2025.308043.Peer-Reviewed Original ResearchYouth Risk Behavior SurveyUS high schoolsSuicide planOdds of suicide planWeighted Logistic RegressionNationally Representative StudyRisk Behavior SurveyPrevention programsSuicide preventionWhite girlsLogistic regressionRepresentative studyAssess moderationEffect sizeLatina girlsBehavior SurveyGirlsADVPreventionOddsRace/ethnicityHigh schoolHealthy relationshipsSuicidePrevention of sexual violenceFactors Associated with Preoperative Attrition from a Large, Racially and Ethnically Representative Bariatric Program in the USA: A Single-Center Retrospective, Cohort Study
Hamid S, Butensky S, Graetz E, Olivares M, Schwartz J, Schneider E, Ghiassi S, Gibbs K. Factors Associated with Preoperative Attrition from a Large, Racially and Ethnically Representative Bariatric Program in the USA: A Single-Center Retrospective, Cohort Study. Obesity Surgery 2025, 35: 2390-2394. PMID: 40295326, DOI: 10.1007/s11695-025-07884-8.Peer-Reviewed Original ResearchConceptsFactors associated with attritionAssociated with decreased oddsObesity-related diseasesHispanic ethnicitySocial Vulnerability IndexStudy samplePreoperative attritionElectronic health recordsAcademic health systemAssociated with increased oddsAssociated with attritionRegional-level factorsMultivariate logistic regressionHealth recordsNon-HispanicHealth systemCompared individual-US populationIncreased oddsSurgical treatment of obesityCohort studyMedicare insuranceLogistic regressionMedicareOdds139 Assessing the inclusion of women and minority populations in ClinicalTrials.gov results in studies focused on type 2 diabetes and GLP1 drugs
Reynolds J, Barone C, Calvocoressi L. 139 Assessing the inclusion of women and minority populations in ClinicalTrials.gov results in studies focused on type 2 diabetes and GLP1 drugs. Journal Of Clinical And Translational Science 2025, 9: 41-41. PMCID: PMC12050505, DOI: 10.1017/cts.2024.799.Peer-Reviewed Original ResearchType 2 diabetesBlack/African AmericanClinical Trials Transformation InitiativeAfrican American individualsCount of participantsGLP-1Diversity of participantsHispanic ethnicityStudy characteristicsIntervention studiesMinority populationsDiverse populationsAmerican individualsOddsStatistically significant differenceEthnicityMedical advancesGroup comparisonsParticipantsInclusion of womenInfluence of covariatesBaseline countsClinical researchMean ratiosClinical trialsEffects of Tirzepatide in Type 2 Diabetes Individual Variation and Relationship to Cardiometabolic Outcomes
Aminorroaya A, Oikonomou E, Biswas D, Jastreboff A, Khera R. Effects of Tirzepatide in Type 2 Diabetes Individual Variation and Relationship to Cardiometabolic Outcomes. Journal Of The American College Of Cardiology 2025, 85: 1858-1872. PMID: 40368575, PMCID: PMC12186526, DOI: 10.1016/j.jacc.2025.03.516.Peer-Reviewed Original ResearchConceptsElevated body mass indexCardiometabolic abnormalitiesBody mass indexOdds of elevated body mass indexType 2 diabetesIndividual Participant Data Meta-AnalysisMass indexParticipant data meta-analysisOdds of MetSCardiometabolic risk factorsComponents of metabolic syndromeData Meta-AnalysisHigh-density lipoprotein cholesterolCardiometabolic healthStudy design differencesMixed-effects modelsBaseline usePhase 3 randomized clinical trialSodium-glucose cotransporter 2 inhibitorsOddsStudy outcomesEffects of tirzepatideMeta-analysisRisk factorsClinical subpopulationsThe association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries
Smith L, López Sánchez G, Shin J, Oh H, Kostev K, Tully M, Barnett Y, Butler L, Veronese N, Soysal P, Jacob L, Koyanagi A. The association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries. European Journal Of Ageing 2025, 22: 12. PMID: 40107990, PMCID: PMC11923311, DOI: 10.1007/s10433-025-00848-y.Peer-Reviewed Original ResearchFall-related injuriesFall riskChronic conditionsOlder adultsAssociated with increased fall riskChronic physical conditionsCommunity-based dataSelf-reported informationMiddle-income countiesMiddle-income countriesHigh-income countriesMultivariate logistic regressionPhysical multimorbidityMultimorbidityIncreased oddsGlobal ageLMICsLogistic regressionPotential mediatorsMediation analysisAdultsOddsAssociationPhysical conditionsInjurySobering Overview of Traumatic Craniofacial Injuries Involving Drugs and Alcohol: A Comprehensive Analysis of the NEISS Database
Boroumand S, Ajjawi I, Boroumand T, Allam O, Huelsboemer L, Stögner V, Kauke-Navarro M, Haykal S, Alperovich M, Pomahac B. Sobering Overview of Traumatic Craniofacial Injuries Involving Drugs and Alcohol: A Comprehensive Analysis of the NEISS Database. Craniomaxillofacial Trauma & Reconstruction 2025, 18: 13. PMID: 40271459, PMCID: PMC11995830, DOI: 10.3390/cmtr18010013.Peer-Reviewed Original ResearchCraniofacial injuriesTraumatic craniofacial injuriesEmergency departmentOdds of hospital admissionTwo-proportion z-testFrequent presentationNEISS databaseED presentationsIntoxicated patientsCraniofacial anatomyHospital admissionPatientsEpidemiological findingsTraumatic injuryDemographic variablesInjuryDrugDrugs/alcoholContext of drugZ-testInternal injuriesStairs/stepsHematomaAlcoholOddsMedication for Opioid Use Disorder for Hospitalized Patients at Six New York City Public Hospitals with an Addiction Consult Service.
Rostam-Abadi Y, McNeely J, Tarpey T, Fernando J, Appleton N, Fawole A, Mazumdar M, Kalyanaraman Marcello R, Cooke C, Dolle J, Siddiqui S, Schatz D, King C. Medication for Opioid Use Disorder for Hospitalized Patients at Six New York City Public Hospitals with an Addiction Consult Service. Journal Of Addiction Medicine 2025 PMID: 39908531, DOI: 10.1097/adm.0000000000001450.Peer-Reviewed Original ResearchNew York City public hospitalCity public hospitalsAddiction consult servicesPublic hospitalsDrivers of racial disparitiesPopulation-specific barriersElectronic health recordsYears post-implementationOpioid use disorder treatmentMajority of patientsHealth recordsPost-implementationAddiction careOpioid use disorderRacial disparitiesLogistic regressionInpatient departmentConsultation serviceClinical characteristicsEligible patientsMOUDOddsConsultationHospitalized patientsHospitalThe Impact of Medical School Experiences in Global Surgery on Perceptions and Career Plans Among U.S. Medical Students
Kersh L, Serrato P, Anderson C, Raguveer V, Peck C, Ally S, Gondi I, Subhedar S, Rollins A, Hauser B, Jayaram A, Hill S, Wariso B, Rehman S, Alliance G, Clune J. The Impact of Medical School Experiences in Global Surgery on Perceptions and Career Plans Among U.S. Medical Students. Journal Of Surgical Education 2025, 82: 103441. PMID: 39894006, DOI: 10.1016/j.jsurg.2025.103441.Peer-Reviewed Original ResearchConceptsMedical school experienceGlobal surgeryMedical studentsMedical schoolsSurgical mission tripsCross-sectional survey studyAssociated with lower oddsMission tripsAssociated with increased oddsMedical school curriculumGlobal health researchU.S. medical studentsCareer planningSurgery researchGlobal surgery educationResponding medical studentsMultivariate regression modelHealth researchSurgery opportunitiesLower oddsSchool experiencesSurgeryOddsSurgery educationMedical institutionsBidirectional relationship between epigenetic age and stroke, dementia, and late-life depression
Rivier C, Szejko N, Renedo D, Clocchiatti-Tuozzo S, Huo S, de Havenon A, Zhao H, Gill T, Sheth K, Falcone G. Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression. Nature Communications 2025, 16: 1261. PMID: 39893209, PMCID: PMC11787333, DOI: 10.1038/s41467-024-54721-0.Peer-Reviewed Original ResearchThis study shows a bidirectional link between accelerated epigenetic aging and brain health events like stroke, dementia, and depression, supporting new prevention strategies for aging-related conditions.Comparative efficacy and safety of stent retrievers as a bailout strategy following failed contact aspiration technique in acute stroke thrombectomy
Ezzeldin M, Hukamdad M, Kasem R, Ezzeldin R, Maier I, T A, Jabbour P, Kim J, Howard B, Alawieh A, Wolfe S, Starke R, Psychogios M, Shaban A, Goyal N, Dye J, Alaraj A, Yoshimura S, Fiorella D, Tanweer O, Romano D, Navia P, Cuellar H, Fragata I, Polifka A, Mascitelli J, Osbun J, Siddiqui F, Moss M, Limaye K, Mokin M, Matouk C, Park M, Brinjikji W, Daglioglu E, Williamson R, Altschul D, Ogilvy C, Crosa R, Levitt M, Gory B, Grandhi R, Paul A, Kan P, Casagrande W, Chowdhry S, Stiefel M, Chaubal V, Spiotta A. Comparative efficacy and safety of stent retrievers as a bailout strategy following failed contact aspiration technique in acute stroke thrombectomy. Journal Of NeuroInterventional Surgery 2025, jnis-2024-022781. PMID: 39884851, DOI: 10.1136/jnis-2024-022781.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageTrevo stent retrieverContact aspirationStent retrieverAcute ischemic strokeEndovascular thrombectomyRecanalization rateFunctional outcomesAssociated with higher recanalization ratesOdds of symptomatic intracranial hemorrhageHigher recanalization ratesAssociated with higher oddsEndovascular thrombectomy patientsContact aspiration techniqueIntracranial hemorrhageMulticenter registryRecanalizationReduced oddsStroke thrombectomyHigher oddsIschemic strokeThrombectomyAspiration techniqueBailout strategyOdds
2024
The Perceived Impact of Global Surgery Engagement on Career Advancement among US Medical Students
Serrato P, Solaiman R, Vohra H, Hu K, Jain A, Alamdeen Y, Fagla B, Peck C, Hill S, Wariso B, Rehman S, Subhedar S, Kersh L, Anderson C, Clune J, Alliance G. The Perceived Impact of Global Surgery Engagement on Career Advancement among US Medical Students. Journal Of Surgical Education 2024, 82: 103404. PMID: 39740592, DOI: 10.1016/j.jsurg.2024.103404.Peer-Reviewed Original ResearchConceptsAssociated with increased oddsGlobal surgeryResidency applicantsMultivariate logistic regression modelGlobal surgery programsAcademic global surgeryLogistic regression modelsUS medical studentsMultivariate analysisSurgeryMedical studentsSurgery interest groupSurgery programsSurgery trainingPerceived impactCross-sectional survey studyMedical school curriculumSurgeonsMedical institutionsMedical students' perceptionsSurgery participantsHealth equityOddsCareer advancementMedical schoolsIncreasing patient viewership of complex imaging reports: The paradox of the Cures Act
Amin K, Davis M, Naderi A, Forman H. Increasing patient viewership of complex imaging reports: The paradox of the Cures Act. Clinical Imaging 2024, 119: 110398. PMID: 39756146, DOI: 10.1016/j.clinimag.2024.110398.Peer-Reviewed Original ResearchConceptsElectronic health recordsCentury Cures ActCures ActImprove patient experienceRadiology reportsReading grade levelPatient experienceHealth recordsHealth informationRecommended levelsRetrospective observational studyObservational studyPatientsViewing probabilityRadiologyOddsHealthYearsIncrease viewershipReportsGrade levelModalitiesProvisionPredictors of HIV and STI testing among sexually active Black adolescents: Results from YRBSS 2019–2021
Weerakoon S, Srikanth N, Aivadyan C, Takenaka B, Rose R, Rutledge J, Sissoko G, Opara I. Predictors of HIV and STI testing among sexually active Black adolescents: Results from YRBSS 2019–2021. Journal Of HIV/AIDS & Social Services 2024, ahead-of-print: 1-16. DOI: 10.1080/15381501.2024.2435882.Peer-Reviewed Original ResearchSexually transmitted infection testingSexually transmitted infectionsPredictors of HIVE-cigarettesOdds of testingE-cigarette useYouth Risk Behavior Surveillance SystemBehavior Surveillance SystemBlack adolescentsCurrent substance usersCondom useHIVSexual partnersTesting behaviorInfluence testing behaviourPreventive health measuresSubstance usersSubstance useAdolescentsOddsPredictorsRegression modelsAgeSexMale
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