2025
Lived-experience perspectives on the psychological factors linking childhood maltreatment to later intimate partner violence victimization
Phillips A, Williams R, Okuoimose V, Hiller R, McCrory E, Viding E, Pezzoli P. Lived-experience perspectives on the psychological factors linking childhood maltreatment to later intimate partner violence victimization. European Journal Of Psychotraumatology 2025, 16: 2524922. PMID: 40985493, PMCID: PMC12459178, DOI: 10.1080/20008066.2025.2524922.Peer-Reviewed Original ResearchConceptsIntimate partner violence victimizationIntimate partner violenceChildhood maltreatmentIntimate relationshipsPartner violence victimizationMethod:</b>Psychological factorsThreat management strategiesPartner violenceViolence victimizationReflexive thematic analysisSemi-structured interviewsMaltreatmentRelationship dynamicsPerspectives of individualsVictimsSelf-ConceptChildhood experiencesSelf-esteemRelationship patternsQualitative studyThematic analysisUnited KingdomUnmet needsPreventive interventionsChildhood allostatic load predicts cardiometabolic health in adulthood.
Hinz E, Vitali A, Tong G, Pontzer H, Copeland W. Childhood allostatic load predicts cardiometabolic health in adulthood. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2508549122. PMID: 40982685, DOI: 10.1073/pnas.2508549122.Peer-Reviewed Original ResearchConceptsAdult cardiometabolic healthCardiometabolic healthAllostatic loadAL scoreCardiometabolic outcomesChildhood ALCumulative burdenAdult cardiometabolic outcomesWaist-to-hip ratioBurden of chronic stressWaist-to-hipAssociated with C-reactive proteinHealth in adulthoodLong-term health trajectoriesLife course effectsCumulative stress exposureChildhood BMIAge-standardized valuesCardiometabolic indicatorsHealth outcomesHealth trajectoriesPhysiological dysregulationDiastolic blood pressureImputed datasetsCohort studyODAD4-Related Primary Ciliary Dyskinesia: Report of Five Cases and a Founder Variant in Quebec
Bourassa M, Sillon G, Ding S, Chioccioli M, Lek M, Ma K, Mejia-Garcia A, Gravel S, Vinh D, Knowles M, Leigh M, Davis S, Ferkol T, Olivier K, Schecterman E, Yin W, Sears P, Gentzsch M, Boyles S, Bennett W, Zeman K, Ostrowski L, Zariwala M, Shapiro A. ODAD4-Related Primary Ciliary Dyskinesia: Report of Five Cases and a Founder Variant in Quebec. Cells 2025, 14: 1460. PMID: 41002425, PMCID: PMC12468610, DOI: 10.3390/cells14181460.Peer-Reviewed Original ResearchConceptsPrimary ciliary dyskinesiaIn-frame skippingCiliary dyskinesiaChronic oto-sino-pulmonary diseaseOto-sino-pulmonary diseaseNasal nitric oxide levelsMild formOuter dynein arm defectsDevelopment of bronchiectasisDynein arm defectsSkipping of exon 2Nitric oxide levelsReverse transcription polymerase chain reactionPulmonary phenotypePulmonary function valuesTranscription polymerase chain reactionRadiographic pneumoniaPolymerase chain reactionFounder variantPathogenic variantsAbnormal splicingMucociliary clearanceDiagnostic evaluationRespiratory symptomsExon 2Examining harsh parenting as a moderator in the association between childhood irritability and adolescent suicidal behaviors
Rosialda K, Zephirin C, Tseng W, Jha M, Leibenluft E, Orri M. Examining harsh parenting as a moderator in the association between childhood irritability and adolescent suicidal behaviors. Psychological Medicine 2025, 55: e274. PMID: 40958663, DOI: 10.1017/s0033291725000704.Peer-Reviewed Original ResearchConceptsHarsh parentingSuicide attemptsChildhood irritabilitySelf-harmParent ratingsSuicidal behaviorPathway to suicide attemptLevels of harsh parentingRisk of suicide attemptAssociations of irritabilityRisk of self-harmAdolescent suicide attemptersAdolescent suicidal behaviorModerating RoleInterpersonal stressorsChild irritabilityParenting behaviorsSex differencesParenting interventionsSelf-ReportHeightened sensitivitySuicide preventionSuicideIrritation scoresAged 3Epistemic trust towards teacher questionnaire: Development and preliminary validation
Desatnik A, Yakubovskiy M, Tarasov S, Fonagy P. Epistemic trust towards teacher questionnaire: Development and preliminary validation. PLOS ONE 2025, 20: e0331398. PMID: 40953073, PMCID: PMC12435716, DOI: 10.1371/journal.pone.0331398.Peer-Reviewed Original ResearchConceptsEpistemic trustMeasures of teacher—student relationship qualityTeacher-student relationship qualityDiverse educational settingsEvolutionary developmental psychologyHigh school studentsNon-verbal immediacySelf-report measuresThree-factor structurePsychometrically sound instrumentConfirmatory factor analysisStudent motivationEducational contextTeacher questionnairesEducational settingsLearning outcomesEducational psychologySchool studentsWorking allianceFactor structureDevelopmental psychologyPreliminary supportDiscriminant validityGood model fitTeachersThe effect of caffeine use in the relationship between gaming and sleep in adolescents: A mediation analysis.
Park J, Han X, Potenza M, Zhao Y. The effect of caffeine use in the relationship between gaming and sleep in adolescents: A mediation analysis. Journal Of Behavioral Addictions 2025, 14: 1368-1379. PMID: 40928887, DOI: 10.1556/2006.2025.00076.Peer-Reviewed Original ResearchConceptsEffects of caffeine useCaffeine useSleep difficultiesAdolescent Brain Cognitive Development StudyYoung adolescentsCognitive Development StudySleep durationMediation analysisAdolescentsFollow-up dataDaily sleep durationSleepLost sleepYear 2Development studiesCaffeineNegative relationshipPositive relationshipYear 3AdulthoodRelationshipDifficultiesGame performanceHealth guidelinesHealth issuesEstimating the associations between women’s maltreatment in childhood and inflammatory biomarker levels prior to and during pregnancy
Wu B, Vyas C, Medina A, Slopen N, Mahalingaiah S, Chavarro J, Mukherjee R, Weisskopf M, Roberts A. Estimating the associations between women’s maltreatment in childhood and inflammatory biomarker levels prior to and during pregnancy. PLOS ONE 2025, 20: e0331905. PMID: 40920854, PMCID: PMC12416833, DOI: 10.1371/journal.pone.0331905.Peer-Reviewed Original ResearchConceptsTumor necrosis factor alpha receptor 2Associated with higher riskC-reactive proteinAdverse neurodevelopmentInflammatory biomarkersNurses' Health Study 3Risk of adverse neurodevelopmentInterleukin-6Gestational risk factorsMaternal childhood abuseMaternal childhood maltreatmentGeneralized Estimating EquationsSample of well-educatedChronic systemic inflammationInflammatory biomarker levelsChildhood maltreatmentNon-HispanicExposure to maltreatmentPregnant participantsVulnerable populationsOffspring neurodevelopmentSystemic inflammationIFN-gProspective cohortInterferon-gammaImpact of Childhood Neighborhood Deprivation on White Matter and Functional Connectivity During Adolescence
Acosta‐Rodriguez H, Bobba P, Stephan A, Zeevi T, Malhotra A, Tran A, Kaltenhauser S, Ment L, Payabvash S. Impact of Childhood Neighborhood Deprivation on White Matter and Functional Connectivity During Adolescence. Journal Of Neuroimaging 2025, 35: e70087. PMID: 40916058, DOI: 10.1111/jon.70087.Peer-Reviewed Original ResearchConceptsArea Deprivation IndexNeighborhood deprivationSocioeconomic determinantsNeighborhood socioeconomic disadvantageAdult health outcomesPoor neighborhoodsBody mass indexDeprivation indexSocioeconomic disadvantageAdolescent Brain Cognitive Development StudyHealth outcomesDeprived neighbourhoodsFollow-upRepresentative cohortDemographically representative cohortCognitive Development StudyMass indexParental educationWM microstructural integrityChildhood developmentChildhood neighborhoodIncome levelPreadolescent brainSample sizePhysical environmentTopography and environmental deficiencies are associated with chikungunya virus exposure in urban informal settlements in Salvador, Brazil
Travis C, Argibay H, Pellizzaro M, de Oliveira D, Santana R, Palma F, Lustosa R, Santana J, Souza F, López Y, Reis M, Ko A, Diggle P, Ribeiro G, Begon M, Costa F, Khalil H, Eyre M. Topography and environmental deficiencies are associated with chikungunya virus exposure in urban informal settlements in Salvador, Brazil. PLOS Neglected Tropical Diseases 2025, 19: e0013477. PMID: 40911655, PMCID: PMC12440227, DOI: 10.1371/journal.pntd.0013477.Peer-Reviewed Original ResearchConceptsUrban informal settlementsPublic health burdenLow-income communitiesInformal settlementsGlobal public health burdenBinomial mixed-effects modelDegree of urbanisationHealth burdenMixed-effects modelsCHIKV seroprevalenceEnvironmental deficienciesReduced riskAssociated with seropositivityRisk factorsUrban communitiesMale sexBrazilian citiesRiskHouseholdsCommunityCHIKV seropositivityIndividualsEnvironmental factorsExposure patternsDomains individualsAbnormal Puberty and Amenorrhea: A Review.
Garg A, Vash-Margita A, Simoni M. Abnormal Puberty and Amenorrhea: A Review. Pediatric Annals 2025, 54: e294-e301. PMID: 40924007, DOI: 10.3928/19382359-20250707-03.Peer-Reviewed Original ResearchConceptsDelayed pubertyDevelopment of secondary sexual characteristicsSecondary amenorrheaSecondary hypogonadismPrecocious pubertyPeripheral mechanismsSecondary sexual characteristicsTherapeutic approachesHormonal imbalanceClinical assessmentPubertyFemale childrenAmenorrheaNormal onsetAged 8Sexual characteristicsIndividualized careHypogonadismInterstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy
Landazuri P, Cheng J, Leuthardt E, Kim A, Southwell D, Fecci P, Neimat J, Sun D, Lega B, Panov F, Chiang V, Abel T, Ben-Haim S, Piccioni D, Shih J, Palys V, Rodriguez A, Bandt S, Petronio J, Lacroix M, Baumgartner J. Interstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy. JAMA Neurology 2025, 82: 915-924. PMID: 40622685, PMCID: PMC12235534, DOI: 10.1001/jamaneurol.2025.1897.Peer-Reviewed Original ResearchConceptsLaser interstitial thermal therapyDrug-resistant mesial temporal lobe epilepsyMesial temporal lobe epilepsySeizure outcomeInterstitial thermal therapyTemporal lobe epilepsyFollow-upProcedural outcomesSafety dataQuality of lifeLobe epilepsyIntensive care unit timeMonths of follow-upAssociated with seizure outcomeYears of follow-upProspective multicenter registryPostsurgical seizure outcomeMesial temporal sclerosisIntensive care unitThermal therapyQuality of life improvementQuality of life scoresInternational League Against EpilepsyLength of stayMagnetic resonance imagingComparison of dengue, chikungunya, and Zika among children in Nicaragua across 18 years: a single-centre, prospective cohort study
Carrillo F, Ojeda S, Sanchez N, Plazaola M, Collado D, Miranda T, Saborio S, Mercado B, Monterrey J, Arguello S, Campredon L, Chu Z, Carlson C, Gordon A, Balmaseda A, Kuan G, Harris E. Comparison of dengue, chikungunya, and Zika among children in Nicaragua across 18 years: a single-centre, prospective cohort study. The Lancet Child & Adolescent Health 2025, 9: 622-633. PMID: 40774783, PMCID: PMC12325154, DOI: 10.1016/s2352-4642(25)00168-3.Peer-Reviewed Original ResearchConceptsPediatric Dengue Cohort StudyAbsence of feverPresence of arthralgiaClinical featuresProspective cohort studyDays of illnessPresence of basophiliaCohort studyDifferential diagnosisUS National InstitutesDengue disease severityFeatures of dengueDengue virus infectionUS National Institutes of HealthConjunctival injectionGeneralised rashAbdominal painZika casesMedian agePaediatric cohortSingle-centrePaediatric populationPapular rashNational Institutes of HealthVirus infectionUnraveling the role of viral interference in disrupting biennial RSV epidemics in northern Stockholm
Li K, Hamrin J, Nilsson A, Weinberger D, Pitzer V. Unraveling the role of viral interference in disrupting biennial RSV epidemics in northern Stockholm. Nature Communications 2025, 16: 8137. PMID: 40885786, PMCID: PMC12398580, DOI: 10.1038/s41467-025-63654-1.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusRespiratory syncytial virus activityViral interferenceH1N1 pandemic influenza virusPandemic H1N1 virusPandemic influenza virusNorthern StockholmBiennial patternH1N1 virusInfluenza virusIn vivo studiesRespiratory virusesSyncytial virusInfluenza pandemicRSV epidemicsBirth rateInfluenzaPublic health interventionsWinter outbreaksVirusAdmission dataH1N1InfantsOlder adultsHealth interventionsRural Community‐Based Interventions to Improve the Mental Health and Wellbeing of Children and Young People: A Rapid Scoping Review of the Quantitative and Qualitative Evidence
McDougal E, Sheikh A, de Lima E, Lereya S, Edbrooke‐Childs J, Deighton J, Hobbs T, Fonagy P, Thompson A. Rural Community‐Based Interventions to Improve the Mental Health and Wellbeing of Children and Young People: A Rapid Scoping Review of the Quantitative and Qualitative Evidence. Journal Of Community Psychology 2025, 53: e70037. PMID: 40884842, PMCID: PMC12398394, DOI: 10.1002/jcop.70037.Peer-Reviewed Original ResearchConceptsCommunity-based interventionsMental Health and WellbeingMental healthImprovement of mental healthScoping review methodologyYouth mental healthWellbeing of childrenIntervention implementationYoung peopleScoping ReviewUnique interventionsIntervention outcomesReview methodologySocial connectednessQualitative evidenceInterventionText screeningHealthExclusion criteriaWellbeingSelf-esteemCommunity relationshipsPositive impactPeopleCopingA Comparison of Novel Serum Markers of Liver Health in Adolescents With Metabolic Dysfunction‐Associated Steatotic Liver Disease
Bade N, Hellman D, Matye D, Jiang S, Tryggestad J, Yu Z, Short K, Palle S. A Comparison of Novel Serum Markers of Liver Health in Adolescents With Metabolic Dysfunction‐Associated Steatotic Liver Disease. Journal Of Cellular And Molecular Medicine 2025, 29: e70817. PMID: 40874510, PMCID: PMC12392135, DOI: 10.1111/jcmm.70817.Peer-Reviewed Original ResearchConceptsMiR-192MiR-122Markers of liver healthCK-18 fragmentsCK-18N-terminal propeptideNormal weightLiver diseaseN-terminal propeptide of type III procollagenSteatotic liver diseaseMiRNA candidatesPropeptide of type III procollagenNon-invasive biomarkersLiver fibrosis stageMiRNAsArea under the receiver operating curveType III procollagenReceiver operating curveLiver histopathological featuresSerum markersFibrosis stageHistopathological featuresLiver healthYKL-40Cytokeratin 18Global Assessment of Relational Functioning: A Dynamic Family Measure Predicting Outcome in Children With Diabetes
Côté‐Olijnyk M, Fonagy P, Zeng Y, Greenwood C, Schiffrin A, Qureshi M, Atsaidis Z, Greenfield B. Global Assessment of Relational Functioning: A Dynamic Family Measure Predicting Outcome in Children With Diabetes. Family Process 2025, 64: e70063. PMID: 40878251, PMCID: PMC12394924, DOI: 10.1111/famp.70063.Peer-Reviewed Original ResearchConceptsGlobal Assessment of Relational FunctioningFamily functioningSelf-report scalesGlobal assessmentHigher family functioningMental health referralsAssociated with better metabolic controlProblem-solving attributesSchool-aged childrenEmotional climateTreatment adherenceHealth referralsTreatment targetFrequency of ER visitsPediatric populationPrevalence of type 1 diabetesBetter metabolic controlDiabetes outcomesHbA1c scoresRelated functionsYouthLongitudinal observational studySerum glycosylated hemoglobinAmerican Diabetes AssociationEpisodes of ketoacidosisGenetic Subtypes of Phelan-McDermid Syndrome Exhibit Similar Rates of Change Despite Differences in Level of Impairment in Developmental Constructs.
Levy T, Farmer C, Srivastava S, Johnson K, Trayvick J, Brune C, Massa A, Silver H, Siper P, Zweifach J, Halpern D, Foss-Feig J, Bernstein J, Berry-Kravis E, Powell C, Sahin M, Soorya L, Thurm A, Buxbaum J, Kolevzon A. Genetic Subtypes of Phelan-McDermid Syndrome Exhibit Similar Rates of Change Despite Differences in Level of Impairment in Developmental Constructs. American Journal On Intellectual And Developmental Disabilities 2025, 130: 395-413. PMID: 40858310, DOI: 10.1352/1944-7558.130.5.395.Peer-Reviewed Original ResearchConceptsPhelan-McDermid syndromeIntellectual disabilityBehavioral domainsDegree of intellectual disabilityBehavioral featuresLevel of impairmentDegree of impairmentIntellectual functioningDevelopmental constructsSequence variantsBehavioral abnormalitiesExpressive languageWithin-subjectAdaptive behaviorBetween-subjectsDevelopmental domainsSimilarity ratingsMedical featuresConsistent with previous resultsLongitudinal dataImpairmentGenetic subtypesGenetic variationGenetic groupsDevelopmental delayPhenotypic variation in neural sensory processing by deletion size, age, and sex in Phelan-McDermid syndrome
Smith M, Berry-Kravis E, Thaliath A, Isenstein E, Durkin A, Foss-Feig J, Siper P, Nelson C, Baczewski L, Levin A, Powell C, Pulver S, Mosconi M, Kolevzon A, Ethridge L. Phenotypic variation in neural sensory processing by deletion size, age, and sex in Phelan-McDermid syndrome. Journal Of Neurodevelopmental Disorders 2025, 17: 51. PMID: 40855273, PMCID: PMC12376477, DOI: 10.1186/s11689-025-09642-4.Peer-Reviewed Original ResearchConceptsInter-trial coherenceAuditory processing abnormalitiesEvent-related spectral perturbationReactivity to sensory stimuliDeletion sizeAuditory stimuliRepetitive auditory stimuliSensory processingGenetic conditionsEvent-related potentialsComparison of event-related potentialsPhelan-McDermid syndromeBackgroundPhelan-McDermid syndromeNeonatal hypotoniaElectroencephalography studyDysmorphic featuresInhibitory modulationNeurophysiological abnormalitiesMethodsA totalEarly recognitionSHANK3 geneClinical characterizationProcessing abnormalitiesDevelopmental delayImpaired processingPromoting Optimal Development: Screening for Mental Health, Emotional, and Behavioral Problems: Clinical Report.
Weitzman C, Guevara J, Curtin M, Macias M, Kinwa Poon J, Joseph Smith P, Christine Augustyn M, Liu Y, Anopawuia Spinks-Franklin A, Zubler J, Navsaria D, Glusman M, Uzoatu Anyigbo C, Chen V, Gonzales J, Guevara J, Nobuhide Hashikawa A, Marie Loria H, Miller-Fitzwater A, Ramachandran U, Edlagan Shah P, Nasir A, Davis B, Gidwani P, Johnson T, Mathieu I, Sriraman N, Spinks-Franklin A, Barbaresi W, Froehlich T, Nielsen B, Poon J, Yang J, Fogler J, Loe I, Godwin D, Nadler C, Wilkins J, Degnon L. Promoting Optimal Development: Screening for Mental Health, Emotional, and Behavioral Problems: Clinical Report. 2025, 156 PMID: 40850690, DOI: 10.1542/peds.2025-073172.Peer-Reviewed Original ResearchConceptsPediatric primary careHealth supervision visitsPrimary careMental healthSupervision visitsRates of mental healthPreventive Pediatric Health CareMental health competenciesPediatric health careAutism Spectrum Disorder ScreeningAmerican Academy of Pediatrics policy statementAmerican AcademyPromote optimal developmentMEB problemCare of childrenBehavior problemsPostpartum depressionDisorder screeningEmotional problemsHealth competenciesHealth careNeeds of youthClinical reportsPositive screenCareShifting respiratory pathogens: Post-COVID-19 trends in community-acquired infections in underserved communities
Rafei R, Osman M, Barake B, Mallat H, Dabboussi F, Hamze M. Shifting respiratory pathogens: Post-COVID-19 trends in community-acquired infections in underserved communities. PLOS ONE 2025, 20: e0329481. PMID: 40845032, PMCID: PMC12373226, DOI: 10.1371/journal.pone.0329481.Peer-Reviewed Original ResearchConceptsInfluenza ARespiratory infectionsLogistic regression modelsCommunity-acquired acute respiratory infectionsRespiratory pathogensCommunity-acquired infectionsParainfluenza virus infectionEpidemiology of respiratory infectionsRespiratory tract infectionsSARS-CoV-2Multivariate logistic regression modelAcute respiratory infectionsAntimicrobial stewardship strategiesLogistic regression analysisGlobal health burdenTract infectionsHuman rhinovirus/enterovirusMulticenter studyParainfluenza virusNasopharyngeal samplesCo-InfectionVirus infectionPatientsRegression modelsPediatric clinic
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply