2025
High- vs low-dose oxytocin protocols for labor induction: a systematic review and meta-analysis
Grasch J, Costantine M, Cahill A, Subramaniam A, Son M, Raghuraman N, Grobman W, Frey H. High- vs low-dose oxytocin protocols for labor induction: a systematic review and meta-analysis. American Journal Of Obstetrics & Gynecology MFM 2025, 7: 101691. PMID: 40334983, DOI: 10.1016/j.ajogmf.2025.101691.Peer-Reviewed Original ResearchConceptsLow-dose oxytocin protocolsOxytocin protocolInduction of laborLabor inductionCesarean deliveryLow-dose protocolVaginal deliveryNeonatal outcome of inductionFrequency of postpartum hemorrhageRisk of cesarean deliveryLikelihood of cesarean deliveryDuration of labor inductionFrequency of cesarean deliveryHigh-dose oxytocin protocolRelative riskCochrane risk of bias assessment toolSystematic reviewRisk of bias assessment toolOxytocin infusion protocolOperative vaginal deliveryHigh-dose oxytocinConfidence intervalsDuration of laborOutcome of inductionHigh risk of biasGestational weight gain and increased risk of cesarean delivery across body mass index categories
MCELFISH P, AYERS B, HAWLEY N, CALDWELL A, PORTER A, MACECHKO M, WATSON D, CALLAGHAN-KORU J, SELIG J, ANDERSEN J, MANNING N, WHITE L, GOMEZ-POMAR E, BROWN C. Gestational weight gain and increased risk of cesarean delivery across body mass index categories. AJOG Global Reports 2025, 5: 100445. PMID: 40027475, PMCID: PMC11869019, DOI: 10.1016/j.xagr.2025.100445.Peer-Reviewed Original ResearchRisk of cesarean deliveryGestational weight gainRate of gestational weight gainHealthy pre-pregnancy BMIIncreased risk of cesarean deliveryPre-pregnancy BMIExcessive rate of gestational weight gainExcessive gestational weight gainCesarean deliveryBMI categoriesAssociated with increased risk of cesarean deliveryCesarean delivery riskPre-pregnancy BMI categoriesLow-risk birthsAmerican College of Obstetricians and GynecologistsReduce cesarean deliveryIncreased GWGVital records dataIncreased riskObstetricians and GynecologistsStudy design analysisAssociated with increased riskProportion of womenMaternal healthExcess rate
2024
Perinatal outcomes are similar in programmed and modified natural frozen embryo transfer cycles
Farrell A, Yuen M, Dodge L, Sakkas D, Vaughan D, Toth T. Perinatal outcomes are similar in programmed and modified natural frozen embryo transfer cycles. Reproductive BioMedicine Online 2024, 49: 104347. PMID: 39213983, DOI: 10.1016/j.rbmo.2024.104347.Peer-Reviewed Original ResearchFrozen embryo transfer cyclesEmbryo transfer cyclesIschemic placental diseasePreterm deliveryPerinatal outcomesPlacental diseaseTransfer cyclesIncreased risk of cesarean deliveryRisk of ischemic placental diseaseIncreased riskRisk of cesarean deliveryNatural FET cyclesIntrauterine growth restrictionNeonatal clinical outcomesModified natural cycleRetrospective cohort studyMode of deliveryCesarean deliverySGA infantsGestational ageFET cyclesGrowth restrictionClinical outcomesCohort studyPatients
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