2024
Estimating the lives that could be saved by expanded access to weight-loss drugs
Pandey A, Ye Y, Wells C, Singer B, Galvani A. Estimating the lives that could be saved by expanded access to weight-loss drugs. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2412872121. PMID: 39405358, PMCID: PMC11513960, DOI: 10.1073/pnas.2412872121.Peer-Reviewed Original ResearchConceptsGlucagon-like peptide-1Body mass index categoriesObesity prevalence dataGlucagon-like peptide-1 receptor agonistsHazard ratio of mortalityRatio of mortalityPublic health impactWeight loss drugsInsurance coverage issuesGastric inhibitory polypeptideHealthcare accessType 2 diabetesUnited StatesPublic health crisisObesity epidemicReceptor agonistsIndex categoriesHazard ratioPrevalence dataInhibitory polypeptidePeptide-1Health impactsNovel treatmentObesityHealth crisisExternal Validation of an Electronic Phenotyping Algorithm Detecting Attention to High Body Mass Index in Pediatric Primary Care
Barron A, Fenick A, Maciejewski K, Turer C, Sharifi M. External Validation of an Electronic Phenotyping Algorithm Detecting Attention to High Body Mass Index in Pediatric Primary Care. Applied Clinical Informatics 2024, 15: 700-708. PMID: 39197473, PMCID: PMC11387092, DOI: 10.1055/s-0044-1787975.Peer-Reviewed Original ResearchConceptsElectronic health recordsBody mass indexPediatric primary careElevated body mass indexWeight-related comorbiditiesPrimary carePediatric primary care practicesElectronic health record dataBody mass index categoriesMass indexImprove obesity managementPrimary care practicesWell-child visitsHigher Body Mass IndexChart reviewLikelihood of classificationElectronic phenotyping algorithmsFree-text componentsClinician typeCare practicesHealth recordsClinician behaviorLaboratory ordersProgress notesObesity managementImpact of Recipient and Donor Body Mass Index on Survival Outcomes After Intestinal Transplantation: A United Network for Organ Sharing Database Analysis
Ameyaw A, Boateng S, Annor E, Njei B. Impact of Recipient and Donor Body Mass Index on Survival Outcomes After Intestinal Transplantation: A United Network for Organ Sharing Database Analysis. Annals Of Transplantation 2024, 29: e943994-1-e943994-13. PMID: 38978263, PMCID: PMC11299477, DOI: 10.12659/aot.943994.Peer-Reviewed Original ResearchConceptsBody mass indexDonor body mass indexIncreased risk of mortalityIntestinal transplantationRisk of mortalityIT recipientsSurvival outcomesMass indexIncreased riskLong-term patient survivalImpact of body mass indexRecipient body mass indexMultivariate Cox regression analysisKaplan-Meier survival curvesBody mass index categoriesLower body mass indexImprove survival outcomesCox regression analysisRetrospective cohort studyAssociation of recipientPost-transplant mortalityImpact of recipientUnderweight patientsPatient survivalObesity classFor Patients Undergoing an Induction of Labor, Does Increased Body Mass Index Necessitate Higher Doses of Misoprostol? [ID 2683640]
Mason-Otey A, Lundsberg L, Culhane J, Merriam A. For Patients Undergoing an Induction of Labor, Does Increased Body Mass Index Necessitate Higher Doses of Misoprostol? [ID 2683640]. Obstetrics And Gynecology 2024, 143: 46s-46s. DOI: 10.1097/01.aog.0001013576.14925.24.Peer-Reviewed Original ResearchInduction of laborBody mass indexBody mass index categoriesDose of misoprostolMisoprostol doseClass IIIMass indexProlonged induction of laborClass IIAssociated with increased BMIClass IIncreased BMIPre-gestational diabetesClass II obesityClass I obesityRetrospective cohort analysisMisoprostol administrationObese patientsII obesityMisoprostolInvestigate safetyHigh dosesPrimary outcomeCohort analysisPatientsOrganochlorine pesticides and risk of papillary thyroid cancer in U.S. military personnel: a nested case-control study
Rusiecki J, McAdam J, Denic-Roberts H, Sjodin A, Davis M, Jones R, Hoang T, Ward M, Ma S, Zhang Y. Organochlorine pesticides and risk of papillary thyroid cancer in U.S. military personnel: a nested case-control study. Environmental Health 2024, 23: 28. PMID: 38504322, PMCID: PMC10949709, DOI: 10.1186/s12940-024-01068-0.Peer-Reviewed Original ResearchConceptsPapillary thyroid cancer riskNested Case-Control StudyPapillary thyroid cancerCase-control studyOdds ratioBody mass index categoriesOrganochlorine pesticidesConfidence intervalsFindings of increased riskRisk of papillary thyroid cancerConditional logistic regressionPre-diagnostic serum samplesIndividually-matched controlsThyroid cancerFollicular variant papillary thyroid cancerSerum concentrationsVariant papillary thyroid cancerEffect modificationU.S. military personnelBirth cohortPapillary thyroid cancer casesBirth yearIndex categoriesDecreased riskEffects of organochlorine pesticidesHigh Body Mass Index and Response to Anti-Tumor Necrosis Factor Therapy in Pediatric Crohn’s Disease
Ebach D, Jester T, Galanko J, Firestine A, Ammoury R, Cabrera J, Bass J, Minar P, Olano K, Margolis P, Sandberg K, Linnville T, Kaplan J, Pitch L, Steiner S, Bass D, Moses J, Adler J, Gulati A, Wali P, Pashankar D, Ivanova A, Herfarth H, Wohl D, Benkov K, Strople J, Sullivan J, Tung J, Molle-Rios Z, Saeed S, Bousvaros A, Kappelman M. High Body Mass Index and Response to Anti-Tumor Necrosis Factor Therapy in Pediatric Crohn’s Disease. The American Journal Of Gastroenterology 2024, 119: 1110-1116. PMID: 38445644, PMCID: PMC11150092, DOI: 10.14309/ajg.0000000000002741.Peer-Reviewed Original ResearchHigher Body Mass IndexNormal body mass indexPediatric Crohn's diseaseBody mass indexAnti-TNF levelsInfliximab initiationTrough levelsTreatment failureObese patientsMass indexTime-to-treatment failureCrohn's diseaseResponse to anti-TNF therapyAssociated with treatment failureMonotherapy to combination therapyBody mass index groupsBody mass index categoriesPrescribed anti-TNFProactive drug monitoringAdalimumab-treated patientsDrug trough levelsAnti-TNF treatmentAnti-TNF therapyInfliximab trough levelsWeight-based dosingTHE IMPACT OF OBESITY ON THE PREVALENCE AND SEVERITY OF PERIANAL COMPLICATIONS OF CROHN'S DISEASE
Youn J, Hsia K, Khadilkar S, Zeina T, Rai P, Rastogi A, Adavelly P, Hussani S, Yanes J, Kotlier J, Spence S, Levy A, Friedman S. THE IMPACT OF OBESITY ON THE PREVALENCE AND SEVERITY OF PERIANAL COMPLICATIONS OF CROHN'S DISEASE. Inflammatory Bowel Diseases 2024, 30: s28-s28. DOI: 10.1093/ibd/izae020.064.Peer-Reviewed Original ResearchPrevalence of perianal diseaseSeverity of perianal diseaseBody mass indexInflammatory bowel diseasePerianal surgeryPerianal diseasePerianal fistula surgeryImpact of obesityFecal diversionPerianal fistulasCrohn's diseaseFistula surgeryMedian timeFamily historyHistory of perianal fistulaBody mass index categoriesFamily history of inflammatory bowel diseaseHistory of inflammatory bowel diseaseMaximum body mass indexIncreasing BMI categoryAssociation of obesityNon-obese patientsPerianal fistulizing diseaseCochran-Armitage trend testTertiary care centerSex-specific associations between habitual snoring and cancer prevalence: insights from a US Cohort Study
Ding Q, Herrin J, Kryger M. Sex-specific associations between habitual snoring and cancer prevalence: insights from a US Cohort Study. SLEEP Advances 2024, 5: zpae051. PMID: 39156215, PMCID: PMC11329803, DOI: 10.1093/sleepadvances/zpae051.Peer-Reviewed Original ResearchNational Health and Nutrition Examination SurveySex-specific associationsBody mass indexCancer prevalenceInverse probability of treatment weightingSleep durationOdds of breast cancerHealth and Nutrition Examination SurveyHabitual snoringBody mass index categoriesU.S. cohort studyNutrition Examination SurveyPrevalence of cancerExamination SurveyCancer typesProbability of treatment weightingHigher oddsCancer casesCancer preventionNon-habitual snorersCohort studyMass indexScreening strategiesHabitual snorersLongitudinal research
2023
Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery
Grasch J, Venkatesh K, Grobman W, Silver R, Saade G, Mercer B, Yee L, Scifres C, Parry S, Simhan H, Reddy U, Frey H. Association of maternal body mass index with success and outcomes of attempted operative vaginal delivery. American Journal Of Obstetrics & Gynecology MFM 2023, 5: 101081. PMID: 37422004, DOI: 10.1016/j.ajogmf.2023.101081.Peer-Reviewed Original ResearchConceptsMaternal body mass indexBody mass indexOperative vaginal deliveryVaginal delivery attemptComposite maternal morbidityComposite neonatal morbidityVaginal deliveryMass indexNeonatal morbidityCesarean deliveryMaternal morbidityAdverse outcomesSecond-stage cesarean deliveryBody mass index groupsBody mass index categoriesNulliparous Pregnancy Outcomes StudyNonanomalous singleton pregnanciesNeonatal adverse outcomesMultivariable logistic regressionPregnancy Outcomes StudyNulliparous individualsDose-dependent mannerSecondary outcomesSingleton pregnanciesPrimary outcomeTirzepatide reduces body weight across body mass index (BMI) categories: A SURMOUNT-1 pre-specified analysis
Aronne L, Jastreboff A, Le Roux C, Malik R, Ahmad N, Liu B, Bunck M, Zhang S, Stefanski A, Lautenbach A. Tirzepatide reduces body weight across body mass index (BMI) categories: A SURMOUNT-1 pre-specified analysis. Diabetologie Und Stoffwechsel 2023, 18: s42-s43. DOI: 10.1055/s-0043-1767938.Peer-Reviewed Original Research
2022
Association between Obesity and Length of COVID-19 Hospitalization: Unexpected Insights from the American Heart Association National COVID-19 Registry
Collins W, Chang A, Weng Y, Dahlen A, O'Brien C, Hom J, Ahuja N, Rodriguez F, Rohatgi N. Association between Obesity and Length of COVID-19 Hospitalization: Unexpected Insights from the American Heart Association National COVID-19 Registry. Journal Of Obesity & Metabolic Syndrome 2022, 31: 277-281. PMID: 36058896, PMCID: PMC9579478, DOI: 10.7570/jomes22042.Peer-Reviewed Original ResearchBody mass indexLength of stayClass II obese patientsPatients admitted to intensive careBMI subjectsNational COVID-19 registryBody mass index categoriesII obese patientsPoor clinical outcomesAdult COVID-19 patientsHalf-day reductionCritically ill patientsFunction of body mass indexCOVID-19 registryCalculated length of stayCOVID-19 patientsObese patientsLaboratory findingsClinical outcomesRespiratory statusMass indexDose-dependentlyMedical historyIll patientsIntensive careSex-Differential Associations Between Body Mass Index and the Incidence of Dementia
Jacob L, Smith L, Koyanagi A, Konrad M, Haro J, Shin J, Kostev K. Sex-Differential Associations Between Body Mass Index and the Incidence of Dementia. Journal Of Alzheimer’s Disease 2022, 88: 631-639. PMID: 35662122, DOI: 10.3233/jad-220147.Peer-Reviewed Original ResearchConceptsIncidence of dementiaBody mass indexAssociated with dementiaGeneral practiceBody mass index categoriesMass indexIncreased BMIRetrospective cohort studyNormal weightSex-differential associationCohort studyDementiaLate lifeOlder womenStudy variablesKaplan-Meier curvesCox regression analysisWomenRegression analysisObesityAssociationMenSexSex differencesIncidence
2020
Mediation of the association between maternal pre-pregnancy overweight/obesity and childhood overweight/obesity by birth anthropometry
Stevens DR, Neelon B, Roberts JR, Taylor SN, Newman RB, Vena JE, Hunt KJ. Mediation of the association between maternal pre-pregnancy overweight/obesity and childhood overweight/obesity by birth anthropometry. Journal Of Developmental Origins Of Health And Disease 2020, 12: 71-78. PMID: 32077839, PMCID: PMC7438242, DOI: 10.1017/s2040174420000033.Peer-Reviewed Original ResearchConceptsOffspring overweight/obesityOverweight/obesityMaternal pre-pregnancy overweight/obesityPre-pregnancy overweight/obesityChildhood overweight/obesityBirth anthropometryOffspring anthropometryUtero exposureMaternal body mass index (BMI) categoryMaternal overweight/obesityBody mass index categoriesNatural direct effectNatural indirect effectGestational diabetesHypertensive disordersRetrospective cohortObesityIndex categoriesMother-child dyadsDevelopmental programmingBiologic pathwaysHospital systemAnthropometryAssociationBirthDifferences in Frequency of Visits to Pediatric Primary Care Practices and Emergency Departments by Body Mass Index
Kovalerchik O, Powers E, Holland ML, Sharifi M, Langhan ML. Differences in Frequency of Visits to Pediatric Primary Care Practices and Emergency Departments by Body Mass Index. Academic Pediatrics 2020, 20: 532-539. PMID: 31904438, DOI: 10.1016/j.acap.2019.12.011.Peer-Reviewed Original ResearchConceptsPrimary care visitsCare visitsBMI percentile categoryED visitsNormal BMISevere obesityBMI categoriesIndex primary care visitPediatric primary care practicesBody mass index categoriesEmergency department visitsRisk of hospitalizationPediatric weight managementPrevalence of overweightBody mass indexHealth care utilizationNormal BMI rangeCare-seeking patternsPrimary care practicesChildren’s BMI categoryHealth care settingsRace/ethnicityElectronic health recordsImpact of stigmaIndex visit
2018
Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study
Chekroud SR, Gueorguieva R, Zheutlin AB, Paulus M, Krumholz HM, Krystal JH, Chekroud AM. Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study. The Lancet Psychiatry 2018, 5: 739-746. PMID: 30099000, DOI: 10.1016/s2215-0366(18)30227-x.Peer-Reviewed Original ResearchConceptsMental health burdenCross-sectional studyHealth burdenExercise typeMental healthPhysical exerciseBehavioral Risk Factor Surveillance System surveyPast monthBody mass index categoriesEffective clinical targetsPrevention's Behavioral Risk Factor Surveillance System (BRFSS) surveysSelf-reported mental healthFrequency of exerciseSelf-reported physical healthFunction of exerciseMultiple sensitivity analysesPoor mental healthTerms of ageCause mortalityPrevious diagnosisPotential confoundersInterventional studyCardiovascular diseaseReduced riskIndex categories
2015
Obesity Modifies the Effect of Fitness on Heart Rate Indices during Exercise Stress Testing in Asymptomatic Individuals
Aneni EC, Oni ET, Osondu CU, Martin SS, Blaha MJ, Veledar E, Agatston AS, Feldman T, Carvalho JA, Conceição RD, Santos RD, Nasir K. Obesity Modifies the Effect of Fitness on Heart Rate Indices during Exercise Stress Testing in Asymptomatic Individuals. Cardiology 2015, 132: 242-248. PMID: 26329389, DOI: 10.1159/000435907.Peer-Reviewed Original ResearchConceptsHeart rateHR recoveryDifferent body mass index (BMI) categoriesBody mass index categoriesExercise stress testExercise stress testingExercise heart ratePeak heart rateHeart rate indexCross-sectional analysisEffects of fitnessObesity modifiesAsymptomatic cohortPeak exerciseBMI categoriesObese subjectsAsymptomatic individualsMetabolic equivalentsIndex categoriesMultivariate analysisAerobic fitnessBrazilian subjectsWeight lossStatistical significanceStress testingImpact of obesity in patients with metastatic urothelial carcinoma.
Leiter A, Doucette J, Krege S, Lin C, Hahn N, Ecke T, Sonpavde G, Bamias A, Oh W, Galsky M. Impact of obesity in patients with metastatic urothelial carcinoma. Journal Of Clinical Oncology 2015, 33: 346-346. DOI: 10.1200/jco.2015.33.7_suppl.346.Peer-Reviewed Original ResearchBody surface area categoriesBody surface areaBody mass indexIncidence of embolic eventsMetastatic urothelial cancerCisplatin-based therapyAverage body surface areaImpact of obesityUrothelial cancerNo significant differenceSurvival outcomesEmbolic eventsAdverse eventsSignificant differenceCisplatin-based combination therapyResponse rateAssociated with worse outcomesBody mass index categoriesHigher body surface areaMetastatic urothelial carcinomaNon-obese patientsOutcomes of patientsHigher BMI categoriesMetastatic diseaseChemotherapy regimens
2010
Multiparity is Associated With High Motivation to Change Diet Among Overweight and Obese Postpartum Women
Bastian LA, Pathiraja VC, Krause K, Brouwer R, Swamy GK, Lovelady CA, Østbye T. Multiparity is Associated With High Motivation to Change Diet Among Overweight and Obese Postpartum Women. Women's Health Issues 2010, 20: 133-138. PMID: 20149971, PMCID: PMC2849268, DOI: 10.1016/j.whi.2009.11.005.Peer-Reviewed Original ResearchMeSH KeywordsAdultBody Mass IndexDietDietary CarbohydratesDietary FatsDietary ProteinsFemaleFollow-Up StudiesHealth BehaviorHumansInfant, NewbornMaternal Nutritional Physiological PhenomenaMothersMotivationObesityPostpartum PeriodPregnancyRandomized Controlled Trials as TopicRegression AnalysisSurveys and QuestionnairesUnited StatesWomen's HealthYoung AdultConceptsObese postpartum womenPostpartum womenPrimigravid womenFirst pregnancyEffect of parityBody mass index categoriesActive Mothers PostpartumCohort of overweightPostpartum weight reductionWoman's first pregnancyThird of participantsMothers postpartumPotential confoundersThird pregnancyMultivariable modelIndex categoriesLogistic regressionPregnancyWeight gainWomenMore childrenDietOverweightObesityWeight reduction
2009
Contraceptive use by obese women 1 year postpartum
Chin JR, Swamy GK, Østbye T, Bastian LA. Contraceptive use by obese women 1 year postpartum. Contraception 2009, 80: 463-468. PMID: 19835721, PMCID: PMC2764535, DOI: 10.1016/j.contraception.2009.03.017.Peer-Reviewed Original ResearchConceptsActive Mothers PostpartumEffective contraceptive useObese womenContraceptive useEffective contraceptionMonths postpartumUnintended pregnancyContraceptive methodsBody mass index categoriesPostpartum weight reductionEffective contraceptive methodsCertain contraceptive methodsBMI 30Pregnancy complicationsOverweight womenMothers postpartumYear postpartumPotential confoundersChronic illnessMultivariable modelIndex categoriesSecondary analysisPostpartumLogistic regressionBMI
2006
Number of Children and Risk of Metabolic Syndrome in Women
Cohen A, Pieper CF, Brown AJ, Bastian LA. Number of Children and Risk of Metabolic Syndrome in Women. Journal Of Women's Health 2006, 15: 763-773. PMID: 16910908, DOI: 10.1089/jwh.2006.15.763.Peer-Reviewed Original ResearchConceptsMetabolic syndromeNumber of childrenNational Cholesterol Education Program Expert PanelBody mass index categoriesHistory of breastfeedingHigh blood cholesterolMetabolic syndrome riskBehavioral risk factorsNutrition Examination SurveyThird National HealthDose-response relationshipAssociation of numberRace/ethnicityATP IIINonpregnant womenParous womenExamination SurveyNational HealthRisk factorsBlood cholesterolSyndrome riskHigh prevalenceReproductive factorsAdditional adjustmentEffect of parity
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