2025
Glucagon-Like Peptide-1 Receptor Agonist Eligibility Among US Adolescents and Young Adults
Chetty A, Sharifi M, Nugent J. Glucagon-Like Peptide-1 Receptor Agonist Eligibility Among US Adolescents and Young Adults. JAMA Pediatrics 2025, 179 PMID: 40758363, PMCID: PMC12322816, DOI: 10.1001/jamapediatrics.2025.2308.Peer-Reviewed Original ResearchAssociation between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study
Yoon C, Meadan H, Xia Y, Shic F. Association between joint attention and autism traits in young adults: A gaze-contingent eye-tracking study. Research In Autism 2025, 125: 202622. DOI: 10.1016/j.reia.2025.202622.Peer-Reviewed Original ResearchAssociated with autism traitsAutism traitsJoint attentionEye-tracking taskInteractive eye-trackingTraits in adulthoodEye-tracking methodologyYoung adultsDifficulties associated with autismEye-tracking studyHuman communication partnerEye-tracking researchAttentional demandsAutistic childrenCommunication partnersAutismEye trackingAttention variationDevelopmental significanceAdulthoodTraitsAdultsLinear mixed modelsAttentionAdolescents1186-P: A Short-Term Low Carbohydrate Diet Improves Glycemia in Adolescents and Young Adults with Type 1 Diabetes—Results from a Randomized Crossover Study
NALLY L, LUKASIK J, HERZOG R, MITTENDORFER B, GOSS A, SAVOYE M, ROSE P, MCCOLLUM S, SHABANOVA V, SHERR J. 1186-P: A Short-Term Low Carbohydrate Diet Improves Glycemia in Adolescents and Young Adults with Type 1 Diabetes—Results from a Randomized Crossover Study. Diabetes 2025, 74 DOI: 10.2337/db25-1186-p.Peer-Reviewed Original ResearchLow-carbohydrate dietRandomized Crossover StudyCrossover studyCarbohydrate dietPotential treatment optionStandard carbohydrate dietLower glycemic variabilityRandomized Controlled TrialsDietary recallsMetabolic kitchenTreatment optionsIncreasing hypoglycemiaImprove glycemiaGlycemic variabilityControlled TrialsT1DGlycemic benefitsWeekend daysHypoglycemiaIncreasing timeYoung adultsDietYouthGlycemiaHyperglycemiaThe Effect of “Ice” Components in Sweet-Flavored Nicotine-Containing E-Liquids Among Young Adult E-Cigarette Users
Li W, Davis D, Wu R, Gueorguieva R, Green B, Krishnan-Sarin S. The Effect of “Ice” Components in Sweet-Flavored Nicotine-Containing E-Liquids Among Young Adult E-Cigarette Users. Experimental And Clinical Psychopharmacology 2025 PMID: 40489161, DOI: 10.1037/pha0000786.Peer-Reviewed Original ResearchWatermelon flavorRewarding effectsGeneral Labeled Magnitude ScaleE-cigarette usersEffects of flavorYoung adult e-cigarette usersFlavor likingHedonic scaleAdult e-cigarette usersLabeled Hedonic ScaleFlavorWatermelonDrug Effects QuestionnaireFlavor conditioningE-liquidsYoung adultsPast-month e-cigarette usersPropylene glycol/vegetable glycerinSensory effectsE-cigarettesFixed effectsNicotine e-liquidE-cigarette useLikingLaboratory sessionsJoint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States.
Chu L, Wang R, Gross C, Wei J, Lu Y, Krumholz H, Ma X, Chen K. Joint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States. Circulation 2025 PMID: 40458867, DOI: 10.1161/circulationaha.124.073614.Peer-Reviewed Original ResearchIncident acute myocardial infarctionAcute myocardial infarctionIncreased oddsRisk of acute myocardial infarctionHigher risk of acute myocardial infarctionProbability of acute myocardial infarctionOccurrence of acute myocardial infarctionRandom-effects meta-analysisCase-crossover studyMultivariate random-effects meta-analysisExposure to ozoneRegion-specific estimatesMyocardial infarctionStatistical interaction termsAmbient ozone pollutionPrevention strategiesUnited StatesJoint exposureMeta-analysisAdult ageYoung adultsHigh riskAdultsOddsInteraction termsImpact of age on financial toxicity among breast cancer patients with resectable invasive breast cancer: A systematic review.
Myers S, Morton C, Bain P, Obeng-Gyasi S, Paskett E, McAlearney A, Greenup R, Minami C, Mittendorf E, King T. Impact of age on financial toxicity among breast cancer patients with resectable invasive breast cancer: A systematic review. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e23194.Peer-Reviewed Original ResearchCancer-related costsFinancial toxicitySystematic reviewInvasive breast cancerSocial determinants of healthBreast cancerSymptoms of breast cancerBlood Institute assessment toolIncidence of breast cancerOutcome metricsPatient-reported outcome metricsStage I-III breast cancerDeterminants of healthI-III breast cancerNon-metastatic invasive breast cancerAffordability of careBreast cancer diagnosisYounger ageYoung adultsInstitute assessment toolEnglish-language articlesHealth disparitiesSocial determinantsTreatment-related expensesWeb of ScienceCancer care for adolescents and young adults under the age of 50 in Saudi Arabia: policy review, research gaps, and future directions
Alessy S, Alghamdi M, Al-Bawardy B, Alghamdi S, Al-Hamoudi W, Alomaim W, Abaalkhail F, Alqarni A, Alsharm A, Alqurashi Y, Bokhary M, Alqahtani S. Cancer care for adolescents and young adults under the age of 50 in Saudi Arabia: policy review, research gaps, and future directions. EClinicalMedicine 2025, 103188. DOI: 10.1016/j.eclinm.2025.103188.Peer-Reviewed Original ResearchCancer incidence ratesPatient-centred careIncreasing cancer incidence ratesPublic health challengeYoung adultsSurvivorship carePsychological Well-BeingCancer carePsychosocial needsCare providersCancer ratesYears of ageHealthcare institutionsHealth challengesIncidence rateAYACareSaudi ArabiaUnified treatment protocolRisk factorsPolicy developmentPolicy reviewResearch initiativesTargeted researchAdultsPolygenic risks for depression and neural responses to reward and punishment in young adults
Chen Y, Li H, Luo X, Li G, Ide J, Li C. Polygenic risks for depression and neural responses to reward and punishment in young adults. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2025 PMID: 40412620, DOI: 10.1016/j.bpsc.2025.05.008.Peer-Reviewed Original ResearchPolygenic risk scoresPunishment processingNeural responsesAchenbach Adult Self-ReportInfluence of genetic riskCortical activityAdult Self-ReportYoung adultsGenetic riskRisk of depressionGambling TaskAberrant rewardDrinking severityHuman Connectome ProjectDepression severityPublished routinesBrain responsesPolygenic riskDepression scoresSelf-ReportDepressionConnectome ProjectRewardBrain imagingPunishmentDevelopment and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults.
Nanna M, Wojdyla D, Peterson E, Navar A, Williamson J, Colantonio L, Wang S, Jamil Y, Bertoni A, Nahid M, Damluji A, Goyal P, Chaudhry S, Gill T, Alexander K. Development and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults. Journal Of The American Heart Association 2025, 14: e038949. PMID: 40401627, DOI: 10.1161/jaha.124.038949.Peer-Reviewed Original ResearchConceptsRisk of cognitive impairmentAtherosclerotic cardiovascular disease eventsAtherosclerotic cardiovascular diseaseRisk prediction modelCognitive impairmentOlder adultsMeasures of healthIncident cognitive impairmentOlder person's riskPooled Cohort EquationsCardiovascular diseaseRisk of deathCohort EquationsFramingham OffspringOlder personsExternal validationFunctional statusPersonal riskIncidence riskValidation cohortYoung adultsInternal validityFraminghamCohortTreatment decisionsPsychosocial Stressors Explaining the Monosexual–Bisexual Disparity in Mental Health: A Population-Based Study of Sexual-Minority Young Adults
Clark K, Dyar C, Bränström R, Pachankis J. Psychosocial Stressors Explaining the Monosexual–Bisexual Disparity in Mental Health: A Population-Based Study of Sexual-Minority Young Adults. Clinical Psychological Science 2025, 13: 489-505. DOI: 10.1177/21677026241286875.Peer-Reviewed Original ResearchSexual minority young adultsGeneral life stressorsMental health problemsSexual identity centralityGender of sexual partnersMental healthBisexual peopleBisexual respondentsGender conformityLife stressorsLatent class analysisSexual attractionBisexual subgroupsClass analysisPeople's mental healthYoung adulthoodPsychosocial stressorsSexual partnersYoung adultsGenderNonprobability samplingPopulation-based studyHealthRespondentsAnalyzed dataPrevalence of common mental disorders and sleep disorder among adolescents and young adults with HIV: a systematic review and meta-analysis
Tan Y, Ma Z, Cao Q, Gao S, Xiong Y. Prevalence of common mental disorders and sleep disorder among adolescents and young adults with HIV: a systematic review and meta-analysis. BMJ Open 2025, 15: e093320. PMID: 40379341, PMCID: PMC12083388, DOI: 10.1136/bmjopen-2024-093320.Peer-Reviewed Original ResearchConceptsPrevalence of depressionPrevalence of sleep disordersPooled prevalenceSleep disordersRisk of depressionPost-traumatic stress disorderSubgroup analysisHIV-uninfected peersSensitive screening strategyPublication biasPooled prevalence of depressionCertainty of evidenceYoung adultsCase reportEvaluate study qualityPooled prevalence of anxietyFixed-effects modelPrevalence of anxietySources of heterogeneityWeb of ScienceHIVObservational studyPooled estimatesPrevalence of post-traumatic stress disorderRecommendations AssessmentFocusing attention in working and long-term memory through dissociable mechanisms
Gong D, Draschkow D, Nobre A. Focusing attention in working and long-term memory through dissociable mechanisms. Nature Communications 2025, 16: 4126. PMID: 40319062, PMCID: PMC12049562, DOI: 10.1038/s41467-025-59359-0.Peer-Reviewed Original ResearchConceptsLong-term memoryWorking memoryPerceptual tasksLTM representationsSpatial working memoryMemory typesSensory information processingAttentional orientingAttentional prioritizationMemory itemsHealthy young adultsGaze biasAttentional cuesVisual discriminationVisual stimuliItem matchingEye trackingInformation processingBenefit performanceYoung adultsMemoryGaze shiftsNon-spatialTaskItemsWearable Intervention for Alcohol Use Risk and Sleep in Young Adults
Fucito L, Ash G, Wu R, Pittman B, Barnett N, Li C, Redeker N, O’Malley S, DeMartini K. Wearable Intervention for Alcohol Use Risk and Sleep in Young Adults. JAMA Network Open 2025, 8: e2513167. PMID: 40445615, PMCID: PMC12125640, DOI: 10.1001/jamanetworkopen.2025.13167.Peer-Reviewed Original ResearchConceptsSleep-related impairmentWorld Health OrganizationSecondary outcomesPrimary outcomeSelf-MonitoringSleep-related impairment scoresSleep disturbanceYoung adultsSleep healthWearable feedbackRandomized clinical trialsExploratory outcomesPrevalence of alcohol use disordersAt-risk drinkingIntention-to-treat approachTechnology-based interventionsRisk level reductionMeasures of sleep healthOutcomes of sleep disturbancesSmartphone self-monitoringControl A groupWeek 4Heavy drinking occasionsIntervention groupAlcohol use riskParenting in Childhood Predicts Personality in Early Adulthood: A Longitudinal Twin-Differences Study
Wertz J, Moffitt T, Blangis F, Ambler A, Arseneault L, Danese A, Fisher H, Caspi A. Parenting in Childhood Predicts Personality in Early Adulthood: A Longitudinal Twin-Differences Study. American Psychologist 2025 PMID: 40244963, DOI: 10.1037/amp0001508.Peer-Reviewed Original ResearchPersonality traitsEnvironmental Risk Longitudinal Twin StudyImportant life outcomesLongitudinal Twin StudyTwin differences designIncreasing positive parentingImpact of parentingChildhood maltreatmentBritish twinsChild effectsPositive parentingInfluence personalityMother's affectionTwin studiesEarly adolescencePredicting personalityEarly adulthoodAffectionate parentingLife outcomesYoung adultsChildhood yearsPersonsChildhoodAged 5Family supportDevelopment of a Suicide Prevention Intervention for Sexual and Gender Minority Youth and Young Adults: Rationale, Design, and Evidence of Feasibility and Acceptability
van der Star A, Randall A, Salgin L, Brady J, Albright C, Mitzner J, Alexander J, Williams K, Weersing V, Calzo J, Rojas S, Ramers C, Wells K, Blashill A. Development of a Suicide Prevention Intervention for Sexual and Gender Minority Youth and Young Adults: Rationale, Design, and Evidence of Feasibility and Acceptability. Suicide And Life-Threatening Behavior 2025, 55: e70014. PMID: 40179218, PMCID: PMC11968012, DOI: 10.1111/sltb.70014.Peer-Reviewed Original ResearchConceptsSafety Planning InterventionSGM youthPatient navigationStudy proceduresAcceptability of study proceduresGender minority youthYoung adultsSuicide prevention interventionsEvidence of feasibilityAt-risk populationsGender minoritiesMinority youthModular interventionRepeat-suicide attemptersPreventive interventionsPrevent SuicidePlanning interventionsAt-riskYouthCase seriesSatisfaction rateIdentical careInterventionTriangulated dataSGMThe role of childhood social fragmentation and perceived discrimination on maladaptive core schemas later in life among young adults at clinical high risk for psychosis and healthy comparisons
Diomino A, Yuan Q, Cadenhead K, Addington J, Bearden C, Cannon T, Keshavan M, Mathalon D, Perkins D, Stone W, Walker E, Woods S, Ku B. The role of childhood social fragmentation and perceived discrimination on maladaptive core schemas later in life among young adults at clinical high risk for psychosis and healthy comparisons. Schizophrenia Research 2025, 279: 71-78. PMID: 40174486, PMCID: PMC12035737, DOI: 10.1016/j.schres.2025.03.023.Peer-Reviewed Original ResearchConceptsClinical high riskCore schemasHealthy comparisonNeighbourhood social fragmentationNorth American Prodrome Longitudinal Study 2Perceived DiscriminationSocial fragmentationIn adulthoodNegative-self schemaPoor social functioningCross-sectional studyLongitudinal Study 2High riskU.S. Census dataNegative-selfStudy 2Design interventionsSchema formationSocial functioningPsychosisBaseline dataYoung adultsCensus dataAdulthoodChildhoodEpistemic mistrust mediates the association between childhood maltreatment and impairments in mentalizing in a sample of university students
Schwarzer N, Behringer N, Dees P, Gingelmaier S, Henter M, Kirsch H, Kreuzer T, Langnickel R, Link P, Müller S, Turner A, Fonagy P, Nolte T. Epistemic mistrust mediates the association between childhood maltreatment and impairments in mentalizing in a sample of university students. Child Abuse & Neglect 2025, 163: 107436. PMID: 40168917, DOI: 10.1016/j.chiabu.2025.107436.Peer-Reviewed Original ResearchConceptsExperiences of childhood maltreatmentAttachment insecurityEpistemic mistrustChildhood maltreatmentMental abilitySample of university studentsChildhood maltreatment experiencesImprove mentalizing abilitiesYoung adultsMental health developmentCross-sectional study designCross-sectional naturePsychotherapeutic interventionsMaltreatment experiencesStructural equation modelingMental deficitsPsychosocial functioningPsychosocial interventionsSelf-ReportMaltreatmentMentalMental impairmentAssociated with limitationsUniversity studentsHealth developmentSubstance Misuse, Executive Function, and Young Adult Intimate Partner Violence: Direct and Indirect Pathways.
Martin E, Ramos K, Modanesi E, Mayes L, Stover C. Substance Misuse, Executive Function, and Young Adult Intimate Partner Violence: Direct and Indirect Pathways. Journal Of Interpersonal Violence 2025, 8862605251326641. PMID: 40123291, DOI: 10.1177/08862605251326641.Peer-Reviewed Original ResearchIntimate partner violence riskIntimate partner violenceEarly adolescent substance usePrenatal drug exposureAdolescent substance useExecutive functionSubstance useMaternal educationAdult intimate partner violencePredicting intimate partner violencePrevent intimate partner violenceHigh-risk subjectsYoung adult relationshipsContribution of childhood maltreatmentDevelopmental trajectories of individualsAdolescents' executive functionLow maternal educationWell-being consequencesEnhance executive functionLongitudinal birth cohortYoung adultsDrug exposureIPV riskPartner violenceSex-specific effectsSexual orientation differences in mental health service use and unmet mental health care needs: a cross-sectional population-based study of young adults
Roxo L, Pachankis J, Bränström R. Sexual orientation differences in mental health service use and unmet mental health care needs: a cross-sectional population-based study of young adults. Social Psychiatry And Psychiatric Epidemiology 2025, 1-10. PMID: 40067368, DOI: 10.1007/s00127-025-02866-8.Peer-Reviewed Original ResearchMental health service useHealth service useMental health servicesService useHealth servicesSexual orientation differencesSociodemographic factorsSexual minority individualsUnmet mental health care needsUnmet mental health servicePopulation-based study of young adultsCross-sectional population-based studyMental health service needsUnmet needsMental health care needsMinority individualsUnmet mental health carePerceived needHealth service needsMental health careHealth care needsSexual orientationYoung adultsCulturally sensitive servicesStudy of young adultsPerson-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood
Sisk L, Keding T, Ruiz S, Odriozola P, Kribakaran S, Cohodes E, McCauley S, Zacharek S, Hodges H, Haberman J, Pierre J, Caballero C, Baskin-Sommers A, Gee D. Person-centered analyses reveal that developmental adversity at moderate levels and neural threat/safety discrimination are associated with lower anxiety in early adulthood. Communications Psychology 2025, 3: 31. PMID: 40044923, PMCID: PMC11882445, DOI: 10.1038/s44271-025-00193-x.Peer-Reviewed Original ResearchNeural activityAdverse exposuresMiddle childhoodLower anxietyAssociated with lower anxietyWithin-person combinationsPerson-centered analysesPerson-centered approachHigher neural activityPatterns of adversity exposureCorticolimbic circuitryModerate adversityParsing heterogeneityAnxiety symptomsSafety learningDevelopmental adversityLatent profilesLifetime adversityNeurobiological functionsFuture anxietyAnxietyEarly adulthoodAssociated with processesAdversityYoung adults
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