2025
Poor surgical outcomes following Paenibacillus infant infectious hydrocephalus.
Ericson J, Natukwatsa D, Ssenyonga P, Onen J, Mugamba J, Mulondo R, Morton S, Movassagh M, Templeton K, Hehnly C, Mbabazi-Kabachelor E, Kulkarni A, Warf B, Broach J, Paulson J, Schiff S. Poor surgical outcomes following Paenibacillus infant infectious hydrocephalus. Journal Of Neurosurgery Pediatrics 2025, 1-12. PMID: 40378477, PMCID: PMC12211056, DOI: 10.3171/2025.1.peds24254.Peer-Reviewed Original ResearchPostinfectious hydrocephalusPP patientsPN patientsEndoscopic diversionHydrocephalus surgeryPositive CSF polymerase chain reactionPrimary outcomeMedian follow-up periodCSF polymerase chain reactionFailure-free survivalPoor surgical outcomesPrimary event rateFollow-up periodOverall survivalCSF diversionHydrocephalic infantsSurgical outcomesNeurosurgical evaluationPolymerase chain reactionCompare outcomesSecondary outcomesPatientsEvent ratesInfantsChain reactionRisk Factors in Patients Who Had Prior Renal or Liver Transplant Undergoing Primary Total Hip Arthroplasty
Gill V, Boddu S, Mansour E, Abu Jawdeh B, Khan M, McGary A, Clarke H, Spangehl M, Abdel M, Ledford C, Bingham J. Risk Factors in Patients Who Had Prior Renal or Liver Transplant Undergoing Primary Total Hip Arthroplasty. Journal Of Clinical Medicine 2025, 14: 3486. PMID: 40429481, PMCID: PMC12111864, DOI: 10.3390/jcm14103486.Peer-Reviewed Original ResearchAmerican Society of Anesthesiologists classSolid organ transplantationAmerican Society of Anesthesiologists class 4Associated with high mortalitySurgical complicationsAcute medical complicationsRenal transplantationLiver transplantationMedical complicationsOlder agePeri-operative risk profileOrgan transplantationHistory of solid organ transplantationMedian follow-up periodRisk factorsLikelihood of surgical complicationsTotal hip arthroplastyKaplan-Meier survival analysisRate of reoperationHigher mortalityAssociated with higher riskProportion of patientsFollow-up periodEstimate median survivalLow surgical complicationsP-1158. Surgical Outcomes Following Paenibacillus Infant Infectious Hydrocephalus
Ericson J, Natukwatsa D, Ssenyonga P, Onen J, Mugamba J, Mulondo R, Morton S, Templeton K, Hehnly C, Mbabazi-Kabachelor E, Kulkarni A, Warf B, Broach J, Paulson J, Schiff S. P-1158. Surgical Outcomes Following Paenibacillus Infant Infectious Hydrocephalus. Open Forum Infectious Diseases 2025, 12: ofae631.1344. PMCID: PMC11776767, DOI: 10.1093/ofid/ofae631.1344.Peer-Reviewed Original ResearchPostinfectious hydrocephalusPP patientsPN patientsCerebrospinal fluidEndoscopic diversionHydrocephalus surgeryPositive CSF polymerase chain reactionPrimary outcomeMedian follow-up periodCSF polymerase chain reactionFailure-free survivalPrimary event rateFollow-up periodOverall survivalSurgical outcomesHydrocephalic infantsSurgical managementSurgery typePreoperative testingNeurosurgical evaluationPolymerase chain reactionCompare outcomesSecondary outcomesPatientsSurgery
2024
A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers
Dhingra L, Sangha V, Aminorroaya A, Bryde R, Gaballa A, Ali A, Mehra N, Krumholz H, Sen S, Kramer C, Martinez M, Desai M, Oikonomou E, Khera R. A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers. The American Journal Of Cardiology 2024, 237: 35-40. PMID: 39581517, PMCID: PMC11761372, DOI: 10.1016/j.amjcard.2024.11.028.Peer-Reviewed Original ResearchCleveland Clinic FoundationHypertrophic cardiomyopathyMedian follow-up periodHypertrophic cardiomyopathy therapyMonitoring Treatment ResponseFollow-up periodImpact of therapyAtlantic Health SystemLack of improvementOral alternativePost-SRTMedical therapyTreatment responseMulticenter evaluationInterventricular septumPercutaneous reductionMavacamtenTherapyPatientsClinic FoundationPoint-of-care monitoringECGECG imagesScoresHealth systemBlood Magnesium Level and Risk of Hepatocellular Carcinoma in a Prospective Liver Cirrhosis Cohort.
Zhang X, Zhao L, Dai Q, Hou T, Danford C, Lai M, Zhang X. Blood Magnesium Level and Risk of Hepatocellular Carcinoma in a Prospective Liver Cirrhosis Cohort. Cancer Epidemiology Biomarkers & Prevention 2024, 33: 1368-1374. PMID: 39037332, PMCID: PMC11579948, DOI: 10.1158/1055-9965.epi-24-0327.Peer-Reviewed Original ResearchConceptsRisk of hepatocellular carcinomaBlood magnesium levelsHepatocellular carcinomaLiver cirrhosisMagnesium levelsAssociated with higher HCC riskHigh risk of hepatocellular carcinomaHazard ratioMedian follow-up periodEnd-stage liver disease scoreIdentification of high-risk patientsHigh riskHigher HCC riskHigher magnesium intakeIncident hepatocellular carcinomaHigh-risk patientsLiver Disease scoreFollow-up periodCox proportional hazards modelsBody mass indexConfidence intervalsAlcoholic liver diseaseClassification of Diseases codesProportional hazards modelInternational Classification of Diseases codesLongitudinal Assessment of Left Atrial Remodeling in Patients With Chronic Severe Aortic Regurgitation
Akintoye E, El Dahdah J, Dabbagh M, Patel H, Badwan O, Braghieri L, Chedid El Helou M, Kassab J, Jellis C, Desai M, Rodriguez L, Grimm R, Roselli E, Griffin B, Popovic Z. Longitudinal Assessment of Left Atrial Remodeling in Patients With Chronic Severe Aortic Regurgitation. JACC Cardiovascular Imaging 2024, 17: 1133-1145. PMID: 38878040, DOI: 10.1016/j.jcmg.2024.04.007.Peer-Reviewed Original ResearchLeft atrial volume indexLeft atrial reservoir strainAortic regurgitationLV parametersAssociated with survival benefitMedian follow-up periodChronic severe aortic regurgitationLeft ventricular (LVShort-term follow-upOptimal discriminatory thresholdsSevere aortic regurgitationAtrial volume indexIncremental prognostic valueAtrial reservoir strainLeft atrial remodelingFollow-up periodAssociated with survivalPredicting adverse eventsReservoir strainSerial echocardiographySevere ARSurvival benefitLA remodelingLV remodelingPrognostic valueImmune checkpoint inhibitors in high‐grade upper tract urothelial carcinoma: Paradigm shift emphasizing organ preservation
Khalil M, Fishman A, Komorowski A, Franco I, Grasso M. Immune checkpoint inhibitors in high‐grade upper tract urothelial carcinoma: Paradigm shift emphasizing organ preservation. BJUI Compass 2024, 5: 604-610. PMID: 38751949, PMCID: PMC11090768, DOI: 10.1002/bco2.335.Peer-Reviewed Original ResearchImmune check point inhibitorsHigh-grade upper tract urothelial carcinomaUpper tract urothelial carcinomaMetastasis-free survival ratesGroup 2Group 1Survival rateUrothelial carcinomaSurvival outcomesMedian follow-up periodImpact of clinical characteristicsCheck-point inhibitorsImmune checkpoint inhibitorsEndoscopically treated patientsInitial tumor sizeImprove survival outcomesOverall survival rateKaplan-Meier analysisFollow-up periodImproved survival ratesCheckpoint inhibitorsPoint inhibitorsExtirpative surgeryTumor sizeClinical characteristicsLeadless pacemakers at 5-year follow-up: the Micra transcatheter pacing system post-approval registry
El-Chami M, Garweg C, Clementy N, Al-Samadi F, Iacopino S, Martinez-Sande J, Roberts P, Tondo C, Johansen J, Vinolas-Prat X, Cha Y, Grubman E, Bordachar P, Stromberg K, Fagan D, Piccini J. Leadless pacemakers at 5-year follow-up: the Micra transcatheter pacing system post-approval registry. European Heart Journal 2024, 45: 1241-1251. PMID: 38426911, PMCID: PMC10998730, DOI: 10.1093/eurheartj/ehae101.Peer-Reviewed Original ResearchPost-Approval RegistryLong-term outcomesMonths post-implantMicra leadless pacemakerFollow-upImplantation attemptRevision rateLeadless pacemakerProcedure-related major complicationsMedian follow-up periodPost-implantDuration of follow-upMid-term follow-upFollow-up periodLow incidence of infectionIncidence of infectionMicra patientsSystem revisionMajor complicationsComplication ratePAR patientsEfficacy profileLow incidenceTransvenous systemsDevice upgradeComparison of Outcomes of Hematopoietic Cell Transplantation (HCT) for Asymptomatic Patients with Sickle Cell Disease (SCD) and That of Propensity Matched Symptomatic Patients Undergoing HCT
Katoch D, Nallagatla V, Liang J, Deng Y, Krishnamurti L. Comparison of Outcomes of Hematopoietic Cell Transplantation (HCT) for Asymptomatic Patients with Sickle Cell Disease (SCD) and That of Propensity Matched Symptomatic Patients Undergoing HCT. Transplantation And Cellular Therapy 2024, 30: s65. DOI: 10.1016/j.jtct.2023.12.103.Peer-Reviewed Original ResearchHematopoietic cell transplantationOutcomes of hematopoietic cell transplantationSickle cell diseaseSymptomatic SCD patientsAsymptomatic patientsDonor typeSymptomatic patientsPost-HCTSCD patientsHematopoietic cell transplantation comorbidity indexPost-transplant lymphoproliferative disorderMedian follow-up periodComplication of sickle cell diseaseIncidence of aGVHDReduced intensity conditioningSickle cell disease patientsFollow-up periodPropensity-matched modelStandardized mean differenceSecondary malignanciesLymphoproliferative disordersCell transplantationGraft survivalPatient ageAssociated with group classification
2023
Breastfeeding and impact on childhood hospital admissions: a nationwide birth cohort in South Korea
Lee J, Shin J, Kim S, Choi Y, Shin Y, Hwang J, Shin J, Koyanagi A, Jacob L, Smith L, Jeong H, Noh Y, Oh I, Rhee S, Min C, Cho S, Turner S, Fond G, Boyer L, Suh D, Acharya K, Shin J, Lee S, Yon D. Breastfeeding and impact on childhood hospital admissions: a nationwide birth cohort in South Korea. Nature Communications 2023, 14: 5819. PMID: 37730734, PMCID: PMC10511528, DOI: 10.1038/s41467-023-41516-y.Peer-Reviewed Original ResearchConceptsNationwide birth cohortMedian follow-up periodProtective effectProtective effect of breastfeedingBirth cohortAssociation of breastfeedingHospital admissionFollow-up periodEffect of breastfeedingChildhood hospital admissionsApparent protective effectHospital admission ratesPublic health strategiesOverall child healthFormula feedingHealth strategiesChild healthBreastfeedingAdmission ratesIncreasing ageInfantsCohortAdmissionHospitalChildren
2022
Dietary glycemic index, glycemic load, and cause-specific mortality: two population-based prospective cohort studies
Zhao L, Li H, Liu D, Fang J, Wang J, Tan Y, Xiang Y. Dietary glycemic index, glycemic load, and cause-specific mortality: two population-based prospective cohort studies. European Journal Of Clinical Nutrition 2022, 76: 1142-1149. PMID: 35105945, PMCID: PMC9339588, DOI: 10.1038/s41430-022-01083-9.Peer-Reviewed Original ResearchConceptsRisk of CVD mortalityCause-specific mortalityAssociated with lower riskDietary GICVD mortalityGlycemic loadAll-CauseIncreased risk of CVD mortalityHigher risk of CVD mortalityCardiovascular diseaseHazard ratioHigh risk of cardiovascular diseaseFood frequency questionnaireRisk of cardiovascular diseaseProspective cohort studyHigh riskLow riskDietary glycemic indexCancer mortalityCohort-specific food frequency questionnairesDietary GLFrequency questionnaireChinese adultsMedian follow-up periodPotential confounders
2021
Moderate alcohol intake associates with a decreased risk of venous thrombosis: mediation through decreased stress-associated brain activity
Mezue K, Osborne M, Abbasi T, Zureigat H, Abohashem S, Gharios C, Akuffo E, Cardeiro A, Pitman R, Shin L, Jaffer F, Rosovsky R, Tawakol A. Moderate alcohol intake associates with a decreased risk of venous thrombosis: mediation through decreased stress-associated brain activity. European Heart Journal 2021, 42: ehab724.2046. DOI: 10.1093/eurheartj/ehab724.2046.Peer-Reviewed Original ResearchModerate alcohol intakeDeep venous thrombosisAlcohol intakeNeural activityEffects of alcoholEffects of moderate alcoholVenous thrombosisDecreased riskNeural effectsMedian follow-up periodDeep venous thrombosis riskBrain activityMediation analysisRisk of deep venous thrombosisIncidence of deep venous thrombosisRisk of venous thrombosisDecreased risk of venous thrombosisAdult participantsEmission Tomography ImagingCox regression analysisFollow-up periodNeural pathwaysNeurobiological activityFollow-up outcome informationModerate alcoholAnxiety and depression associate with heightened risk of deep venous thrombosis: mediation through neural pathways
Mezue K, Osborne M, Abohashem S, Zureigat H, Abbasi T, Gharios C, Cardeiro A, Akuffo E, Pitman R, Shin L, Jaffer F, Rosovsky R, Tawakol A. Anxiety and depression associate with heightened risk of deep venous thrombosis: mediation through neural pathways. European Heart Journal 2021, 42: ehab724.2045. DOI: 10.1093/eurheartj/ehab724.2045.Peer-Reviewed Original ResearchAnxiety disordersInternational Classification of DiseasesRisk of deep venous thrombosisDeep venous thrombosisNeural activityNeural pathwaysFollow-up periodMass General Brigham BiobankIncreased riskClassification of diseasesBiobank enrollmentVenous thrombosisIncreased risk of DVTCancer historyIncreased risk of deep venous thrombosisHealth informationMediation analysisDeep venous thrombosis riskInternational ClassificationMedian follow-up periodPotential confoundersAnxietyLower extremity deep venous thrombosisExtremity deep venous thrombosisDepression
2018
Immediate Postablation 18F-FDG Injection and Corresponding SUV Are Surrogate Biomarkers of Local Tumor Progression After Thermal Ablation of Colorectal Carcinoma Liver Metastases
Cornelis F, Petre E, Vakiani E, Klimstra D, Durack J, Gonen M, Osborne J, Solomon S, Sofocleous C. Immediate Postablation 18F-FDG Injection and Corresponding SUV Are Surrogate Biomarkers of Local Tumor Progression After Thermal Ablation of Colorectal Carcinoma Liver Metastases. Journal Of Nuclear Medicine 2018, 59: 1360-1365. PMID: 29439012, PMCID: PMC6126442, DOI: 10.2967/jnumed.117.194506.Peer-Reviewed Original ResearchConceptsLocal tumor progressionContrast-enhanced CT imagesSUV ratioTumor progressionPostablation biopsiesLiver metastasesTumor cellsAblation of colorectal liver metastasesPredictor of local tumor progressionInstitutional review board-approved prospective studyLocal tumor progression rateMargin sizeMedian follow-up periodColorectal carcinoma liver metastasesCompeting-risks regression modelsTumor-negative biopsiesCT imagesF-FDG PET/CTTumor progression rateColorectal liver metastasesCompeting-risk analysisFollow-up periodTumor-positive biopsiesSurrounding normal liverSubdistribution hazard ratios
2017
Risk-adjusted adverse outcomes in complex abdominal wall hernia repair with biologic mesh: A case series of 140 patients
Latifi R, Samson D, Haider A, Azim A, Iftikhar H, Joseph B, Tilley E, Con J, Gashi S, El-Menyar A. Risk-adjusted adverse outcomes in complex abdominal wall hernia repair with biologic mesh: A case series of 140 patients. International Journal Of Surgery 2017, 43: 26-32. PMID: 28526657, DOI: 10.1016/j.ijsu.2017.05.031.Peer-Reviewed Original ResearchConceptsAbdominal wall hernia repairBiologic meshComplex abdominal wall hernia repairUrgent surgeryHernia repairAdverse outcomesHigh risk of wound infectionMedian follow-up periodPredictor of adverse outcomesRetrospective case series studyRisk of wound infectionType of surgeryTertiary medical centerCase series studyFollow-up periodMean hospital lengthRisk-adjusted adverse outcomesMesh placement techniqueMesh removalWound complicationsWound infectionCase seriesHernia recurrenceHospital lengthPorcine mesh
2016
Endoscopic balloon dilation in the management of strictures in Crohn’s disease: a systematic review and meta-analysis of non-randomized trials
Navaneethan U, Lourdusamy V, Njei B, Shen B. Endoscopic balloon dilation in the management of strictures in Crohn’s disease: a systematic review and meta-analysis of non-randomized trials. Surgical Endoscopy 2016, 30: 5434-5443. PMID: 27126619, DOI: 10.1007/s00464-016-4902-1.Peer-Reviewed Original ResearchConceptsEndoscopic balloon dilationSurgical intervention rateRisk of surgical interventionManagement of Crohn’s stricturesIntervention ratesPrimary stricturesCrohn's stricturesBalloon dilationSurgical interventionAdverse eventsMethodsA comprehensive search of MEDLINEDecreased riskTreated with endoscopic balloon dilationMedian follow-up periodDilatation of anastomotic stricturesSafety of endoscopic balloon dilationAssociated with strictureComprehensive search of MEDLINEFollow-up periodDiagnosis of CDMethodsA comprehensive searchNon-randomized trialsSystematic reviewManagement of stricturesPrimary outcome measure
2011
Accurate Staging for Gallbladder Cancer
Ito H, Ito K, D'Angelica M, Gonen M, Klimstra D, Allen P, DeMatteo R, Fong Y, Blumgart L, Jarnagin W. Accurate Staging for Gallbladder Cancer. Annals Of Surgery 2011, 254: 320-325. PMID: 21617582, DOI: 10.1097/sla.0b013e31822238d8.Peer-Reviewed Original ResearchConceptsTotal lymph node countDisease-specific survivalLiver involvementT2 tumorsLymph nodesSurgical treatmentAssociated with decreased recurrence-freeMedian total lymph node countTNM stageAssociated with liver involvementMedian follow-up periodAdjacent organ resectionHistologic tumor involvementResidual liver diseaseT-stage tumorsDefinitive surgical treatmentLymph node countAdequate surgical treatmentSurvival of patientsInvolvement of liverRegional lymph nodesFollow-up periodAssociated with outcomeLN dissectionNodal involvement
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply