Publications

Featured Publications

Real-World Evidence Synthesis of Digital Scribes Using Ambient Listening and Generative Artificial Intelligence for Clinician Documentation Workflows: Rapid Review
Kanaparthy N, Villuendas-Rey Y, Bakare T, Diao Z, Iscoe M, Loza A, Wright D, Safranek C, Faustino I, Brackett A, Melnick E, Taylor R. Real-World Evidence Synthesis of Digital Scribes Using Ambient Listening and Generative Artificial Intelligence for Clinician Documentation Workflows: Rapid Review. JMIR AI 2025, 4: e76743. PMID: 41071988, PMCID: PMC12513689, DOI: 10.2196/76743.
Peer-Reviewed Original Research
Concepts
Extracting language information from clinical notes using large language models
Qian L, Hong N, Zhou Y, Xie Q, Weng R, Chairuengjitjaras P, Du X, Lian J, Marshall G, Blackley S, Novoa-Laurentiev J, Quiroz Y, Kim T, Adams N, Dossett M, Zhou L, Xu H. Extracting language information from clinical notes using large language models. International Journal Of Medical Informatics 2025, 205: 106116. PMID: 40992205, PMCID: PMC12490899, DOI: 10.1016/j.ijmedinf.2025.106116.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Integrating rule-based NLP and large language models for statin information extraction from clinical notes
Liu S, McCoy A, Chen Q, Wright A. Integrating rule-based NLP and large language models for statin information extraction from clinical notes. International Journal Of Medical Informatics 2025, 205: 106104. PMID: 40925145, DOI: 10.1016/j.ijmedinf.2025.106104.
Peer-Reviewed Original Research
Concepts
Multimodal Imaging to Improve Patient Selection and Optimize Treatment Planning and Delivery for Patients Undergoing Reirradiation: A Scoping Review
Beddok A, Rozenblum L, Calugaru V, Feuvret L, Champion L, Eddine C, Crehange G, El Fakhri G, Buvat I. Multimodal Imaging to Improve Patient Selection and Optimize Treatment Planning and Delivery for Patients Undergoing Reirradiation: A Scoping Review. Current Oncology Reports 2025, 1-15. PMID: 40830323, DOI: 10.1007/s11912-025-01708-9.
Peer-Reviewed Original Research
Concepts
Polygenic Resistance to Blood Pressure Treatment and Stroke Risk: Insights from the All of Us Research Program
Huo S, Rivier C, Clocchiatti‐Tuozzo S, Renedo D, Petersen N, de Havenon A, Meeker D, Zhao H, Ohno‐Machado L, Sheth K, Falcone G. Polygenic Resistance to Blood Pressure Treatment and Stroke Risk: Insights from the All of Us Research Program. Annals Of Neurology 2025 PMID: 40827941, DOI: 10.1002/ana.78009.
Peer-Reviewed Original Research
Concepts
Usability and adoption in a randomized trial of GutGPT a GenAI tool for gastrointestinal bleeding
Chung S, Giuffrè M, Rajashekar N, Pu Y, Shin Y, Kresevic S, Chan C, Nakamura-Sakai S, You K, Saarinen T, Hsiao A, Wong A, Evans L, McCall T, Kizilcec R, Sekhon J, Laine L, Shung D. Usability and adoption in a randomized trial of GutGPT a GenAI tool for gastrointestinal bleeding. Npj Digital Medicine 2025, 8: 527. PMID: 40825997, PMCID: PMC12361555, DOI: 10.1038/s41746-025-01896-5.
Peer-Reviewed Original Research
Concepts
Molecular characterization of Kawasaki disease subgroups using cell-free RNA profiling
Loy C, Wang H, Kim J, Shimizu C, Lenz J, Belcher E, Tremoulet A, Burns J, De Vlaminck I. Molecular characterization of Kawasaki disease subgroups using cell-free RNA profiling. Scientific Reports 2025, 15: 29799. PMID: 40813796, PMCID: PMC12354920, DOI: 10.1038/s41598-025-15843-7.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Multi-modal clustering reveals event-free patient subgroup in colorectal cancer survival
Janakarajan N, Larghero G, Rodríguez Martínez M. Multi-modal clustering reveals event-free patient subgroup in colorectal cancer survival. Npj Systems Biology And Applications 2025, 11: 86. PMID: 40753169, PMCID: PMC12318085, DOI: 10.1038/s41540-025-00557-3.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
False-positive tolerant model misconduct mitigation in distributed federated learning on electronic health record data across clinical institutions
Edelson M, Pham A, Kuo T. False-positive tolerant model misconduct mitigation in distributed federated learning on electronic health record data across clinical institutions. Scientific Reports 2025, 15: 23310. PMID: 40603924, PMCID: PMC12223104, DOI: 10.1038/s41598-025-04069-2.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
475 Calibrating Diagnostic Errors: The Emergence of a Diagnostic “Gray” Zone
Pavuluri S, Sangal R, Venkatesh A, Taylor R, Sather J. 475 Calibrating Diagnostic Errors: The Emergence of a Diagnostic “Gray” Zone. Annals Of Emergency Medicine 2025, 86: s204. DOI: 10.1016/j.annemergmed.2025.06.494.
Peer-Reviewed Original Research
Predicting tumor recurrence site after reirradiation in head and neck cancer: a retrospective external validation of a published [18F]-FDG PET radiomic signature
Beddok A, Grogg K, Nioche C, Rozenblum L, Orlhac F, Calugaru V, Crehange G, Shih H, Marin T, Buvat I, El Fakhri G. Predicting tumor recurrence site after reirradiation in head and neck cancer: a retrospective external validation of a published [18F]-FDG PET radiomic signature. La Radiologia Medica 2025, 1-10. PMID: 40833475, DOI: 10.1007/s11547-025-02072-1.
Peer-Reviewed Original Research
Concepts
A Measurement Science Framework to Optimize CDS for Opioid Use Disorder Treatment in the ED
Iscoe M, Hooper C, Levy D, Lutz J, Paek H, Rose C, Kannampallil T, Meeker D, Dziura J, Melnick E. A Measurement Science Framework to Optimize CDS for Opioid Use Disorder Treatment in the ED. Applied Clinical Informatics 2025, 16: 1067-1076. PMID: 40834872, PMCID: PMC12431813, DOI: 10.1055/a-2595-0317.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
In vivo 3D myocardial membrane potential mapping in humans using PET/MRI
Bijari F, Han P, Marin T, Lee W, Chemli Y, Gertsenshteyn I, Mounime I, Djebra Y, Chi D, Normandin M, Ma C, Fakhri G. In vivo 3D myocardial membrane potential mapping in humans using PET/MRI. EJNMMI Research 2025, 15: 93. PMID: 40715686, PMCID: PMC12297085, DOI: 10.1186/s13550-025-01287-7.
Peer-Reviewed Original Research
Concepts
Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review)
Manoharan S, Iyappan O, Prabahar A, Bhasuran B, Raja K. Gut‑lung axis microbiome: Towards precision medicine in respiratory disorders (Review). World Academy Of Sciences Journal 2025, 7: 1-15. DOI: 10.3892/wasj.2025.376.
Peer-Reviewed Original Research
AI Workflow, External Validation, and Development in Eye Disease Diagnosis
Chen Q, Keenan T, Agron E, Allot A, Guan E, Duong B, Elsawy A, Hou B, Xue C, Bhandari S, Broadhead G, Cousineau-Krieger C, Davis E, Gensheimer W, Golshani C, Grasic D, Gupta S, Haddock L, Konstantinou E, Lamba T, Maiberger M, Mantopoulos D, Mehta M, Elnahry A, AL-Nawaflh M, Oshinsky A, Powell B, Purt B, Shin S, Stiefel H, Thavikulwat A, Wroblewski K, Tham Y, Cheung C, Cheng C, Chew E, Hribar M, Chiang M, Lu Z. AI Workflow, External Validation, and Development in Eye Disease Diagnosis. JAMA Network Open 2025, 8: e2517204. PMID: 40668583, PMCID: PMC12268484, DOI: 10.1001/jamanetworkopen.2025.17204.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

2025

Divergent proteome tolerance against gain and loss of chromosome arms.
Di Y, Li W, Castellano JJ, Jin W, Modi JN, Salovska B, Khosroabadi D, Hu W, Taylor AM, Liu Y. Divergent proteome tolerance against gain and loss of chromosome arms. Mol Cell 2025, 85: 4268-4278.e6. PMID: 41270725, DOI: 10.1016/j.molcel.2025.10.023.
Peer-Reviewed Original Research
Sequential class switching generates antigen-specific gut IgA from IgG1 B cells
Siniscalco E, Meng H, Gabernet G, Pacheco G, Saghaei S, Ramirez S, Hills L, Faraji F, Chen S, Yin X, Dien C, Hoyt L, Liu E, Barrett A, Briggs N, Williams A, Shukla V, Crotty S, Wesemann D, Kleinstein S, Craft J, Eisenbarth S. Sequential class switching generates antigen-specific gut IgA from IgG1 B cells. Immunity 2025 PMID: 41253159, DOI: 10.1016/j.immuni.2025.10.022.
Peer-Reviewed Original Research
This study investigates how gut-specific IgA antibodies are generated from IgG1 B cells through sequential class switching, highlighting a crucial mechanism for designing effective mucosal vaccines.
Full Summary
Digital Health Tool for Preventing Blindness From Diabetic Retinopathy: Protocol for a Qualitative Study.
Frimpong A, Granados A, Chang T, Fu J, Applebaum SS, Moore SG, Kaur M, Adepoju B, Hari Krishnan V, Levi A, McCall T, Nwanyanwu KH. Digital Health Tool for Preventing Blindness From Diabetic Retinopathy: Protocol for a Qualitative Study. JMIR Res Protoc 2025, 14: e65894. PMID: 41223405, DOI: 10.2196/65894.
Peer-Reviewed Original Research
Pancreatic Ductal Adenocarcinoma After Hepatitis C Infection.
Levinson RN, Bushman R, Tate JP, Skanderson M, Mezzacappa C, Park LS, Brandt CA, Schuster KM, Ketwaroo GA, Yang YX, Justice AC, Wang LL. Pancreatic Ductal Adenocarcinoma After Hepatitis C Infection. JAMA Netw Open 2025, 8: e2543701. PMID: 41236736, DOI: 10.1001/jamanetworkopen.2025.43701.
Peer-Reviewed Original Research
Understanding the Comorbidities Among Psychiatric Disorders, Chronic Low Back Pain, and Spinal Degenerative Disease Using Observational and Genetically Informed Analyses
Qiu D, Friligkou E, He J, Cabrera-Mendoza B, Aslan M, Gupta M, Polimanti R. Understanding the Comorbidities Among Psychiatric Disorders, Chronic Low Back Pain, and Spinal Degenerative Disease Using Observational and Genetically Informed Analyses. Biological Psychiatry Global Open Science 2025, 5: 100588. DOI: 10.1016/j.bpsgos.2025.100588.
Peer-Reviewed Original Research
Concepts
AgentMD: Empowering language agents for risk prediction with large-scale clinical tool learning
Jin Q, Wang Z, Yang Y, Zhu Q, Wright D, Huang T, Khandekar N, Wan N, Ai X, Wilbur W, He Z, Taylor R, Chen Q, Lu Z. AgentMD: Empowering language agents for risk prediction with large-scale clinical tool learning. Nature Communications 2025, 16: 9377. PMID: 41130954, PMCID: PMC12549800, DOI: 10.1038/s41467-025-64430-x.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Evaluating a Disease-Specific Look-Back Trigger Methodology Versus Traditional Screening for Diagnostic Errors in the Emergency Department
Pavuluri S, Sangal R, Rothenberg C, Venkatesh A, Taylor R, Sather J. Evaluating a Disease-Specific Look-Back Trigger Methodology Versus Traditional Screening for Diagnostic Errors in the Emergency Department. The Joint Commission Journal On Quality And Patient Safety 2025 PMID: 41238461, DOI: 10.1016/j.jcjq.2025.10.002.
Peer-Reviewed Original Research
Concepts
Impact of chiropractic care on opioid use for non-cancer spine pain: systematic review and meta-analysis
Emary PC, Corcoran KL, Coleman BC, Brown AL, Ciraco C, DiDonato J, Wang L, Couban RJ, Sud A, Busse JW. Impact of chiropractic care on opioid use for non-cancer spine pain: systematic review and meta-analysis. PAIN Reports [Accepted - In Press]
Peer-Reviewed Original Research In Press
Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer
Westvold S, Long J, Fan J, Kc M, Hyslop T, Conlin K, Jacobson S, Silber A, Wang S, Leapman M, Leeds I, Spees L, Wheeler S, Gross C, Oeffinger K, Dinan M. Cardiovascular risk in long-term survivors of breast, prostate, colon, and rectal cancer. Journal Of The National Cancer Institute 2025, djaf243. PMID: 41069232, DOI: 10.1093/jnci/djaf243.
Peer-Reviewed Original Research
This study investigates cardiovascular risk in older long-term cancer survivors, showing non-cancer factors, rather than cancer-specific ones, predict late-onset cardiovascular disease.
Full Summary
Psychosocial Risk Factors and Perceived Well‐Being in Survivors of Gastrointestinal Cancer
Butensky S, Schultz K, Godfrey E, Kim J, Sanft T, Johnson C, Leeds I, Khan S. Psychosocial Risk Factors and Perceived Well‐Being in Survivors of Gastrointestinal Cancer. Psycho-Oncology 2025, 34: e70302. PMID: 41068065, DOI: 10.1002/pon.70302.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

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