2024
Pre-scan state anxiety is associated with greater right amygdala-hippocampal response to fearful versus happy faces among trait-anxious Latina girls
Díaz D, Tseng W, Michalska K. Pre-scan state anxiety is associated with greater right amygdala-hippocampal response to fearful versus happy faces among trait-anxious Latina girls. BMC Psychiatry 2024, 24: 1. PMID: 38167015, PMCID: PMC10759434, DOI: 10.1186/s12888-023-05403-6.Peer-Reviewed Original ResearchConceptsState anxietyTrait anxietyHappy facesEmotion processingLatina girlsImplicit emotion processingNon-anxious youthHigh trait anxietyFearful facial affectFearful facesEmotional valenceFacial affectNeural correlatesIndividual differencesBrain activationBrain responsesNeural activationReduced engagementCommunity sampleAnxietyInteractive effectsHigh levelsGirlsMethodsThe present studySystematic differences
2017
Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology
Stoddard J, Tseng WL, Kim P, Chen G, Yi J, Donahue L, Brotman MA, Towbin KE, Pine DS, Leibenluft E. Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology. JAMA Psychiatry 2017, 74: 95-103. PMID: 27902832, PMCID: PMC6309540, DOI: 10.1001/jamapsychiatry.2016.3282.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaAnxiety DisordersArousalAttention Deficit Disorder with HyperactivityBrainChildCross-Sectional StudiesDominance, CerebralEmotionsFacial RecognitionFemaleHumansIrritable MoodMagnetic Resonance ImagingMaleMental DisordersMood DisordersNerve NetPrefrontal CortexPsychopathologyConceptsFunctional magnetic resonance imagingPrefrontal cortex connectivityFace emotionsNeural responsesCortex connectivityMedial prefrontal cortex connectivityAttention-deficit/hyperactivity disorderChild Anxiety Related DisordersThreat-related facesDisruptive Mood DysregulationPathophysiology of irritabilityFace emotion processingAmygdala-medial prefrontal cortex connectivityCross-sectional functional magnetic resonanceAffective Reactivity IndexBrain-behavior relationshipsVentral visual areasAssociations of irritabilityUnique effectsAmygdala functional connectivityAnxiety Related DisordersFunctional magnetic resonanceYouth ages 8Angry facesFearful faces
2016
Functional connectivity during masked and unmasked face emotion processing in bipolar disorder
Tseng WL, Thomas LA, Harkins E, Stoddard J, Zarate CA, Pine DS, Leibenluft E, Brotman MA. Functional connectivity during masked and unmasked face emotion processing in bipolar disorder. Psychiatry Research Neuroimaging 2016, 258: 1-9. PMID: 27814457, PMCID: PMC5135603, DOI: 10.1016/j.pscychresns.2016.10.006.Peer-Reviewed Original ResearchConceptsFace emotion processingEmotion processingHealthy volunteersBipolar disorderFunctional connectivityAffective priming taskAmygdala-vmPFC connectivityVentromedial prefrontal cortexExpression of emotionsBD patientsMedial frontal gyrusNeutral facesPriming taskEmotion typeEmotional processingFMRI scanningActivation differencesFrontal gyrusGreater activationLess activationPrefrontal cortexConnectivity findingsNeural connectivityPathophysiological correlatesNeural dysfunction
2015
Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation
Tseng WL, Thomas LA, Harkins E, Pine DS, Leibenluft E, Brotman MA. Neural correlates of masked and unmasked face emotion processing in youth with severe mood dysregulation. Social Cognitive And Affective Neuroscience 2015, 11: 78-88. PMID: 26137973, PMCID: PMC4692312, DOI: 10.1093/scan/nsv087.Peer-Reviewed Original ResearchConceptsSevere mood dysregulationFace emotion processingFunctional magnetic resonance imagingEmotion processingParahippocampal gyrusNeural correlatesMood dysregulationVentromedial prefrontal cortex activationAffective priming paradigmPrefrontal cortex activationSuperior temporal gyrusAngry facesFace processingHappy facesSMD patientsPositive emotionsPriming paradigmVmPFC dysfunctionNegative emotionsTemporal gyrusCortex activationEmotionsFMRI dataDecreased activationIndependent samplesAn fMRI study of emotional face encoding in youth at risk for bipolar disorder
Tseng W, Bones BL, Kayser RR, Olsavsky AK, Fromm SJ, Pine DS, Leibenluft E, Brotman MA. An fMRI study of emotional face encoding in youth at risk for bipolar disorder. European Psychiatry 2015, 30: 94-98. PMID: 25172156, PMCID: PMC10656053, DOI: 10.1016/j.eurpsy.2014.05.004.Peer-Reviewed Original Research
2014
Borderline personality features as a predictor of forms and functions of aggression during middle childhood: Examining the roles of gender and physiological reactivity
Banny AM, Tseng WL, Murray-Close D, Pitula CE, Crick NR. Borderline personality features as a predictor of forms and functions of aggression during middle childhood: Examining the roles of gender and physiological reactivity. Development And Psychopathology 2014, 26: 789-804. PMID: 25047299, DOI: 10.1017/s095457941400039x.Peer-Reviewed Original ResearchConceptsPhysiological reactivityRelational aggressionBorderline personalityProactive relational aggressionReactive relational aggressionProactive physical aggressionFunctions of aggressionSkin conductance reactivitySelf-report measuresAggressive behaviorPresent longitudinal investigationBorderline personality featuresRelational stressorsEmotional dysregulationInterpersonal stressRole of genderLaboratory stress protocolMiddle childhoodPhysical aggressionPersonality featuresLongitudinal investigationPath analysisPersonalityAggressionStress protocol
2013
A Systems Neuroscience Approach to the Pathophysiology of Pediatric Mood and Anxiety Disorders
Tseng WL, Leibenluft E, Brotman MA. A Systems Neuroscience Approach to the Pathophysiology of Pediatric Mood and Anxiety Disorders. 2013, 16: 297-317. PMID: 24281907, PMCID: PMC4482127, DOI: 10.1007/7854_2013_252.Peer-Reviewed Original ResearchConceptsPediatric moodAnxiety disordersFunctional magnetic resonance imaging (fMRI) researchSystems neuroscience approachMagnetic resonance imaging researchNeuroscience approachEmotional dysregulationNeural mechanismsBehavioral findingsCore featuresImaging researchMoodFuture researchPotential novel treatmentDisordersNovel treatmentsResearchBrainFindingsChapterPathophysiologyRelationshipDysregulationAbnormalities