Featured Publications
Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis
Ahmadzai N, Cheng W, Kilty S, Esmaeilisaraji L, Wolfe D, Bonaparte J, Schramm D, Fitzpatrick E, Lin V, Skidmore B, Hutton B. Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis. PLOS ONE 2020, 15: e0237523. PMID: 32870918, PMCID: PMC7462264, DOI: 10.1371/journal.pone.0237523.Peer-Reviewed Original ResearchConceptsComplete vertigo controlEndolymphatic sac decompressionRandomized clinical trialsEndolymphatic duct blockageIT steroidsVertigo controlMeniere's diseaseIT gentamicinSurgical interventionSystematic reviewKey patient outcomesHigh cumulative dosageBest treatment optionSensorineural hearing lossEDB groupESD groupAural fullnessIntratympanic gentamicinSteroid injectionVertigo attacksHead trialsHearing preservationSurgical therapyCochrane LibraryCumulative dosage
2022
Accuracy of presenting symptoms, physical examination, and imaging for diagnosis of ruptured abdominal aortic aneurysm: Systematic review and meta‐analysis
Fernando SM, Tran A, Cheng W, Rochwerg B, Strauss SA, Mutter E, McIsaac DI, Kyeremanteng K, Kubelik D, Jetty P, Nagpal SK, Thiruganasambandamoorthy V, Roberts DJ, Perry JJ. Accuracy of presenting symptoms, physical examination, and imaging for diagnosis of ruptured abdominal aortic aneurysm: Systematic review and meta‐analysis. Academic Emergency Medicine 2022, 29: 486-496. PMID: 35220634, DOI: 10.1111/acem.14475.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysmAortic aneurysmRuptured abdominal aortic aneurysmPooled sensitivityCases of rAAADiagnosis of AAAPhysical examination signsEarly surgical interventionLife-threatening conditionClassic clinical symptomsReference standardExamination signsAbdominal painAbdominal massVascular centersBack painClinical symptomsSurgical interventionPhysical examinationIntraoperative diagnosisUrgent transferCare ultrasoundRAAACTA diagnosisSystematic review
2019
Pharmacologic and surgical therapies for patients with Meniere’s disease: a protocol for a systematic review and meta-analysis
Ahmadzai N, Cheng W, Wolfe D, Bonaparte J, Schramm D, Fitzpatrick E, Lin V, Skidmore B, Esmaeilisaraji L, Kilty S, Hutton B. Pharmacologic and surgical therapies for patients with Meniere’s disease: a protocol for a systematic review and meta-analysis. Systematic Reviews 2019, 8: 341. PMID: 31888735, PMCID: PMC6937806, DOI: 10.1186/s13643-019-1195-1.Peer-Reviewed Original ResearchConceptsSensorineural hearing lossMeniere's diseaseQuality of lifeSystematic reviewHearing-related disabilitySeverity of vertigoAttacks of vertigoIntractable Meniere's diseaseKey clinical trialsIntensity of tinnitusPre-specified eligibility criteriaCause of disabilityClinical treatment strategiesPlanned systematic reviewElectronic search strategyOptimal clinical treatment strategiesMedical information specialistBackgroundHearing lossVertigo attacksCochrane riskSurgical therapyBias toolSurgical interventionCochrane LibraryFuture trials