Muscarinic antagonists impair multiple aspects of operant discrimination learning and performance
Yousuf H, Girardi E, Crouse R, Picciotto M. Muscarinic antagonists impair multiple aspects of operant discrimination learning and performance. Neuroscience Letters 2022, 794: 137025. PMID: 36529388, PMCID: PMC9812939, DOI: 10.1016/j.neulet.2022.137025.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsConditioning, OperantDiscrimination LearningLearningMemoryMiceMuscarinic AntagonistsReceptors, MuscarinicRewardScopolamineConceptsOperant discriminationOperant discrimination learningCue-reward associationsLong-term memoryMultiple training sessionsPost-session injectionsCue associationsReward-related respondingMemory processesDiscrimination learningMaladaptive formsImpaired consolidationFood rewardSuccessful learningNose pokesDifferent learningPre-session injectionsTraining sessionsRewardTaskMemoryLearningMultiple aspectsEnvironmental cuesMuscarinic acetylcholine receptor family