Featured Publications
Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning
Kucukkaya A, Zeevi T, Chai N, Raju R, Haider S, Elbanan M, Petukhova-Greenstein A, Lin M, Onofrey J, Nowak M, Cooper K, Thomas E, Santana J, Gebauer B, Mulligan D, Staib L, Batra R, Chapiro J. Predicting tumor recurrence on baseline MR imaging in patients with early-stage hepatocellular carcinoma using deep machine learning. Scientific Reports 2023, 13: 7579. PMID: 37165035, PMCID: PMC10172370, DOI: 10.1038/s41598-023-34439-7.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularHumansLiver NeoplasmsMachine LearningMagnetic Resonance ImagingNeoplasm Recurrence, LocalRetrospective StudiesOutcomes of Simultaneous Liver‐Kidney Transplantation Using Kidneys of Deceased Donors With Acute Kidney Injury
Batra RK, Ariyamuthu VK, MacConmara MP, Gupta G, Gungor AB, Tanriover B. Outcomes of Simultaneous Liver‐Kidney Transplantation Using Kidneys of Deceased Donors With Acute Kidney Injury. Liver Transplantation 2022, 28: 983-997. PMID: 35006615, DOI: 10.1002/lt.26406.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryGraft SurvivalHumansKidneyKidney TransplantationLiverLiver TransplantationRetrospective StudiesTissue DonorsConceptsSimultaneous liver-kidney transplantationDeath-censored graft failureAcute kidney injuryLiver-kidney transplantationDeceased donorsKidney injuryGraft failureSCr levelsMultivariable Cox proportional hazards modelsTerminal serum creatinine levelTransplantation Network registry dataCox proportional hazards modelShorter cold ischemia timeCause graft failureGood organ qualitySerum creatinine levelsCold ischemia timeInternational consensus guidelinesProportional hazards modelLiver transplantCreatinine levelsPrimary outcomeStudy cohortIschemia timeKidney diseaseMachine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study.
Iseke S, Zeevi T, Kucukkaya AS, Raju R, Gross M, Haider SP, Petukhova-Greenstein A, Kuhn TN, Lin M, Nowak M, Cooper K, Thomas E, Weber MA, Madoff DC, Staib L, Batra R, Chapiro J. Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study. American Journal Of Roentgenology 2022, 220: 245-255. PMID: 35975886, PMCID: PMC10015590, DOI: 10.2214/ajr.22.28077.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularFemaleHumansLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesRisk FactorsConceptsEarly-stage hepatocellular carcinomaLiver transplantHepatocellular carcinomaImaging featuresPosttreatment recurrenceOrgan allocationMean AUCLiver transplant eligibilityPretreatment clinical characteristicsPretreatment MRI examinationsKaplan-Meier analysisKaplan-Meier curvesClinical characteristicsImaging surveillanceTherapy allocationTransplant eligibilityUnderwent treatmentClinical parametersRetrospective studyUnpredictable complicationMRI dataConcept studyPoor survivalClinical impactPretreatment MRIDeep learning–assisted differentiation of pathologically proven atypical and typical hepatocellular carcinoma (HCC) versus non-HCC on contrast-enhanced MRI of the liver
Oestmann PM, Wang CJ, Savic LJ, Hamm CA, Stark S, Schobert I, Gebauer B, Schlachter T, Lin M, Weinreb JC, Batra R, Mulligan D, Zhang X, Duncan JS, Chapiro J. Deep learning–assisted differentiation of pathologically proven atypical and typical hepatocellular carcinoma (HCC) versus non-HCC on contrast-enhanced MRI of the liver. European Radiology 2021, 31: 4981-4990. PMID: 33409782, PMCID: PMC8222094, DOI: 10.1007/s00330-020-07559-1.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularContrast MediaDeep LearningHumansLiver NeoplasmsMagnetic Resonance ImagingRetrospective StudiesConceptsNon-HCC lesionsHepatocellular carcinomaHCC lesionsAtypical imagingGrading systemLI-RADS criteriaAtypical imaging featuresPrimary liver cancerTypical hepatocellular carcinomaAtypical hepatocellular carcinomaContrast-enhanced MRISensitivity/specificityLiver transplantMethodsThis IRBRetrospective studyLiver malignanciesImaging featuresLiver cancerAtypical featuresConclusionThis studyLesionsMRIClinical applicationCarcinomaImage-based diagnosis
2020
Fibronodular hepatocellular carcinoma—a new variant of liver cancer: clinical, pathological and radiological correlation
Tefera J, Revzin M, Chapiro J, Savic L, Mulligan D, Batra R, Taddei T, Jain D, Zhang X. Fibronodular hepatocellular carcinoma—a new variant of liver cancer: clinical, pathological and radiological correlation. Journal Of Clinical Pathology 2020, 74: 31-35. PMID: 32430483, PMCID: PMC7674234, DOI: 10.1136/jclinpath-2020-206574.Peer-Reviewed Original ResearchConceptsAdvanced Barcelona Clinic Liver Cancer stageBarcelona Clinic Liver Cancer stageScirrhous HCCMultiple rounded nodulesNon-peripheral washoutLiver Cancer stageRadiological featuresClinical featuresRadiological correlationCarcinoma variantsCancer stageHCC casesHepatocellular carcinomaLiver cancerFibrotic liverConventional HCCHCCLower ratesHigh rateRounded nodulesProgressionDistinct patternsCarcinomaSpecific variantsLesions
2015
Rapid Resolution of Donor‐Derived Glomerular Fibrin Thrombi After Deceased Donor Kidney Transplantation
Batra R, Heilman R, Smith M, Thomas L, Khamash H, Katariya N, Hewitt W, Singer A, Mathur A, Huskey J, Chakkera H, Moss A, Reddy K. Rapid Resolution of Donor‐Derived Glomerular Fibrin Thrombi After Deceased Donor Kidney Transplantation. American Journal Of Transplantation 2015, 16: 1015-1020. PMID: 26689853, DOI: 10.1111/ajt.13561.Peer-Reviewed Original ResearchConceptsGlomerular fibrin thrombiControl groupProtocol biopsiesDeceased donorsFibrin thrombiDeceased donor kidney transplantationDelayed graft functionDonor kidney transplantationSevere interstitial fibrosisGraft functionPostreperfusion biopsiesGraft survivalKidney transplantationSerum creatinineTubular atrophyStudy cohortGlomerular thrombiHistologic outcomesInterstitial fibrosisPreimplantation biopsyRapid resolutionBiopsyThrombusSafe practiceTransplantation