Featured Publications
Outcomes of Simultaneous Liver‐Kidney Transplantation Using Kidneys of Deceased Donors With Acute Kidney Injury
Batra RK, Ariyamuthu VK, MacConmara MP, Gupta G, Gungor AB, Tanriover B. Outcomes of Simultaneous Liver‐Kidney Transplantation Using Kidneys of Deceased Donors With Acute Kidney Injury. Liver Transplantation 2022, 28: 983-997. PMID: 35006615, DOI: 10.1002/lt.26406.Peer-Reviewed Original ResearchConceptsSimultaneous liver-kidney transplantationDeath-censored graft failureAcute kidney injuryLiver-kidney transplantationDeceased donorsKidney injuryGraft failureSCr levelsMultivariable Cox proportional hazards modelsTerminal serum creatinine levelTransplantation Network registry dataCox proportional hazards modelShorter cold ischemia timeCause graft failureGood organ qualitySerum creatinine levelsCold ischemia timeInternational consensus guidelinesProportional hazards modelLiver transplantCreatinine levelsPrimary outcomeStudy cohortIschemia timeKidney diseaseMachine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study.
Iseke S, Zeevi T, Kucukkaya AS, Raju R, Gross M, Haider SP, Petukhova-Greenstein A, Kuhn TN, Lin M, Nowak M, Cooper K, Thomas E, Weber MA, Madoff DC, Staib L, Batra R, Chapiro J. Machine Learning Models for Prediction of Posttreatment Recurrence in Early-Stage Hepatocellular Carcinoma Using Pretreatment Clinical and MRI Features: A Proof-of-Concept Study. American Journal Of Roentgenology 2022, 220: 245-255. PMID: 35975886, PMCID: PMC10015590, DOI: 10.2214/ajr.22.28077.Peer-Reviewed Original ResearchConceptsEarly-stage hepatocellular carcinomaLiver transplantHepatocellular carcinomaImaging featuresPosttreatment recurrenceOrgan allocationMean AUCLiver transplant eligibilityPretreatment clinical characteristicsPretreatment MRI examinationsKaplan-Meier analysisKaplan-Meier curvesClinical characteristicsImaging surveillanceTherapy allocationTransplant eligibilityUnderwent treatmentClinical parametersRetrospective studyUnpredictable complicationMRI dataConcept studyPoor survivalClinical impactPretreatment MRIDeep learning–assisted differentiation of pathologically proven atypical and typical hepatocellular carcinoma (HCC) versus non-HCC on contrast-enhanced MRI of the liver
Oestmann PM, Wang CJ, Savic LJ, Hamm CA, Stark S, Schobert I, Gebauer B, Schlachter T, Lin M, Weinreb JC, Batra R, Mulligan D, Zhang X, Duncan JS, Chapiro J. Deep learning–assisted differentiation of pathologically proven atypical and typical hepatocellular carcinoma (HCC) versus non-HCC on contrast-enhanced MRI of the liver. European Radiology 2021, 31: 4981-4990. PMID: 33409782, PMCID: PMC8222094, DOI: 10.1007/s00330-020-07559-1.Peer-Reviewed Original ResearchConceptsNon-HCC lesionsHepatocellular carcinomaHCC lesionsAtypical imagingGrading systemLI-RADS criteriaAtypical imaging featuresPrimary liver cancerTypical hepatocellular carcinomaAtypical hepatocellular carcinomaContrast-enhanced MRISensitivity/specificityLiver transplantMethodsThis IRBRetrospective studyLiver malignanciesImaging featuresLiver cancerAtypical featuresConclusionThis studyLesionsMRIClinical applicationCarcinomaImage-based diagnosisLiver Transplantation in the Time of COVID19: Barriers and Ethical Considerations for Management and Next Steps
Jaffe A, Schilsky ML, Deshpande R, Batra R. Liver Transplantation in the Time of COVID19: Barriers and Ethical Considerations for Management and Next Steps. Hepatology Communications 2020, 4: 1242-1256. PMID: 32838103, PMCID: PMC7361607, DOI: 10.1002/hep4.1568.Peer-Reviewed Original ResearchEnd-stage liver diseaseLiver transplantLiver transplantationLiver diseaseVirus severe acute respiratory syndrome coronavirus 2Severe acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Critical care bedsLife-saving procedureHealth care systemCorona Virus DiseasePosttransplant recipientsCoronavirus 2Transplant programsTumor controlBlood productsCOVID19 infectionCare bedsPatientsStaff contactTransplantCare systemDiseaseUtility of Liver Transplantation Within the Bounds of Non-futility
Batra R. Utility of Liver Transplantation Within the Bounds of Non-futility. Current Transplantation Reports 2020, 7: 187-193. DOI: 10.1007/s40472-020-00288-w.Peer-Reviewed Original Research
2019
Ethical Implications in Donor and Recipient Utilization for Liver Transplant
Batra R. Ethical Implications in Donor and Recipient Utilization for Liver Transplant. Current Transplantation Reports 2019, 6: 322-327. DOI: 10.1007/s40472-019-00252-3.Peer-Reviewed Original ResearchOrgan donationPhysician-patient relationshipEthical approachEthical principlesEthical dilemmasEthical issuesEthical implicationsMoral complexityMoral behaviorMoral codeHippocratic OathEgalitarian principlesUnique blendSurgical barriersTransplant communityMedical advancementsDeceased donor liversFair allocationPracticeEthicsActsPrinciplesOathDonationLiver transplant