2016
Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review
Angarita GA, Emadi N, Hodges S, Morgan PT. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review. Addiction Science & Clinical Practice 2016, 11: 9. PMID: 27117064, PMCID: PMC4845302, DOI: 10.1186/s13722-016-0056-7.Peer-Reviewed Original ResearchModafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence
Morgan PT, Angarita GA, Canavan S, Pittman B, Oberleitner L, Malison RT, Mohsenin V, Hodges S, Easton C, McKee S, Bessette A, Forselius E. Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence. Drug And Alcohol Dependence 2016, 160: 49-56. PMID: 26777774, PMCID: PMC4767553, DOI: 10.1016/j.drugalcdep.2015.12.004.Peer-Reviewed Original ResearchConceptsUrine toxicology screenModafinil treatmentSlow-wave sleepClinical outcomesOutpatient treatmentToxicology screenUrine screensInpatient settingInpatient treatmentSleep timeCocaine dependencePrimary clinical outcomeWeekly cognitive behavioral therapyCocaine usersImproved clinical outcomesPolysomnographic sleep recordingsChronic cocaine useChronic cocaine usersHigh rateCognitive behavioral therapyCocaine-dependent participantsSleep architectureOutpatient phaseEffective treatmentDays abstinent
2014
Correlates of polysomnographic sleep changes in cocaine dependence: Self-administration and clinical outcomes
Angarita GA, Canavan SV, Forselius E, Bessette A, Morgan PT. Correlates of polysomnographic sleep changes in cocaine dependence: Self-administration and clinical outcomes. Drug And Alcohol Dependence 2014, 143: 173-180. PMID: 25124303, PMCID: PMC4207081, DOI: 10.1016/j.drugalcdep.2014.07.025.Peer-Reviewed Original ResearchConceptsClinical outcomesWithdrawal symptomsNegative urineAmount of cocaineCocaine dependenceInpatient stayDays abstinentRapid eye movement (REM) sleepWeekly cognitive behavioral therapyCocaine self-administration studiesRandomized clinical trialsAbnormal sleep architectureEye movement sleepCocaine self-administration sessionsTotal sleep timeSlow-wave sleepChronic cocaine useSelf-administration sessionsSelf-administration studiesCognitive behavioral therapyRelevance of sleepPlacebo armSelf-reported useMovement sleepOutpatient treatment
2010
Normalizing Effects of Modafinil on Sleep in Chronic Cocaine Users
Morgan PT, Pace-Schott E, Pittman B, Stickgold R, Malison RT. Normalizing Effects of Modafinil on Sleep in Chronic Cocaine Users. American Journal Of Psychiatry 2010, 167: 331-340. PMID: 20080983, PMCID: PMC5857958, DOI: 10.1176/appi.ajp.2009.09050613.Peer-Reviewed Original ResearchMeSH KeywordsAdultBenzhydryl CompoundsCentral Nervous System StimulantsCocaineCocaine-Related DisordersDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleHumansMaleMiddle AgedModafinilPolysomnographySleep Wake DisordersSubstance Abuse Treatment CentersSubstance Withdrawal SyndromeWakefulnessConceptsMultiple sleep latency testSlow-wave sleep timeSleep latency testEffects of modafinilTotal sleep timeSleep latencyCocaine-dependent participantsSleep timeChronic cocaine usersDaytime sleepinessLatency testCocaine usersShorter REM sleep latencyDaytime sleep latencyLonger total sleep timeREM sleep latencySubjective daytime sleepinessSleep architecture variablesPolysomnographic sleep recordingsSleep architectureNocturnal sleepHealthy comparison participantsAbstinent cocaine usersDay 1Day 2