2020
Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT.
Tetrault JM, Holt SR, Cavallo DA, O'Connor PG, Gordon MA, Corvino JK, Nich C, Carroll KM. Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT. Journal Of Addiction Medicine 2020, 14: e303-e309. PMID: 32371660, DOI: 10.1097/adm.0000000000000663.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismCognitive Behavioral TherapyCrisis InterventionFeasibility StudiesHumansMass ScreeningPrimary Health CareReferral and ConsultationSubstance-Related DisordersConceptsSubstance use disordersComputerized cognitive behavioral therapySubstance useCognitive behavioral therapySelf-reported substance useUse disordersTechnology-based treatmentsPrimary care settingSubstance use outcomesIntegrated addictions treatmentTechnology-based interventionsBehavioral therapyPrimary care practicesOverall positive outcomeSUD interventionsBrief interventionUnhealthy alcohol useDays abstinentPositive outcomesUse outcomesCare settingsAlcohol useStandard careAddiction treatmentTreatment settings
2018
The Internist’s Challenge: Addressing Our Patients’ Unhealthy Substance Use
Samet JH, O'Connor PG, Stein MD. The Internist’s Challenge: Addressing Our Patients’ Unhealthy Substance Use. Medical Clinics Of North America 2018, 102: xvii-xviii. PMID: 29933831, DOI: 10.1016/j.mcna.2018.04.001.Peer-Reviewed Original Research
2016
Cognitive Behavioral Therapy Improves Treatment Outcomes for Prescription Opioid Users in Primary Care Buprenorphine Treatment
Moore BA, Fiellin DA, Cutter CJ, Buono FD, Barry DT, Fiellin LE, O'Connor PG, Schottenfeld RS. Cognitive Behavioral Therapy Improves Treatment Outcomes for Prescription Opioid Users in Primary Care Buprenorphine Treatment. Journal Of Substance Use And Addiction Treatment 2016, 71: 54-57. PMID: 27776678, PMCID: PMC5119533, DOI: 10.1016/j.jsat.2016.08.016.Peer-Reviewed Original ResearchConceptsOpioid-using patientsCognitive behavioral therapyUse patientsPhysician managementOpioid useTreatment outcomesBuprenorphine/naloxone treatmentHeroin use disorder patientsSelf-reported opioid useBehavioral therapyOpioid use groupPrevious drug treatmentUrine toxicology analysisEffects of CBTInjection drug useBaseline demographic differencesPrescription opioid usersBuprenorphine treatmentNaloxone treatmentOpioid abstinencePrescription opioidsOpioid usersOpioid categoryTreatment responseDrug treatment
2014
Addiction Medicine: The Birth of a New Discipline
O’Connor P, Sokol RJ, D’Onofrio G. Addiction Medicine: The Birth of a New Discipline. JAMA Internal Medicine 2014, 174: 1717-1718. PMID: 25201642, DOI: 10.1001/jamainternmed.2014.4211.Peer-Reviewed Original Research
2013
Managing Substance Dependence as a Chronic Disease: Is the Glass Half Full or Half Empty?
O’Connor P. Managing Substance Dependence as a Chronic Disease: Is the Glass Half Full or Half Empty? JAMA 2013, 310: 1132-1134. PMID: 24045739, DOI: 10.1001/jama.2013.277610.Peer-Reviewed Original Research
2012
Developing and Implementing a Multispecialty Graduate Medical Education Curriculum on Screening, Brief Intervention, and Referral to Treatment (SBIRT)
Tetrault JM, Green ML, Martino S, Thung SF, Degutis LC, Ryan SA, Martel S, Pantalon MV, Bernstein SL, O'Connor P, Fiellin DA, D'Onofrio G. Developing and Implementing a Multispecialty Graduate Medical Education Curriculum on Screening, Brief Intervention, and Referral to Treatment (SBIRT). Substance Abuse 2012, 33: 168-181. PMID: 22489589, DOI: 10.1080/08897077.2011.640220.Peer-Reviewed Original ResearchConceptsBrief interventionInternal medicineEmergency medicineMean satisfaction scoreMultiple residency programsStandardized patient sessionSBIRT curriculumClinical practicePediatric programsSBIRTSatisfaction scoresClinical encountersPatient sessionsPediatric residentsProject facultyTraining Web siteStandardized patientsReferralGynecologyObstetricsNumber of residentsResidency programsSatisfaction surveyGraduate medical education curriculumFaculty supervision
2008
Substance Abuse and Withdrawal in the Critical Care Setting
Tetrault JM, O'Connor PG. Substance Abuse and Withdrawal in the Critical Care Setting. Critical Care Clinics 2008, 24: 767-788. PMID: 18929942, DOI: 10.1016/j.ccc.2008.05.005.Commentaries, Editorials and LettersMeSH KeywordsAlcohol Withdrawal SeizuresAnalgesics, OpioidBenzodiazepinesCritical CareHumansSubstance Withdrawal SyndromeSubstance-Related DisordersUnited StatesConceptsCritical care settingWithdrawal syndromeCare settingsOverall treatment protocolSubstance useSubstance withdrawal syndromeSymptom-triggered approachCritical care teamTapering doseAcute presentationResuscitative measuresCare teamTreatment protocolHigh indexSubstance intoxicationSubstance abuseAbused drugsSyndromeTreatmentWithdrawalEpidemiologySettingSuspicionDoseIntoxication
2007
Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction.
Martell BA, O'Connor PG, Kerns RD, Becker WC, Morales KH, Kosten TR, Fiellin DA. Systematic review: opioid treatment for chronic back pain: prevalence, efficacy, and association with addiction. Annals Of Internal Medicine 2007, 146: 116-27. PMID: 17227935, DOI: 10.7326/0003-4819-146-2-200701160-00006.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidChronic DiseaseClinical Trials as TopicDrug PrescriptionsHumansLow Back PainPrevalenceSubstance-Related DisordersUnited StatesConceptsChronic back painSubstance use disordersEfficacy of opioidsBack painMedication-taking behaviorUse disordersOpioid treatmentOpioid medicationsStudy qualityShort-term pain reliefCurrent substance use disorderCochrane Central RegisterLifetime substance use disorderControlled Clinical TrialsLong-term efficacyPoor study qualityEnglish-language studiesTransdermal opioidsOpioid prescribingPain reliefCentral RegisterDifferent opioidsReduced painClinical trialsNonsignificant reduction
2003
Management of Drug and Alcohol Withdrawal
Kosten TR, O'Connor PG. Management of Drug and Alcohol Withdrawal. New England Journal Of Medicine 2003, 348: 1786-1795. PMID: 12724485, DOI: 10.1056/nejmra020617.Peer-Reviewed Original ResearchConnecticut statewide addiction medicine/psychiatry grand rounds.
Kraus ML, O'Connor P, Babor TF, Brunell RJ, Fiellin DA, Holmboe E, Kirk TA, Leone P. Connecticut statewide addiction medicine/psychiatry grand rounds. Connecticut Medicine 2003, 67: 357-9. PMID: 12956044.Peer-Reviewed Educational Materials
2002
The physician's role in caring for patients with substance use disorders: Implications for medical education and training
Fiellin DA, Butler R, D'Onofrio G, Brown RL, O'Connor PG. The physician's role in caring for patients with substance use disorders: Implications for medical education and training. Substance Abuse 2002, 23: 207-222. PMID: 23580996, DOI: 10.1080/08897070209511516.Peer-Reviewed Educational MaterialsUse of Alcohol, Illicit Drugs, and Tobacco among Characters on Prime–Time Television
Long JA, O'Connor PG, Gerbner G, Concato J. Use of Alcohol, Illicit Drugs, and Tobacco among Characters on Prime–Time Television. Substance Abuse 2002, 23: 95-103. PMID: 12444354, DOI: 10.1080/08897070209511479.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingFemaleHumansIllicit DrugsMalePrevalenceSubstance-Related DisordersTelevisionTobacco Use DisorderVisual PerceptionSubstance Abuse
O'Connor PG, Samet JH. Substance Abuse. Journal Of General Internal Medicine 2002, 17: 398-399. PMID: 12047739, PMCID: PMC1495043, DOI: 10.1046/j.1525-1497.2002.20212.x.Peer-Reviewed Original Research
2001
A Call for Papers
O'Connor P, Samet J. A Call for Papers. Journal Of General Internal Medicine 2001, 16: 70-71. PMID: 11251754, PMCID: PMC1495159, DOI: 10.1111/j.1525-1497.2001.01107.x.Peer-Reviewed Original Research
2000
HIV post-exposure therapy for drug users in treatment
O'Connor P. HIV post-exposure therapy for drug users in treatment. Journal Of Substance Use And Addiction Treatment 2000, 18: 17-21. PMID: 10636602, DOI: 10.1016/s0740-5472(99)00015-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsCross-Sectional StudiesHIV InfectionsHumansSubstance-Related DisordersConceptsPost-exposure therapyMethadone maintenance programDrug usersOccupational exposurePrimary care providersCross-sectional evaluationHIV prevention messagesGroups of providersNonoccupational exposureProvider staffNeedle stickDrug treatmentCare providersFocus groupsPrevention messagesTreatment programProgram providersTreatment staffFurther studiesHIVFuture riskTherapyTreatmentCase vignettesExposure
1998
Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment
Durante AJ, Selwyn PA, O'Connor PG. Risk factors for and knowledge of Mycobacterium tuberculosis infection among drug users in substance abuse treatment. Addiction 1998, 93: 1393-1401. PMID: 9926545, DOI: 10.1046/j.1360-0443.1998.939139310.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAttitude to HealthAwarenessConnecticutFemaleHumansIncidenceMaleMass ScreeningMiddle AgedPrevalenceRisk FactorsSubstance-Related DisordersTuberculosisConceptsMycobacterium tuberculosis infectionTB knowledgeTuberculosis infectionDrug treatment programsRisk factorsDrug usersPositive TB skin testsTreatment programTB skin testTB risk factorsM. tuberculosis infectionTuberculin skin testingLow TB incidenceNeedles/syringesNon-white raceIncidence of infectionDrug treatment facilitiesPrevalence of infectionSubstance abuse treatmentSubsample of clientsPreventive therapyTB controlSkin testingTB incidenceInfected subjects
1997
PHYSICIAN IMPAIRMENT BY SUBSTANCE ABUSE
O'Connor P, Spickard A. PHYSICIAN IMPAIRMENT BY SUBSTANCE ABUSE. Medical Clinics Of North America 1997, 81: 1037-1052. PMID: 9222267, DOI: 10.1016/s0025-7125(05)70562-9.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismDiagnosis, DifferentialHumansInternship and ResidencyPhysician ImpairmentRecurrenceRisk FactorsStudents, MedicalSubstance-Related DisordersConceptsSubstance abusePhysician impairmentIllicit drug abusePrevalence of alcoholSubstance abuse problemsImpaired physiciansGeneral populationTreatment approachesPrescription drugsPhysiciansDrug abuseAbuse problemsImpairmentMedicolegal standpointCare organizationsPatientsImproved attentionAbuseHospitalPrevalencePHARMACOTHERAPY FOR OPIOID AND COCAINE ABUSE
Warner E, Kosten T, O'Connor P. PHARMACOTHERAPY FOR OPIOID AND COCAINE ABUSE. Medical Clinics Of North America 1997, 81: 909-925. PMID: 9222260, DOI: 10.1016/s0025-7125(05)70555-1.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsCocaineDopamine AgonistsFemaleHumansMethadoneNarcotic AntagonistsNarcoticsPregnancyPregnancy ComplicationsSubstance-Related DisordersSustained-release methylphenidate for cognitive impairment in HIV-1- infected drug abusers: a pilot study
van Dyck CH, McMahon TJ, Rosen MI, O'Malley SS, O'Connor PG, Lin CH, Pearsall HR, Woods SW, Kosten TR. Sustained-release methylphenidate for cognitive impairment in HIV-1- infected drug abusers: a pilot study. Journal Of Neuropsychiatry 1997, 9: 29-36. PMID: 9017526, DOI: 10.1176/jnp.9.1.29.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCentral Nervous System StimulantsCognition DisordersDelayed-Action PreparationsDouble-Blind MethodFemaleHIV InfectionsHIV-1HumansLearningMaleMemoryMethylphenidateMiddle AgedNeuropsychological TestsOpioid-Related DisordersPilot ProjectsPsychomotor PerformanceSubstance-Related DisordersConceptsSustained-release methylphenidateCognitive impairmentDouble-blind placebo-controlled crossover trialPlacebo-controlled crossover trialComposite neuropsychological measuresImpaired neuropsychological test performanceClinical improvementPlacebo treatmentCrossover trialMethadone patientsNeuropsychological test performancePlacebo performancePsychostimulant drugsDrug abusersPatientsStudy designPilot studySubstance abusersImpairmentNeuropsychological measuresMethylphenidateMore improvementAbusersTreatmentTest performance
1994
SPECT regional cerebral blood flow alterations in naltrexone-precipitated withdrawal from buprenorphine
van Dyck C, Rosen M, Thomas H, McMahon T, Wallace E, O'Connor P, Sullivan M, Krystal J, Hoffer P, Woods S, Kosten T. SPECT regional cerebral blood flow alterations in naltrexone-precipitated withdrawal from buprenorphine. Psychiatry Research 1994, 55: 181-191. PMID: 7701033, DOI: 10.1016/0925-4927(94)90013-2.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowRegional cerebral blood flow alterationsCerebral blood flow alterationsHexamethyl propylene amine oximeOpiate-induced analgesiaBlood flow alterationsSeverity of withdrawalCerebral blood flowOpiate-dependent patientsAnterior cingulate regionsAnterior cingulate cortexSingle photon emissionPlacebo administrationAmine oximeOpiate withdrawalRCBF ratiosWithdrawal severityBlood flowCingulate cortexCingulate regionsSignificant negative correlationBuprenorphineNaltrexonePlaceboPatients