2015
Signaling pathways in biliary epithelial cells
Leite M, Guerra M, Andrade V, Nathanson M. Signaling pathways in biliary epithelial cells. 2015, 15-33. DOI: 10.1002/9781118663387.ch2.Peer-Reviewed Original ResearchBiliary epithelial cellsEpithelial cellsFormation of bileSurface membrane receptorsBiliary treeDuctal bileIntracellular signal transduction pathwaysCanalicular bileGrowth factorCholangiocytesBileCell functionPeptide hormonesBile saltsDetoxification of xenobioticsMembrane receptorsSignal transduction pathwaysTransduction pathways
2009
Signaling Pathways in Biliary Epithelial Cells
Leite M, Andrade V, Nathanson M. Signaling Pathways in Biliary Epithelial Cells. 2009, 25-39. DOI: 10.1007/978-3-642-00150-5_2.Peer-Reviewed Original ResearchBiliary epithelial cellsEpithelial cellsFormation of bileSurface membrane receptorsBiliary treeDuctal bileIntracellular signal transduction pathwaysCanalicular bileGrowth factorCholangiocytesBileCell functionPeptide hormonesBile saltsDetoxification of xenobioticsMembrane receptorsSignal transduction pathwaysTransduction pathways
2001
Stimulation of ATP secretion in the liver by therapeutic bile acids
NATHANSON M, BURGSTAHLER A, MASYUK A, LaRUSSO N. Stimulation of ATP secretion in the liver by therapeutic bile acids. Biochemical Journal 2001, 358: 1-5. DOI: 10.1042/bj3580001.Peer-Reviewed Original ResearchBile duct epitheliumUrsodeoxycholic acidBile acidsSecretory disordersATP receptorsPerfusion of ATPBile duct segmentsEndogenous ATPTherapeutic bile acidsSecretion of ATPNumber of disordersMechanism of actionBile flowPharmacological activationPharmacological meansTherapeutic benefitElectrolyte secretionDelivery of ATPATP secretionCystic fibrosisOnly agentATP releaseBileCytosolic Ca2Liver