2024
Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study
Powierza C, Doyle M, Wasden K, Intihar T, Korwin A, Honiden S, Knauert M. Early goal enteral nutrition associated with decreased in-hospital death in mechanically ventilated critically ill adults: a retrospective cohort study. BMJ Open Respiratory Research 2024, 11: e001962. PMID: 38749534, PMCID: PMC11097881, DOI: 10.1136/bmjresp-2023-001962.Peer-Reviewed Original ResearchConceptsEarly enteral nutritionIn-hospital deathCritically ill adultsRetrospective cohort studyDays of intubationEnteral nutritionIll adultsAdult patientsCohort studyAssociated with decreased in-hospital deathsMechanically ventilated critically ill adultsGoal enteral nutritionIncreased hospital dischargeInitiation of ENCritically ill adult patientsMechanically ventilated adult patientsIncidence of in-hospital deathMedical intensive care unitAssociated with significant improvementsIll adult patientsDose of ENIntensive care unitClinical outcomesImprove mortalityPrimary outcome
2019
Pilot study: an intensive care unit sleep promotion protocol
Knauert MP, Pisani M, Redeker N, Murphy T, Araujo K, Jeon S, Yaggi H. Pilot study: an intensive care unit sleep promotion protocol. BMJ Open Respiratory Research 2019, 6: e000411. PMID: 31258916, PMCID: PMC6561389, DOI: 10.1136/bmjresp-2019-000411.Peer-Reviewed Original ResearchConceptsPromotion protocolProtocol armUsual careSleep protocolICU sleepProtocol patientsIll patientsPrimary outcomeSleep disruptionBedside careRoom entryPatientsRoom activitiesSleep opportunityCareLength of timeProtocol effectMean ARoom disturbancesGeneralised linear modelArmTime blocksEquivalent levelsRoom entranceActivity
2017
Sleep Disturbance after Hospitalization and Critical Illness: A Systematic Review
Altman MT, Knauert MP, Pisani MA. Sleep Disturbance after Hospitalization and Critical Illness: A Systematic Review. Annals Of The American Thoracic Society 2017, 14: 1457-1468. PMID: 28644698, PMCID: PMC5711402, DOI: 10.1513/annalsats.201702-148sr.BooksConceptsCritical illnessHospital dischargeSleep disturbancesRisk factorsSystematic reviewIntensive care unit admissionCare unit admissionIll adult patientsTime pointsCritical illness survivorsObjective sleep parametersQuestionnaire studyUnit admissionAdult patientsHospital factorsIll patientsPrimary outcomePrehospital factorsImpaired qualityObjective measurement toolsPsychological comorbiditiesAbnormal sleepMultiple time pointsPolysomnography studiesPoor sleep