2024
Sex and HIV Differences in Preserved Ratio Impaired Spirometry (PRISm) Among Ugandans Postpneumonia
Abelman R, Fitzpatrick J, Byanova K, Zawedde J, Sanyu I, Byanyima P, Musisi E, Hsieh J, Zhang M, Branchini J, Sessolo A, Hunt P, Lalitha R, Davis J, Crothers K, Worodria W, Huang L. Sex and HIV Differences in Preserved Ratio Impaired Spirometry (PRISm) Among Ugandans Postpneumonia. Open Forum Infectious Diseases 2024, 11: ofae033. PMID: 38456193, PMCID: PMC10919919, DOI: 10.1093/ofid/ofae033.Peer-Reviewed Original ResearchPreserved ratio impaired spirometryAssociated with increased oddsFemale sexAssociated with lower oddsBiomass fuel exposureAssociated with increased mortalityBaseline participantsLower oddsDecreased oddsHIV statusPost-pneumoniaIncreased oddsGeneral populationImpaired spirometryLung function abnormalitiesFuel exposureIncreased riskEffects of sexTB statusHIVLow FEV1Normal spirometryParticipantsHIV effectsSpirometry
2023
Sex modifies the risk of HIV-associated obstructive lung disease in Ugandans postpneumonia
Abelman R, Fitzpatrick J, Zawedde J, Sanyu I, Byanyima P, Kaswabuli S, Musisi E, Hsieh J, Gardner K, Zhang M, Byanova K, Sessolo A, Hunt P, Lalitha R, Davis J, Crothers K, Worodria W, Huang L. Sex modifies the risk of HIV-associated obstructive lung disease in Ugandans postpneumonia. AIDS 2023, 37: 1683-1692. PMID: 37352494, PMCID: PMC10527596, DOI: 10.1097/qad.0000000000003626.Peer-Reviewed Original ResearchConceptsObstructive lung diseaseLung diseaseLung functionAbnormal lung functionMultivariable regression modelsWarrants further studyCommon comorbiditiesExpiratory volumeSpirometric abnormalitiesSmoking statusSpirometric testingTB statusVital capacitySex modifiesStratified analysisHIVWomenDiseaseComorbiditiesMenSexFurther studiesGreater degreeRiskTuberculosis