2013
GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons
Liang L, Li Y, Potter CJ, Yizhar O, Deisseroth K, Tsien RW, Luo L. GABAergic Projection Neurons Route Selective Olfactory Inputs to Specific Higher-Order Neurons. Neuron 2013, 79: 917-931. PMID: 24012005, PMCID: PMC3838762, DOI: 10.1016/j.neuron.2013.06.014.Peer-Reviewed Original ResearchConceptsLateral horn neuronsInhibitory projection neuronsInnate olfactory behaviorsInhibitory tonePresynaptic inhibitionDrosophila olfactory systemHigher-order neuronsProjection neuronsAxon terminalsAntennal lobe glomeruliLateral hornConnection specificityDetectable suppressionOlfactory inputOdor responsesNeuronsOlfactory informationOlfactory systemHigher centersParallel inhibitionDifferential effectsDownstream circuitsInhibition motifCircuit motifsInhibitionLinking Cell Fate, Trajectory Choice, and Target Selection: Genetic Analysis of Sema-2b in Olfactory Axon Targeting
Joo WJ, Sweeney LB, Liang L, Luo L. Linking Cell Fate, Trajectory Choice, and Target Selection: Genetic Analysis of Sema-2b in Olfactory Axon Targeting. Neuron 2013, 78: 673-686. PMID: 23719164, PMCID: PMC3727417, DOI: 10.1016/j.neuron.2013.03.022.Peer-Reviewed Original ResearchConceptsNeural circuit assemblySema-2bCell fateSpecific cell fatesCircuit assemblyORN classesTemporal regulationTrajectory choiceSema-2aAxon bundle formationGenetic analysisAxon targetingAxon-axon interactionsNeuron developmentCellular mechanismsGuidance moleculesORN axonsSemaphorinsSynaptic targetsFateAssemblyTarget selectionPostsynaptic target neuronsAxonal trajectoriesRegulation
2010
The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis
Potter CJ, Tasic B, Russler EV, Liang L, Luo L. The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis. Cell 2010, 141: 536-548. PMID: 20434990, PMCID: PMC2883883, DOI: 10.1016/j.cell.2010.02.025.Peer-Reviewed Original ResearchConceptsMARCM analysisQa gene clusterCell division patternsBinary expression systemTransgene expression patternsTransgene expressionGAL4 systemGene functionMosaic analysisGene clusterRegulatory genesMammalian cellsCell divisionDivision patternsLow basal expressionLineage tracingExpression systemExpression patternsNeuronal lineageOlfactory attractionCell growthBasal expressionDrosophilaRepressionExpression