2024
Prognostic Understanding, Goals of Care, and Quality of Life in Hospitalized Patients with Leukemia or Multiple Myeloma
Shimer S, Allen O, Yang C, Canavan M, Westvold S, Kim N, Morillo J, Parker T, Wallace N, Smith C, Adelson K. Prognostic Understanding, Goals of Care, and Quality of Life in Hospitalized Patients with Leukemia or Multiple Myeloma. Journal Of Palliative Medicine 2024, 27: 879-887. PMID: 38990245, DOI: 10.1089/jpm.2023.0530.Peer-Reviewed Original ResearchGoals of carePrognostic awarenessQuality of lifeIllness understandingPrognostic understandingMultiple myelomaHematologic malignanciesAcute leukemiaFaith-based responseInformed treatment choicesChi-square testCohort of patientsLikelihood ratio chi-square testMount Sinai HospitalTreatment goalsMM cohortSinai HospitalCarePatient populationTreatment choiceHospitalized patientsHematologistsAssess discordanceLeukemiaPatientsSystemic anti-cancer therapy and cost at end of life: A SEER Medicare analysis.
Adelson K, Cheng L, Huang Y, Niu J, Zhao H, Nortje N, Xiang J, Giordano S, Canavan M. Systemic anti-cancer therapy and cost at end of life: A SEER Medicare analysis. Journal Of Clinical Oncology 2024, 42: 11092-11092. DOI: 10.1200/jco.2024.42.16_suppl.11092.Peer-Reviewed Original ResearchSystemic anticancer therapyCombined chemo-immunotherapyLiquid tumorsSolid tumorsDay of deathEmergency departmentRates of systemic therapySystemic anti-cancer therapySEER-Medicare databaseAnti-cancer therapyChemo-immunotherapyLT patientsSystemic therapyCI patientsSEER-MedicareST patientsIdentified patientsCost of drugsAssociated with higher costsEnd of lifeAnticancer therapyImmunotherapyChemotherapyPatientsTherapy
2022
Systemic Anticancer Therapy at the End of Life—Changes in Usage Pattern in the Immunotherapy Era
Canavan ME, Wang X, Ascha MS, Miksad RA, Calip GS, Gross CP, Adelson KB. Systemic Anticancer Therapy at the End of Life—Changes in Usage Pattern in the Immunotherapy Era. JAMA Oncology 2022, 8: 1847-1849. PMID: 36264566, PMCID: PMC9585458, DOI: 10.1001/jamaoncol.2022.4666.Peer-Reviewed Original Research
2021
A Phase II Study Evaluating Orteronel, an Inhibitor of Androgen Biosynthesis, in Patients With Androgen Receptor (AR)-Expressing Metastatic Breast Cancer (MBC)
Yardley DA, Young RR, Adelson KB, Silber AL, Najera JE, Daniel DB, Peacock N, Finney L, Hoekstra SJ, Shastry M, Hainsworth JD, Burris HA. A Phase II Study Evaluating Orteronel, an Inhibitor of Androgen Biosynthesis, in Patients With Androgen Receptor (AR)-Expressing Metastatic Breast Cancer (MBC). Clinical Breast Cancer 2021, 22: 269-278. PMID: 34824002, DOI: 10.1016/j.clbc.2021.10.011.Peer-Reviewed Original ResearchConceptsMetastatic breast cancerCohort 2Cohort 1Breast cancerAndrogen biosynthesisAmylase/lipaseLimited clinical activityPrior chemotherapy regimenPrior chemotherapy regimensMedian treatment durationNausea/vomitingChemotherapy regimenChemotherapy regimensPrimary endpointObjective responseOverall survivalFemale patientsAndrogen receptorClinical activityGrade 3Targetable pathwaysPatientsTherapeutic targetAR modulationTreatment durationDifferences by race in systemic oncologic end-of-life (EOL) care among patients with cancer.
Adelson K, Wang X, Ascha M, Miksad R, Showalter T, Calip G, Gross C, Canavan M. Differences by race in systemic oncologic end-of-life (EOL) care among patients with cancer. Journal Of Clinical Oncology 2021, 39: 137-137. DOI: 10.1200/jco.2020.39.28_suppl.137.Peer-Reviewed Original ResearchBlack patientsWhite patientsAggressive EOL careRetrospective cohort studyPractice-level factorsPractice-level characteristicsRacial differencesDe-identified databaseLogistic regression modelsAnti-cancer therapyElectronic health recordsImmunotherapy eraCohort studyICI useOncologic treatmentPayer cohortHigh patientEOL careAdjusted ratesOutcome measuresEOL treatmentMedicaid coveragePatientsPhysician ratioRoutine practiceImpact of a Dedicated Cancer Urgent Care Center on Acute Care Utilization
Rothberg BE, Canavan ME, Mun S, Sedghi T, Carafeno T, Raucci M, Dest V, Sinanis N, Gross CP, Adelson KB. Impact of a Dedicated Cancer Urgent Care Center on Acute Care Utilization. JCO Oncology Practice 2021, 18: e129-e136. PMID: 34383579, DOI: 10.1200/op.21.00183.Peer-Reviewed Original ResearchConceptsUrgent care centersCare centerHospitalization ratesLarge tertiary academic centerAcute care useAcute care utilizationEmergency department presentationsTertiary academic centerEmergency room utilizationCancer care costsPeriod 1 yearProvider visitsActive therapyHospital admissionPrimary outcomeCare utilizationOncology patientsAcute careCare useClinic capacityPatient awarenessPhysician comfortClinical pathwayPatientsAcademic centersTelehealth in Oncology: ASCO Standards and Practice Recommendations
Zon RT, Kennedy EB, Adelson K, Blau S, Dickson N, Gill D, Laferriere N, Lopez AM, Mulvey TM, Patt D, Pickard TA, Purdom T, Royce TJ, Sumrall AL, Page RD. Telehealth in Oncology: ASCO Standards and Practice Recommendations. JCO Oncology Practice 2021, 17: 546-564. PMID: 34319760, DOI: 10.1200/op.21.00438.Peer-Reviewed Original ResearchConceptsSystematic reviewPractice recommendationsExpert panelClinical practice guidelinesMultidisciplinary cancer conferencesAdvanced practice providersAllied health professionalsSpecialty settingsCancer ConferencePractice guidelinesPractice providersHealth professionalsCare deliveryEvidence baseOncologySystematic searchTelehealthPatientsPrimary studiesFinal manuscriptReview
2020
Conducting Goals-of-Care Discussions Takes Less Time Than Imagined.
Pintova S, Leibrandt R, Smith CB, Adelson KB, Gonsky J, Egorova N, Franco R, Bickell NA. Conducting Goals-of-Care Discussions Takes Less Time Than Imagined. JCO Oncology Practice 2020, 16: e1499-e1506. PMID: 32749930, DOI: 10.1200/jop.19.00743.Peer-Reviewed Original ResearchConceptsGOC discussionsCare discussionsAdvanced solid tumor cancersDifferent hospital typesLength of encounterSolid tumor cancersTotal encounter timePatient ageAdvanced cancerHospital typeRural hospitalsMedicare coveragePatientsCancer progressionOncologistsMultivariate modelEncounter timeVisitsSignificant differencesCancerProgressionMinutesLess timeCommon misperceptionsPrognosisPatient and Family Caregiver Considerations When Selecting Early Breast Cancer Treatment: Implications for Clinical Pathway Development
Schulman-Green D, Cherlin E, Capasso R, Mougalian SS, Wang S, Gross CP, Bajaj PS, Eakle K, Patel S, Douglas K, Adelson K. Patient and Family Caregiver Considerations When Selecting Early Breast Cancer Treatment: Implications for Clinical Pathway Development. The Patient - Patient-Centered Outcomes Research 2020, 13: 683-697. PMID: 32508006, DOI: 10.1007/s40271-020-00426-7.Peer-Reviewed Original ResearchConceptsFamily caregiversTreatment optionsDecision regretHealth care system issuesEarly breast cancer treatmentCaregiver considerationsCancer treatment patternsInitial definitive treatmentClinical pathway developmentBreast cancer treatmentFamily caregivers' perspectivesConsideration of patientsDecision pathwaysFindings patientsDefinitive treatmentTreatment patternsSpouse/partnerBreast cancerClinical pathwayTreatment decisionsCancer statusPatientsStage ICaregiver perspectivesTreatment planNSCLC: Integrating the “Yale model shared decision-making solution” into the practice setting.
Adelson K, Herbst R, Peterson P, Ingram M, Oliver B, Agrawal T, Davies M, Rudell E. NSCLC: Integrating the “Yale model shared decision-making solution” into the practice setting. Journal Of Clinical Oncology 2020, 38: 7054-7054. DOI: 10.1200/jco.2020.38.15_suppl.7054.Peer-Reviewed Original ResearchCheckpoint inhibitor therapyReasonable treatment optionMore side effectsLung cancer patientsCancer care settingsPatient-centered careTreatment decision processNational Quality ForumInhibitor therapyPatient-centric careCancer patientsTreatment optionsTreatment choicePost-intervention interviewsPatientsSide effectsPractice settingsQuality ForumSDM skillsHealthcare decisionsCareSDM processGreater improvementCliniciansTeam membersEffects of a Communication Intervention Randomized Controlled Trial to Enable Goals-of-Care Discussions.
Bickell NA, Back AL, Adelson K, Gonsky JP, Egorova N, Pintova S, Lin JJ, Kozuch P, Bagiella E, Smith CB. Effects of a Communication Intervention Randomized Controlled Trial to Enable Goals-of-Care Discussions. JCO Oncology Practice 2020, 16: e1015-e1028. PMID: 32374710, DOI: 10.1200/op.20.00040.Peer-Reviewed Original ResearchConceptsElicit patient valuesEnd of lifeAdvanced cancerPatient valuesAggressive careGOC discussionsCare discussionsIntensive care unit admissionHigh care utilizationCare unit admissionMean hospitalizationTraining oncologistsUnit admissionUC patientsAggressive treatmentCare utilizationBlock randomizationCommunication skills trainingOncologistsPatientsCancerCommunication interventionsPrevalenceLife expectancyLast monthImpact of High-Quality Goals-of-Care Discussions on Oncologist Productivity.
Pintova S, Leibrandt R, Smith CB, Adelson KB, Gonsky JP, Egorova N, Franco R, Bickell NA. Impact of High-Quality Goals-of-Care Discussions on Oncologist Productivity. JCO Oncology Practice 2020, 16: e290-e297. PMID: 32048945, DOI: 10.1200/jop.19.00381.Peer-Reviewed Original ResearchConceptsGOC discussionsAdvanced cancerPatient populationCare discussionsPractice settingsDifferent practice settingsOncologist characteristicsStudy patientsCommunity hospitalRural hospitalsPatientsOncologistsHigh-quality goalsRural settingsSignificant differencesHospitalCancerValue unitsHoursSettingPrognosisPopulationCommunication skillsVisits
2019
Development of a time to treatment metric across an NCI designated academic health system.
Najarian M, Shaw P, Severino K, Hamrick J, Adelson K. Development of a time to treatment metric across an NCI designated academic health system. Journal Of Clinical Oncology 2019, 37: 307-307. DOI: 10.1200/jco.2019.37.27_suppl.307.Peer-Reviewed Original ResearchSmilow Cancer HospitalMedian treatmentHealth systemAdditional cancer treatmentNew patient visitsMultidisciplinary care coordinationQuality improvement interventionsAcademic health systemLarge health systemDe-identified databaseInterventional surgeryQualifying visitOverall survivalQualifying patientsDevelopment of interventionsPathology reviewCancer HospitalImportant quality metricCancer patientsPatient preferencesPatient satisfactionCare coordinationMedical recordsPatient visitsPatientsUnderstanding cancer care coordination: Opening the black box.
Canavan M, Sedghi T, Gross C, Lane S, Bogdan J, Adelson K. Understanding cancer care coordination: Opening the black box. Journal Of Clinical Oncology 2019, 37: e18310-e18310. DOI: 10.1200/jco.2019.37.15_suppl.e18310.Peer-Reviewed Original ResearchIndirect patient careCare coordinatorsPatient careAcute care utilizationCare management programSite of careDirect patient careOncology Care ModelElderly patientsMultidisciplinary careTreatment complicationsCare utilizationCancer careSymptom assessmentCare coordinationOutpatient careCare modelCare plansHigh riskAcademic centersNurses' experiencesCancer supportPatientsCareActivity timeThe impact of communication style on patient satisfaction
Trant AA, Szekely B, Mougalian SS, DiGiovanna MP, Sanft T, Hofstatter E, Silber A, Adelson KB, Chagpar A, Killelea B, Horowitz N, Lannin D, Park T, Corso M, Abraham G, Pollard-Murphy K, Sturrock T, Knill-Selby E, Western A, Servodidio C, Tasoulis MK, Healy B, Hatzis C, Pusztai L. The impact of communication style on patient satisfaction. Breast Cancer Research And Treatment 2019, 176: 349-356. PMID: 31025271, DOI: 10.1007/s10549-019-05232-w.Peer-Reviewed Original ResearchConceptsPatient satisfactionSatisfaction scoresBrief demographic formPhysical health scoresHigh patient satisfactionPatient satisfaction scoresAdvanced practice providersRoutine followPatient pairsDoctor QuestionnaireResultsIn totalHospital satisfactionBreast centerHealth SurveyPractice providersHealth scoresMethodsThis studyPatientsConcordance scoreMixed effects modelsDemographic formScoresEmployment statusPearson correlationProvidersThirty-Day Readmissions in Patients With Metastatic Cancer: Room for Improvement?
Solomon R, Egorova N, Adelson K, Smith CB, Franco R, Bickell NA. Thirty-Day Readmissions in Patients With Metastatic Cancer: Room for Improvement? JCO Oncology Practice 2019, 15: e410-e419. PMID: 30925070, DOI: 10.1200/jop.18.00500.Peer-Reviewed Original ResearchConceptsHigher readmission ratesReadmission ratesMetastatic cancerPreventable readmissionsTeaching hospitalNew York State hospital dischargesThirty-day readmissionState hospital dischargeSkilled nursing facilitiesCompeting-risks modelReadmission likelihoodAdvanced diseaseDischarge homeDischarge dispositionHospital dischargeYounger patientsReadmission reduction effortsHospice dischargeFemale sexHospital typeReadmissionNursing facilitiesPatientsHealth needsYounger age
2018
Disparities in length of goals of care conversations between oncologists and patients with advanced cancer.
Smith C, Pintova S, Adelson K, Gonsky J, Egorova N, Bickell N. Disparities in length of goals of care conversations between oncologists and patients with advanced cancer. Journal Of Clinical Oncology 2018, 36: 19-19. DOI: 10.1200/jco.2018.36.34_suppl.19.Peer-Reviewed Original ResearchNon-minority patientsProgression of diseaseMinority patientsAdvanced cancerCancer patientsHigh-quality cancer careAdvanced cancer patientsGoals of careMinority cancer patientsNon-Hispanic blacksNon-Hispanic whitesPaucity of dataGOC conversationsGOC discussionsCancer carePoor survivalCare conversationsPatientsRural hospitalsSubstandard treatmentCommunication skills trainingOncologistsCancer treatmentRisk adjustmentMixed-effects modelsSimple interventions to decrease use of chemotherapy in patients at the end of life.
Chiang A, Adelson K, Kapo J, Severino K, Lilenbaum R. Simple interventions to decrease use of chemotherapy in patients at the end of life. Journal Of Clinical Oncology 2018, 36: 181-181. DOI: 10.1200/jco.2018.36.30_suppl.181.Peer-Reviewed Original ResearchDays of lifeCourse of illnessEnd of lifeDay of deathGOC conversationsPrimary oncologistCare centerEarly palliative care referralPalliative care referralUse of chemotherapyPalliative care trainingChemotherapy utilizationCare referralPoor prognosisGOC discussionsCancer patientsUnnecessary treatmentGeneral oncologistsCare conversationsPost interventionPatientsChemotherapyMultidisciplinary teamPatient carePhysicians' skillsDoes training oncologists to have goals of care discussions affect healthcare utilization among patients with advanced cancer?
Bickell N, Adelson K, Gonsky J, Lin J, Franco R, Egorova N, Smith C. Does training oncologists to have goals of care discussions affect healthcare utilization among patients with advanced cancer? Journal Of Clinical Oncology 2018, 36: 6595-6595. DOI: 10.1200/jco.2018.36.15_suppl.6595.Peer-Reviewed Original ResearchDoes training oncologists to have goals of care discussions increase and improve the quality of GoC discussions with advanced cancer patients?
Bickell N, Adelson K, Gonsky J, Lin J, Pintova S, Franco R, Egorova N, Smith C. Does training oncologists to have goals of care discussions increase and improve the quality of GoC discussions with advanced cancer patients? Journal Of Clinical Oncology 2018, 36: 6597-6597. DOI: 10.1200/jco.2018.36.15_suppl.6597.Peer-Reviewed Original Research