2024
High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine
Ottesen T, Wickersham J, Lawrence J, Antoniak S, Zezuilin O, Polonsky M, Antonyak S, Rozanova J, Dvoriak S, Pykalo I, Filippovych M, Altice F. High rates of deferring antiretroviral treatment for patients with HIV and substance use disorders: Results from a national sample of HIV physicians in Ukraine. PLOS ONE 2024, 19: e0305086. PMID: 39028735, PMCID: PMC11259278, DOI: 10.1371/journal.pone.0305086.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy prescriptionAntiretroviral therapyCD4 countSubstance use disordersIncreased levels of stigmaNational sampleLevel of stigmaIndependent of risk groupSuboptimal antiretroviral therapyInitiate antiretroviral therapyPopulation of peopleHIV expertsHIV incidenceHIV physiciansHIV treatmentKey populationsTransgender womenAntiretroviral treatmentFeeling thermometerDrinking alcoholSex workersPhysiciansSex partnersPWHRisk groups
2021
HIV care continuum among cisgender and transgender women sex workers in Greater Kuala Lumpur, Malaysia
Ranjit YS, Gibson BA, Altice FL, Kamarulzaman A, Azwa I, Wickersham JA. HIV care continuum among cisgender and transgender women sex workers in Greater Kuala Lumpur, Malaysia. AIDS Care 2021, 35: 784-790. PMID: 34723714, PMCID: PMC9056582, DOI: 10.1080/09540121.2021.1995839.Peer-Reviewed Original ResearchConceptsTransgender women sex workersHIV care continuumAntiretroviral treatmentSex workersCare continuumWomen sex workersTransgender womenImportant key populationProportion of womenRespondent-driven sampling studyEvidence-based strategiesAntiretroviral therapyHIV careHIV prevalenceHIV epidemicHIVKey populationsWomenKuala LumpurCisgender womenCount testUnique needsSmall proportionTherapyPopulation
2017
Physician Decisions to Defer Antiretroviral Therapy in Key Populations: Implications for Reducing Human Immunodeficiency Virus Incidence and Mortality in Malaysia
Ferro EG, Culbert GJ, Wickersham JA, Marcus R, Steffen AD, Pauls HA, Westergaard RP, Lee CK, Kamarulzaman A, Altice FL. Physician Decisions to Defer Antiretroviral Therapy in Key Populations: Implications for Reducing Human Immunodeficiency Virus Incidence and Mortality in Malaysia. Open Forum Infectious Diseases 2017, 4: ofw219. PMID: 28480230, PMCID: PMC5414088, DOI: 10.1093/ofid/ofw219.Peer-Reviewed Original ResearchHuman immunodeficiency virusT-cell countsAdvanced human immunodeficiency virusAntiretroviral therapyKey risk populationsKey populationsRisk populationsEvidence-based treatment guidelinesHuman immunodeficiency virus (HIV) incidenceClinician-level interventionsHypothetical clinical scenariosProportion of physiciansHigher CD4HIV patientsPhysician adherenceControl patientsTreatment guidelinesHIV incidenceImmunodeficiency virusART accessART coverageInternet-based surveyPhysicians' attitudesPrevention strategiesClinical scenarios
2016
Confronting the HIV, Tuberculosis, Addiction, and Incarceration Syndemic in Southeast Asia: Lessons Learned from Malaysia
Culbert GJ, Pillai V, Bick J, Al-Darraji HA, Wickersham JA, Wegman MP, Bazazi AR, Ferro E, Copenhaver M, Kamarulzaman A, Altice FL. Confronting the HIV, Tuberculosis, Addiction, and Incarceration Syndemic in Southeast Asia: Lessons Learned from Malaysia. Journal Of Neuroimmune Pharmacology 2016, 11: 446-455. PMID: 27216260, PMCID: PMC5118227, DOI: 10.1007/s11481-016-9676-7.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyMalaysia's largest prisonIsoniazid preventive therapyLatent tuberculosis infectionStandardized treatment protocolMandatory HIV testingDrug treatment centersEvidence-based addiction treatmentEvidence-based interventionsLargest prisonReservoir of infectionActive diseaseActive tuberculosisPreventive therapyHIV testingTuberculosis infectionOpioid dependenceHIV treatmentRapid relapseMethadone maintenanceTreatment protocolClinical careHIVTreatment centersCompulsory drug treatment centers
2015
The syndemic of HIV, HIV-related risk and multiple co-morbidities among women who use drugs in Malaysia: Important targets for intervention
Loeliger KB, Marcus R, Wickersham JA, Pillai V, Kamarulzaman A, Altice FL. The syndemic of HIV, HIV-related risk and multiple co-morbidities among women who use drugs in Malaysia: Important targets for intervention. Addictive Behaviors 2015, 53: 31-39. PMID: 26436520, PMCID: PMC4679569, DOI: 10.1016/j.addbeh.2015.09.013.Peer-Reviewed Original ResearchConceptsDrug-using womenHIV testingFuture public health interventionsSubstance useHIV risk behaviorsSyndemics of HIVThird of womenPublic health problemInfrequent condom usePoor health outcomesHarm reduction effortsSubstance use disordersPublic health interventionsCross-sectional surveyUnstable living situationsSocial supportAntiretroviral therapyHIV prevalenceHIV transmissionHIV treatmentInjection paraphernaliaDrug injectionSocial comorbiditiesPsychiatric illnessMost womenBurden of substance use disorders, mental illness, and correlates of infectious diseases among soon-to-be released prisoners in Azerbaijan
Azbel L, Wickersham JA, Wegman MP, Polonsky M, Suleymanov M, Ismayilov R, Dvoryak S, Rotberga S, Altice FL. Burden of substance use disorders, mental illness, and correlates of infectious diseases among soon-to-be released prisoners in Azerbaijan. Drug And Alcohol Dependence 2015, 151: 68-75. PMID: 25861943, PMCID: PMC4447560, DOI: 10.1016/j.drugalcdep.2015.02.034.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyDrug injectionInfectious diseasesPrevalence of HCVSignificant independent correlatesLow HIV prevalenceHigh-endemic countriesHigh diagnostic rateEvidence-based addiction treatmentSubstance use disordersHealth assessment surveyHCV epidemicHepatitis BHCV diagnosisHIV statusHIV prevalenceART coverageHIV treatmentIndependent correlatesNew medicationsHIV epidemicHeterosexual riskHealth SurveyEndemic countriesHIV
2014
Correlates of HIV infection and being unaware of HIV status among soon‐to‐be‐released Ukrainian prisoners
Azbel L, Wickersham JA, Grishaev Y, Dvoryak S, Altice FL. Correlates of HIV infection and being unaware of HIV status among soon‐to‐be‐released Ukrainian prisoners. Journal Of The International AIDS Society 2014, 17: 19005. PMID: 25216073, PMCID: PMC4161962, DOI: 10.7448/ias.17.1.19005.Peer-Reviewed Original ResearchConceptsHIV infectionHIV testingHIV statusHIV epidemicDrug-related HIV risk behaviorsRisk-based HIV testingHIV risk behaviorsAntiretroviral therapyHIV-positiveHIV transmissionOpioid substitutionIndependent correlatesDrug injectionFemale genderHealth SurveySerological testingPrevious incarcerationRisk behaviorsDisproportionate burdenHIVInfectionEpidemicUkrainian prisonsCorrelatesStatus
2013
Alcohol use disorders and antiretroviral therapy among prisoners in Argentina
Alpert M, Wickersham JA, Vázquez M, Altice FL. Alcohol use disorders and antiretroviral therapy among prisoners in Argentina. International Journal Of Prisoner Health 2013, 9: 40-50. PMID: 24772187, PMCID: PMC3999974, DOI: 10.1108/17449201311310797.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAntiretroviral therapyUse disordersSecondary HIV preventionCent of subjectsCross-sectional surveyHIV careSubstance abuse patternsMajority of participantsIndependent correlatesHIV preventionTreatment outcomesGeneral populationHIVHealth care reformAbuse patternsAUDIT scaleCurrent incarcerationDisordersTherapyOne-thirdCare reformOne-quarterParticipantsFuture efforts
2011
Rationale, study design and sample characteristics of a randomized controlled trial of directly administered antiretroviral therapy for HIV-infected prisoners transitioning to the community — A potential conduit to improved HIV treatment outcomes
Saber-Tehrani AS, Springer SA, Qiu J, Herme M, Wickersham J, Altice FL. Rationale, study design and sample characteristics of a randomized controlled trial of directly administered antiretroviral therapy for HIV-infected prisoners transitioning to the community — A potential conduit to improved HIV treatment outcomes. Contemporary Clinical Trials 2011, 33: 436-444. PMID: 22101218, PMCID: PMC3268833, DOI: 10.1016/j.cct.2011.11.002.Peer-Reviewed Original ResearchConceptsHIV treatment outcomesSelf-administered therapyAntiretroviral therapyTreatment outcomesViral loadEvidence-based adherence interventionsPoor HIV treatment outcomesGenotypic resistance testingMedication-assisted treatmentDSM-IV criteriaAlcohol use disorderCase management servicesViral suppressionPrimary outcomeOpioid dependenceAdherence interventionsCD4 testingIntervention periodStudy groupEligibility criteriaUse disordersIntervention monthDrug usersAdverse HIVHIV