2020
Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision
Park SJ, Lieberman EE, Ke JB, Rho N, Ghorbani P, Rahmani P, Jun NY, Lee HL, Kim IJ, Briggman KL, Demb JB, Singer JH. Connectomic analysis reveals an interneuron with an integral role in the retinal circuit for night vision. ELife 2020, 9: e56077. PMID: 32412412, PMCID: PMC7228767, DOI: 10.7554/elife.56077.Peer-Reviewed Original ResearchConceptsAII amacrine cellsProjection neuronsSingle interneuron typeConnectomic analysisBipolar cell pathwaysNovel neural circuitGABAergic cellsAmacrine cellsCentral neuronsGanglion cellsSynaptic layersRetinal circuitsInterneuron typesSurround inhibitionMouse retinaNight visionON responseExcitatory centerOptogenetic analysesNeural circuitsInhibitory surroundCell pathwaysRod photoreceptorsReceptive fieldsRb pathway
2015
Function and Circuitry of VIP+ Interneurons in the Mouse Retina
Park SJ, Borghuis BG, Rahmani P, Zeng Q, Kim IJ, Demb JB. Function and Circuitry of VIP+ Interneurons in the Mouse Retina. Journal Of Neuroscience 2015, 35: 10685-10700. PMID: 26224854, PMCID: PMC4518048, DOI: 10.1523/jneurosci.0222-15.2015.Peer-Reviewed Original ResearchConceptsGanglion cell layerAmacrine cell typesInner nuclear layerAmacrine cellsGanglion cellsINL cellsON pathwayGanglion cell dendritesGanglion cell typesBipolar cell terminalsWhole-cell recordingsCell typesNervous system functionSpatial tuningBipolar cell pathwaysTransgenic mouse lineGCL cellsOptic nerveGABAergic interneuronsRetinal functionCell dendritesRetinal circuitryInhibitory interneuronsNuclear layerBipolar interneurons
2012
The most numerous ganglion cell type of the mouse retina is a selective feature detector
Zhang Y, Kim IJ, Sanes JR, Meister M. The most numerous ganglion cell type of the mouse retina is a selective feature detector. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: e2391-e2398. PMID: 22891316, PMCID: PMC3437843, DOI: 10.1073/pnas.1211547109.Peer-Reviewed Original ResearchConceptsGanglion cellsBipolar cellsMouse retinaW3 cellsGanglion cell typesRetinal ganglion cellsStrong lateral inhibitionReceptive field sizeDifferent visual inputsHuman retinaRetinaNeural imagesCell poolCommon visual stimuliReceptive fieldsVisual stimuliVisual inputCell typesUnusual conditionVisual sceneResponse propertiesCellsLateral inhibitionDistinct populationsNaturalistic stimuli