2023
Progress on the Endometrium
Frankfurter D, Kliman H. Progress on the Endometrium. Obstetrics And Gynecology Clinics Of North America 2023, 50: 677-694. PMID: 37914487, DOI: 10.1016/j.ogc.2023.09.002.Peer-Reviewed Original ResearchConceptsAbsence of pregnancyEvidence-based approachEndometrial assessmentStromal maturationEndometrial proliferationEndometrial pathologyInflammatory mediatorsOvarian steroidsImplantation failureBlastocyst implantationEndometrial sloughingDiagnostic measuresEndometriumOffer hopeDynamic tissueDevelopmental markersSingle testTissueInternal reproductionMaturationEndometriosisPregnancyDecidualizationInfertilityUterus
2022
X chromosome inactivation in the human placenta is patchy and distinct from adult tissues
Phung TN, Olney KC, Pinto BJ, Silasi M, Perley L, O’Bryan J, Kliman HJ, Wilson MA. X chromosome inactivation in the human placenta is patchy and distinct from adult tissues. Human Genetics And Genomics Advances 2022, 3: 100121. PMID: 35712697, PMCID: PMC9194956, DOI: 10.1016/j.xhgg.2022.100121.Peer-Reviewed Original ResearchX-chromosome inactivationAdult tissuesChromosome inactivationX chromosomeX chromosome expressionTissue-specific mapsPaternal X chromosomeHuman adult tissuesChromosome expressionX inactivationAllele-specific approachesGenetic femalesLarge patchesChromosomesHuman placentaInactivationTissueGenesRNADNAObserved sex differencesExpressionPlacenta
2019
Clinical approach to recurrent implantation failure: evidence-based evaluation of the endometrium
Kliman HJ, Frankfurter D. Clinical approach to recurrent implantation failure: evidence-based evaluation of the endometrium. Fertility And Sterility 2019, 111: 618-628. PMID: 30929719, DOI: 10.1016/j.fertnstert.2019.02.011.Peer-Reviewed Original ResearchConceptsRecurrent implantation failureImplantation failureHigh-quality embryosEvidence-based evaluationInflammatory markersRetained productsInflammatory lesionsHistologic evaluationQuality embryosClinical approachGrowth disordersActionable findingsEndometriumFunctional testsPatientsMolecular eraComplete assessmentTissueCycling tissueEndometrialFailureBest optionLesionsEvaluation