2024
Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration
Anderson G, Cook E, Blakely R, Sutcliffe J, Veenstra-VanderWeele J. Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration. Journal Of Inflammation Research 2024, 17: 2169-2172. PMID: 38628604, PMCID: PMC11019386, DOI: 10.2147/jir.s456000.Peer-Reviewed Original ResearchPlatelet serotoninSerotonin valuesTrials of SSRIsSerotonin reuptake inhibitorsPlatelet serotonin transportersSerotonin reductionSSRI administrationSSRI treatmentReuptake inhibitorsSerotonin transporterMemory impairmentSerotonin levelsSSRIsSerotoninDepletion of plateletsPlasma serotoninPeripheral serotoninSequelae of COVID-19Viremia patientsCardiovascular sequelaeCirculating serotoninHyperaggregable stateTreatment of COVID-19Clinical trialsLong COVID
1992
Double-Blind, Crossover Trial of Fluoxetine and Placebo in Children and Adolescents with Obsessive-Compulsive Disorder
RIDDLE M, SCAHILL L, KING R, HARDIN M, ANDERSON G, ORT S, SMITH J, LECKMAN J, COHEN D. Double-Blind, Crossover Trial of Fluoxetine and Placebo in Children and Adolescents with Obsessive-Compulsive Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 1992, 31: 1062-1069. PMID: 1429406, DOI: 10.1097/00004583-199211000-00011.Peer-Reviewed Original ResearchConceptsChildren's Yale-Brown Obsessive Compulsive ScaleObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleEffective short-term treatmentSafety of fluoxetineFixed-dose trialCommon drug side effectsCY-BOCS total scoreMajor depressive disorderShort-term treatmentDrug side effectsMagnitude of improvementObsessive Compulsive ScaleFluoxetine groupPlacebo groupFluoxetine treatmentCrossover trialClinical trialsDepressive disorderObsessive-compulsive symptom severitySide effectsFluoxetineSymptom severityTotal scoreCompulsive Scale
1983
Acute and Chronic CLonidine Treatment in Tourette's Syndrome A Preliminary Report on Clinical Response and Effect on Plasma and Urinary Catecholamine Metabolites, Growth Hormone, and Blood Pressure
LECKMAN J, DETLOR J, HARCHERIK D, YOUNG J, ANDERSON G, SHAYWITZ B, COHEN D. Acute and Chronic CLonidine Treatment in Tourette's Syndrome A Preliminary Report on Clinical Response and Effect on Plasma and Urinary Catecholamine Metabolites, Growth Hormone, and Blood Pressure. Journal Of The American Academy Of Child & Adolescent Psychiatry 1983, 22: 433-440. PMID: 6579101, DOI: 10.1016/s0002-7138(09)61504-1.Peer-Reviewed Original ResearchConceptsChronic clonidine treatmentClonidine treatmentTourette syndromeHomovanillic acidHuman growth hormoneClinical responseBlood pressureGrowth hormoneΑ2-adrenergic receptor agonistTreatment of TSUrinary catecholamine metabolitesClinical response dataChronic neuropsychiatric disorderPlacebo-controlled conditionsA Preliminary ReportClonidine therapyOral clonidineNoradrenergic receptorsSingle doseUnknown etiologyFunctional statusReceptor agonistClinical trialsDopaminergic systemTS patients