2024
F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING
Ito L, Ota V, Fernandes D, Martins A, Carvalho C, Zugman A, Sato J, Bressan R, Miguel E, Pan P, Salum G, Belangero S, Santoro M. F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING. European Neuropsychopharmacology 2024, 87: 214-215. DOI: 10.1016/j.euroneuro.2024.08.429.Peer-Reviewed Original ResearchPost-traumatic stress disorderAttention deficit/hyperactivity disorderBrain regionsBipolar disorderMental conditionBrain structuresBrazilian High-Risk Cohort StudyPrefrontal cortex regionsFrontal pole regionsHigh Risk Cohort StudyLateral orbitofrontal regionGenome-wide association studiesSignificant main effectDepressive disorderMixed-effects modelsStress disorderDeficit/hyperactivity disorderFrontal cortexOrbitofrontal regionsBiological underpinningsGenetic influencesCortex regionsLongitudinal relationshipIntracranial volumeEarly adulthood
2023
Alterations in microRNA of extracellular vesicles associated with major depression, attention-deficit/hyperactivity and anxiety disorders in adolescents
Honorato-Mauer J, Xavier G, Ota V, Chehimi S, Mafra F, Cuóco C, Ito L, Ormond R, Asprino P, Oliveira A, Bugiga A, Torrecilhas A, Bressan R, Manfro G, Miguel E, Rohde L, Pan P, Salum G, Pellegrino R, Belangero S, Santoro M. Alterations in microRNA of extracellular vesicles associated with major depression, attention-deficit/hyperactivity and anxiety disorders in adolescents. Translational Psychiatry 2023, 13: 47. PMID: 36746925, PMCID: PMC9902559, DOI: 10.1038/s41398-023-02326-4.Peer-Reviewed Original ResearchConceptsMental health disordersCross-sectional analysisMajor depressive disorderAttention-deficit/hyperactivity disorderHealth disordersAnxiety disordersExtracellular vesiclesLarge ongoing cohort studiesMiR-432-5pPeripheral extracellular vesiclesTime pointsOngoing cohort studyMiR-328-3pSerum extracellular vesiclesLongitudinal analysisWave 2Deficit/hyperactivity disorderAdolescent participantsTotal extracellular vesiclesAttention-deficit/hyperactivityMiRNA expressionCohort studyDepressive disorderMajor depressionMiR-584-5p
2012
Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study
Torres A, Fontenelle L, Ferrão Y, do Rosário M, Torresan R, Miguel E, Shavitt R. Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study. Journal Of Psychiatric Research 2012, 46: 724-732. PMID: 22464941, DOI: 10.1016/j.jpsychires.2012.03.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresOCD patientsLogistic regressionDSM-IV OCD patientsCertain clinical featuresCross-sectional studyAttention-deficit/hyperactivity disorderStatistical univariate analysisBrazilian Research ConsortiumDeficit/hyperactivity disorderHigher anxiety scoresYale-Brown ObsessiveSymptom onsetInsidious onsetMulticenter studyObsessive-compulsive spectrum disordersSectional studyPossible confoundersUnivariate analysisTic disordersHoarding dimensionPatientsSymptomsPoor insight