F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING
Ito L, Ota V, Fernandes D, Martins A, Carvalho C, Zugman A, Sato J, Bressan R, Miguel E, Pan P, Salum G, Belangero S, Santoro M. F18. ROLE OF PSYCHIATRIC-ASSOCIATED SNVS IN THE EARLY ADULTHOOD: INSIGHTS FROM LONGITUDINAL NEUROIMAGING. European Neuropsychopharmacology 2024, 87: 214-215. DOI: 10.1016/j.euroneuro.2024.08.429.Peer-Reviewed Original ResearchPost-traumatic stress disorderAttention deficit/hyperactivity disorderBrain regionsBipolar disorderMental conditionBrain structuresBrazilian High-Risk Cohort StudyPrefrontal cortex regionsFrontal pole regionsHigh Risk Cohort StudyLateral orbitofrontal regionGenome-wide association studiesSignificant main effectDepressive disorderMixed-effects modelsStress disorderDeficit/hyperactivity disorderFrontal cortexOrbitofrontal regionsBiological underpinningsGenetic influencesCortex regionsLongitudinal relationshipIntracranial volumeEarly adulthoodGPT-based normative models of brain sMRI correlate with dimensional psychopathology
Mendes S, Pinaya W, Pan P, Gadelha A, Belangero S, Jackowski A, Rohde L, Miguel E, Sato J. GPT-based normative models of brain sMRI correlate with dimensional psychopathology. Imaging Neuroscience 2024, 2: 1-15. DOI: 10.1162/imag_a_00204.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderChild Behavior ChecklistDeficit hyperactivity disorderAutism spectrum disorderPsychiatric disordersBrain regionsStructural MRIDimensional psychopathologyHyperactivity disorderBrazilian High-Risk Cohort StudyAttention deficit hyperactivity disorder scoresAutism Brain Imaging Data Exchange IIAdolescent Brain Cognitive DevelopmentChild Behavior Checklist scalesHigh Risk Cohort StudyDetect psychiatric symptomsEmergent psychiatric disordersBrain structural MRINeurobiological substratesNeuroimaging studiesLanguage tasksPsychiatric symptomsBehavior ChecklistPsychiatric conditionsSpectrum disorder