2024
Long-Term Outcomes of Patients With Apical Hypertrophic Cardiomyopathy Utilizing a New Risk Score
Hajj-Ali A, Gaballa A, Akintoye E, Jadam S, Ramchand J, Xu B, Ospina S, Thamilarasan M, Smedira N, Popovic Z, Desai M. Long-Term Outcomes of Patients With Apical Hypertrophic Cardiomyopathy Utilizing a New Risk Score. JACC Advances 2024, 3: 101235. PMID: 39512540, PMCID: PMC11540864, DOI: 10.1016/j.jacadv.2024.101235.Peer-Reviewed Original ResearchApical hypertrophic cardiomyopathyRight ventricular systolic pressureLeft atrial volume indexAtrial volume indexVentricular systolic pressureRisk scoreApical aneurysmEnd pointsHypertrophic cardiomyopathyMean left ventricle ejection fractionSystolic pressureLong-term outcomes of patientsApical hypertrophic cardiomyopathy patientsVolume indexBaseline cardiac magnetic resonanceComposite primary end pointPrimary end pointOutcomes of patientsVentricle ejection fractionDelayed gadolinium enhancementCardiac magnetic resonanceComposite end pointLong-term outcomesComposite event rateLeft ventricle apexLongitudinal Assessment of Left Atrial Remodeling in Patients With Chronic Severe Aortic Regurgitation
Akintoye E, El Dahdah J, Dabbagh M, Patel H, Badwan O, Braghieri L, Chedid El Helou M, Kassab J, Jellis C, Desai M, Rodriguez L, Grimm R, Roselli E, Griffin B, Popovic Z. Longitudinal Assessment of Left Atrial Remodeling in Patients With Chronic Severe Aortic Regurgitation. JACC Cardiovascular Imaging 2024, 17: 1133-1145. PMID: 38878040, DOI: 10.1016/j.jcmg.2024.04.007.Peer-Reviewed Original ResearchLeft atrial volume indexLeft atrial reservoir strainAortic regurgitationLV parametersAssociated with survival benefitMedian follow-up periodChronic severe aortic regurgitationLeft ventricular (LVShort-term follow-upOptimal discriminatory thresholdsSevere aortic regurgitationAtrial volume indexIncremental prognostic valueAtrial reservoir strainLeft atrial remodelingFollow-up periodAssociated with survivalPredicting adverse eventsReservoir strainSerial echocardiographySevere ARSurvival benefitLA remodelingLV remodelingPrognostic value
2017
Role of diastolic function indices in the risk stratification of patients with mixed aortic valve disease
Egbe A, Khan A, Boler A, Said S, Geske J, Miranda W, Akintoye E, Connolly H, Warnes C, Oh J. Role of diastolic function indices in the risk stratification of patients with mixed aortic valve disease. European Heart Journal - Cardiovascular Imaging 2017, 19: 668-674. PMID: 28655164, DOI: 10.1093/ehjci/jex148.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnalysis of VarianceAortic Valve InsufficiencyAortic Valve StenosisAsymptomatic DiseasesCohort StudiesConfidence IntervalsDiastoleEchocardiographyFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentSex FactorsStroke VolumeSurvival RateUnited StatesConceptsAortic valve replacementCardiovascular adverse eventsRelative wall thicknessMixed aortic valve diseaseDiastolic function indicesAortic valve diseaseCardiac deathRisk stratificationValve diseaseFunction IndexHigh-risk patient subsetsPost-operative risk stratificationSevere left ventricular dysfunctionAtrial volume indexHeart failure hospitalizationTricuspid regurgitation velocityEarly diastolic velocityLeft ventricular dysfunctionMultivariable risk factorsAsymptomatic patientsCardiovascular morbidityFailure hospitalizationPrimary endpointSecondary endpointsVentricular dysfunction