2024
Integrated stepped alcohol treatment with contingency management for unhealthy alcohol use among people with HIV: A randomized controlled trial.
Edelman E, Dziura J, Deng Y, DePhilippis D, Ferguson T, Brown S, Marconi V, Goetz M, Rodriguez-Barradas M, Simberkoff M, Molina P, Weintrob A, Maisto S, Paris M, Justice A, Bryant K, Fiellin D. Integrated stepped alcohol treatment with contingency management for unhealthy alcohol use among people with HIV: A randomized controlled trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024 PMID: 39321757, DOI: 10.1097/qai.0000000000003534.Peer-Reviewed Original ResearchUnhealthy alcohol useSelf-reported abstinenceAlcohol useLost to follow-upContingency managementAlcohol use disorderRandomized controlled trialsSubstance use treatmentAlcohol abstinenceFollow-upUse disorderControlled trialsPWHAlcohol treatmentAbstinenceUse treatmentEvidence of abstinenceHIVWeeksMean proportionTreatmentTrialsAlcoholDaysParticipants
2023
Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17
Heimer R, Black A, Lin H, Grau L, Fiellin D, Howell B, Hawk K, D'Onofrio G, Becker W. Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17. Drug And Alcohol Dependence 2023, 254: 111040. PMID: 38043226, PMCID: PMC10872282, DOI: 10.1016/j.drugalcdep.2023.111040.Peer-Reviewed Original ResearchConceptsNon-medication treatmentsRelative riskOpioid overdose deathsIncidence rateMOUD treatmentOverdose deathsOpioid use disorder treatmentResults Incidence ratesRetrospective cohort studyDifferent treatment modalitiesPopulation-level effortsUse disorder treatmentFatal opioid poisoningsCohort studyOpioid poisoningTreatment modalitiesConclusion ExposurePoisoning deathsFatal overdosesTreatment exposureDisorder treatmentDeathTreatmentMethadoneRiskLong-Term Treatment of Opioid Use Disorder with Medications
Wolfgang A, Weimer M, Na P, Fiellin D, Muvvala S. Long-Term Treatment of Opioid Use Disorder with Medications. 2023, 631-661. DOI: 10.1093/oxfordhb/9780197618431.013.23.ChaptersOpioid use disorderMedical diseasesUse disordersChronic medical diseasesExtended-release naltrexoneLong-term treatmentCause mortalityOUD treatmentClinical outcomesOngoing treatmentOpioid overdoseTerm treatmentMedicationsPsychosocial outcomesAddiction treatmentDisease paradigmOutcomesTreatmentEvidence-based paradigmDiseaseDisordersNegative outcomesImproved retentionRemissionRelapsingFacilitation and Preferred Models for Delivering Substance Use Disorder Treatment in HIV Clinics: Results From a Multisite Randomized Trial
Muvvala S, Gan G, Morford K, Dziura J, Esserman D, Porter E, Chan P, Cornman D, Reynolds J, Yager J, Fiellin D, Edelman E. Facilitation and Preferred Models for Delivering Substance Use Disorder Treatment in HIV Clinics: Results From a Multisite Randomized Trial. Journal Of Addiction Medicine 2023, 17: e388-e391. PMID: 37934538, PMCID: PMC10726383, DOI: 10.1097/adm.0000000000001192.Peer-Reviewed Original ResearchConceptsOpioid use disorderAlcohol use disorderTobacco use disorderHIV clinicUse disordersAddiction treatmentSubstance use disorder treatmentUse disorder treatmentMaintenance phaseRandomized trialsStaff preferencesImproved outcomesMultisite Randomized TrialImplementation facilitationDisorder treatmentControl phaseClinicCliniciansTreatment modelTreatmentDisordersSignificant differencesInterventionHigher proportionAddiction treatment models
2013
Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence
Alford D, Barry D, Fiellin D. Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence. 2013, 31-37. DOI: 10.1007/978-1-4614-6974-2_3.ChaptersPain complaintsOpioid dependenceMethadone maintenanceChronic painOpioid-dependent patientsIllicit opioid useTreatment of painOpioid usePrescription opioidsMaintenance treatmentPain perceptionClinical challengePainPsychiatric disordersPatientsMethadonePhysiologic toleranceEffective coping skillsComplaintsOpioidsMedicationsTreatmentCoping skillsLoss of controlAddiction
2008
Narrative review: buprenorphine for opioid-dependent patients in office practice.
Sullivan LE, Fiellin DA. Narrative review: buprenorphine for opioid-dependent patients in office practice. Annals Of Internal Medicine 2008, 148: 662-70. PMID: 18458279, PMCID: PMC3694223, DOI: 10.7326/0003-4819-148-9-200805060-00006.Peer-Reviewed Original ResearchConceptsOpioid dependencePrescription opioidsPartial opioid agonistOpioid-dependent patientsOpioid-dependent personsUse of buprenorphineOffice-based treatmentBuprenorphine-naloxone combinationClinical presentationIllicit opioidsOpioid agonistsPatient populationOpioidsBuprenorphineOffice practicePatientsTreatmentRecent dataPhysiciansAbuseAgonistsPrevalenceHeroin
2006
Training HIV Physicians to Prescribe Buprenorphine for Opioid Dependence
Sullivan LE, Tetrault J, Bangalore D, Fiellin DA. Training HIV Physicians to Prescribe Buprenorphine for Opioid Dependence. Substance Abuse 2006, 27: 13-18. PMID: 17135176, DOI: 10.1300/j465v27n03_03.Peer-Reviewed Original Research
2005
Faculty Development in Small-Group Teaching Skills Associated with a Training Course on Office-Based Treatment of Opioid Dependence
Wong JG, Holmboe ES, Becker W, Fiellin D, Jara G, Martin J. Faculty Development in Small-Group Teaching Skills Associated with a Training Course on Office-Based Treatment of Opioid Dependence. Substance Abuse 2005, 25: 35-40. PMID: 16172091, DOI: 10.1300/j465v25n04_05.Peer-Reviewed Original ResearchConceptsOpioid dependenceDrug Addiction Treatment ActOffice-Based TreatmentOpioid-dependent patientsOpioid treatment programsTreatment programQualified physiciansScore responsesSchedule IIITreatment ActDATADescriptive questionnairePhysiciansTraining sessionsTreatmentPatient case discussionsSignificant improvementFacilitatorsSessionsMedicationsBuprenorphinePatients
2002
New federal initiatives to enhance the medical treatment of opioid dependence.
Fiellin DA, O'Connor PG. New federal initiatives to enhance the medical treatment of opioid dependence. Annals Of Internal Medicine 2002, 137: 688-92. PMID: 12379070, DOI: 10.7326/0003-4819-137-8-200210150-00014.Peer-Reviewed Original ResearchConceptsOpioid dependenceMedical treatmentOpioid agonist medicationsRole of internistsAgonist medicationsPharmacologic treatmentMaintenance treatmentNew medicationsMedical conditionsOffice settingSubstantial healthMedicationsPatientsTreatmentInternistsRecent federal initiativesFederal initiativesNew federal initiativesComplicationsCare
2001
INNOVATIONS IN TREATMENT FOR DRUG ABUSE: Solutions to a Public Health Problem
Sindelar J, Fiellin D. INNOVATIONS IN TREATMENT FOR DRUG ABUSE: Solutions to a Public Health Problem. Annual Review Of Public Health 2001, 22: 249-272. PMID: 11274521, DOI: 10.1146/annurev.publhealth.22.1.249.ChaptersConceptsPublic health problemEffectiveness of treatmentIllicit drug useDrug useHealth problemsDrug dependenceBroader social costsImportant public health problemNew pharmacological agentsFuture treatment programsIndividual functioningStandard treatmentPharmacological agentsTreatment programDrug abuseCounseling strategiesPrevention effortsHigh dropout rateTreatmentFunctioningCompletion ratesDropout rateLow completion ratesLow effectivenessNew setting
2000
Pharmacologic treatment of heroin-dependent patients.
O'Connor P, Fiellin D. Pharmacologic treatment of heroin-dependent patients. Annals Of Internal Medicine 2000, 133: 40-54. PMID: 10877739, DOI: 10.7326/0003-4819-133-1-200007040-00008.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHeroin dependenceHeroin-dependent patientsDrug treatment settingsBehavioral health problemsOpioid withdrawalPharmacologic treatmentMethadone maintenanceHeroin usePhysician's officeTreatment approachesTreatment settingsHealth problemsPatientsRelapse preventionTreatmentPhysiciansAcetylmethadolBuprenorphineInternistsReferralDiagnosisAlternative sitesPrevention