2024
Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules
Spaulding S, Maayah M, Dinauer C, Prasad M, Darbinyan A, Morotti R, Christison-Lagay E. Molecular Genetics Augment Cytopathologic Evaluation and Surgical Planning of Pediatric Thyroid Nodules. Journal Of Pediatric Surgery 2024, 59: 975-980. PMID: 38246817, DOI: 10.1016/j.jpedsurg.2024.01.001.Peer-Reviewed Original ResearchFine-needle aspiration biopsyPediatric thyroid nodulesMolecular genetic testingBethesda IV nodulesPrediction of malignancyDICER1 mutationsThyroid nodulesGenetic testingNRAS mutationsMethods Retrospective chart reviewRetrospective chart reviewTime of surgeryBRAF V600E testingMutations/fusionsBethesda III nodulesChart reviewSurgical resectionFinal histopathologyThyroid resectionPediatric dataHistologic classificationSurgical specimensBRAF mutationsAspiration biopsyCytopathologic evaluation
2022
Differences in the management of thyroid nodules in children and adolescents as compared to adults
Goldfarb M, Dinauer C. Differences in the management of thyroid nodules in children and adolescents as compared to adults. Current Opinion In Endocrinology Diabetes And Obesity 2022, 29: 466-473. PMID: 35777975, DOI: 10.1097/med.0000000000000754.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPediatric thyroid nodulesThyroid nodulesFine-needle aspiration biopsyRisk of malignancyRisk stratification systemSpecific risk factorsAppropriate imaging modalityNeedle aspiration biopsyCertain genetic syndromesYounger patientsNonoperative approachClinical managementRadiofrequency ablationRisk factorsPretest probabilityAspiration biopsyMiRNA classifierSpecific molecular testsMolecular testingUltrasound characteristicsAge groupsGenetic syndromesClinical usePatientsBenign nodules
2019
Malignancy Rates in Cytologically Indeterminate Thyroid Nodules among Children Are Lower Than Previously Reported but Remain Higher Than in Adults
Dinauer C. Malignancy Rates in Cytologically Indeterminate Thyroid Nodules among Children Are Lower Than Previously Reported but Remain Higher Than in Adults. Clinical Thyroidology 2019, 31: 158-161. DOI: 10.1089/ct.2019;31.158-161.Commentaries, Editorials and Letters
2017
The Pediatric Thyroid Nodule and Papillary Thyroid Cancer Management
Rivkees S, Dinauer C. The Pediatric Thyroid Nodule and Papillary Thyroid Cancer Management. 2017, 199-216. DOI: 10.1007/978-3-319-43618-0_13.ChaptersDifferentiated thyroid cancerPediatric thyroid cancerThyroid cancerPediatric differentiated thyroid cancerPediatric thyroid nodulesRisk of recurrenceThyroid cancer managementHigh recurrence rateBest care optionsDTC managementInitial therapyExcellent prognosisProspective trialRandomized trialsRecurrence ratePotential complicationsTreatment recommendationsCancer managementHigh incidenceRare diseaseTreatment approachesAdvanced stageUncommon occurrenceCare optionsThyroid nodules
2015
Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer
Francis GL, Waguespack SG, Bauer AJ, Angelos P, Benvenga S, Cerutti JM, Dinauer CA, Hamilton J, Hay ID, Luster M, Parisi MT, Rachmiel M, Thompson GB, Yamashita S. Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid 2015, 25: 716-759. PMID: 25900731, PMCID: PMC4854274, DOI: 10.1089/thy.2014.0460.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDifferentiated thyroid cancerAmerican Thyroid AssociationThyroid cancerThyroid nodulesUnited States Preventive Services Task ForceFine needle aspiration cytologyRadioactive iodine therapyLong-term outcomesManagement of childrenFollicular thyroid cancerTask ForceScientific evidenceYears of ageLong-term harmIodine therapyPostoperative stagingAggressive treatmentThyrotropin suppressionClinical presentationPreoperative stagingSurgical managementOptimal careThyroid AssociationAspiration cytologyHigh risk