2024
Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up
Dietz N, Kumar C, Elsamadicy A, Bjurström M, Wong K, Jamieson A, Sharma M, Wang D, Ugiliweneza B, Drazin D, Boakye M. Polypharmacy in elective lumbar spinal surgery for degenerative conditions with 24-month follow-up. Scientific Reports 2024, 14: 25340. PMID: 39455709, PMCID: PMC11511981, DOI: 10.1038/s41598-024-76248-6.Peer-Reviewed Original ResearchConceptsDegenerative lumbar pathologySurgical site infectionSpinal surgeryPolypharmacy groupSite infectionLumbar pathologyFollow-upMedical complicationsElective lumbar spinal surgeryLumbar spinal surgeryUrinary tract infectionDegenerative lumbar conditionsReturn to the emergency departmentTract infectionsNon-polypharmacy groupSurgical patientsLumbar conditionsSurgeryPatientsComplicationsPolypharmacyEmergency departmentPrescribed medicationsMarketScan datasetDegenerative conditionsThe Impact of Preoperative Spinal Injection Timing on the Postoperative Complications of Lumbar Fusion
Mirpuri P, Khalid S, Colliander R, King P, Tao X, Elsamadicy A, Mehta A, Adogwa O. The Impact of Preoperative Spinal Injection Timing on the Postoperative Complications of Lumbar Fusion. World Neurosurgery 2024, 190: e121-e128. PMID: 39002778, DOI: 10.1016/j.wneu.2024.07.050.Peer-Reviewed Original ResearchTransforaminal lumbar interbody fusionCSF leakSurgical complicationsComplication rateIncidence of CSF leakRate of CSF leakSecondary outcomesRate of surgical complicationsSurgical complication ratePostoperative surgical complicationsSurgical site infectionDay of surgeryLumbar interbody fusionPostoperative complicationsSite infectionWound disruptionPostoperative rateAdult patientsLumbar fusionInterbody fusionIncreased riskPrimary outcomePatientsSurgeryPrimary analysis
2023
Outcomes Following 2-Level Cervical Interventions with Cage-and-Plate, Zero-Profile, or Arthroplasty Constructs
Khalid S, Mirpuri P, Thomson K, Elsamadicy A, Massaad E, Deysher D, Khilwani H, Adogwa O, Shin J, Mehta A. Outcomes Following 2-Level Cervical Interventions with Cage-and-Plate, Zero-Profile, or Arthroplasty Constructs. World Neurosurgery 2023, 180: e607-e617. PMID: 37797683, DOI: 10.1016/j.wneu.2023.09.117.Peer-Reviewed Original ResearchConceptsAdditional surgeryCervical interventionsPlate constructZero-profileMedical complicationsAnterior cervical proceduresDisc height restorationPostoperative medical complicationsOutcomes of patientsCervical disc diseaseLogistic regression modelsCervical proceduresSecondary outcomesSurgical complicationsIndex interventionPrimary outcomeIndex procedureHeight restorationDisc diseasePatientsSurgeryArthroplastyMotion limitationArtificial discComplicationsAssessment of the impact of frailty on adverse surgical outcomes in patients undergoing surgery for intracranial tumors using modified frailty index: A systematic review and meta-analysis
Aghajanian S, Shafiee A, Ahmadi A, Elsamadicy A. Assessment of the impact of frailty on adverse surgical outcomes in patients undergoing surgery for intracranial tumors using modified frailty index: A systematic review and meta-analysis. Journal Of Clinical Neuroscience 2023, 114: 120-128. PMID: 37390775, DOI: 10.1016/j.jocn.2023.06.013.Peer-Reviewed Original ResearchConceptsImpact of frailtyFrailty indexMFI scoreAdverse outcomesReoperation rateIntracranial tumorsNon-frail participantsAdverse surgical outcomesNeuro-oncological surgeryWeb of SciencePerioperative outcomesComplication rateIndependent predictorsSurgical outcomesWorse prognosisMean ageObservational studySurgical pathologyMixed-effects multilevel modelsPrimary analysisSystematic reviewNeurosurgical proceduresFrailtySurgical operationSurgeryIn Reply to the Letter to Editor Regarding "Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus"
Koo A, Elsamadicy A, Matouk C. In Reply to the Letter to Editor Regarding "Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus". World Neurosurgery 2023, 169: 124. PMID: 36585096, DOI: 10.1016/j.wneu.2022.11.023.Peer-Reviewed Original Research
2022
Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty
Elsamadicy A, Koo A, Reeves B, Cross J, Hersh A, Hengartner A, Karhade A, Pennington Z, Akinduro O, Lo S, Gokaslan Z, Shin J, Mendel E, Sciubba D. Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty. Global Spine Journal 2022, 14: 1227-1237. PMID: 36318478, PMCID: PMC11289550, DOI: 10.1177/21925682221138053.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreSpinal column tumorsFrailty Risk ScoreInfluence of frailtySpinal column metastasesProportion of patientsRetrospective cohort studyNationwide Readmissions DatabaseRisk of readmissionMultivariate regression analysisIntermediate frailtyAdult patientsCohort studyIndependent predictorsSurgical interventionSpine surgeryReadmissionPatient readmissionRisk scorePatientsFrailtySurgeryCohortTumorsRegression analysisResponse: Implications of HFRS in Patients Undergoing Surgery for Primary Spinal Intradural/Cord Tumors
Elsamadicy A, Koo A, Sciubba D. Response: Implications of HFRS in Patients Undergoing Surgery for Primary Spinal Intradural/Cord Tumors. Global Spine Journal 2022, 13: 256-256. PMID: 36154494, PMCID: PMC9837522, DOI: 10.1177/21925682221129552.Peer-Reviewed Original Research
2020
Geographic Variation in Outcomes and Costs After Spinal Fusion for Adolescent Idiopathic Scoliosis
Koo AB, Elsamadicy AA, Kundishora AJ, David WB, Lee M, Hong CS, Lee V, Kahle KT, DiLuna M. Geographic Variation in Outcomes and Costs After Spinal Fusion for Adolescent Idiopathic Scoliosis. World Neurosurgery 2020, 136: e347-e354. PMID: 31917315, DOI: 10.1016/j.wneu.2019.12.175.Peer-Reviewed Original ResearchConceptsAdolescent idiopathic scoliosisLength of surgeryAdolescent patientsSpinal fusionIdiopathic scoliosisMultilevel posterior spinal fusionHealth care resource utilizationGreater complication ratePosterior spinal fusionPosterior spinal surgeryPostoperative complicationsComplication ratePrimary outcomeAIS patientsSpinal surgeryPatientsSurgeryAdmissionRegional variationComplicationsFurther studiesOutcomesCohortScoliosisTotal cost
2018
Socioeconomic Factors, Perioperative Complications, and 30-Day Readmission Rates Associated With Delayed Cranial Vault Reconstruction for Craniosynostosis
Sergesketter AR, Elsamadicy AA, Lubkin DT, Kemeny H, Harward SC, Krucoff KB, Krucoff MO, Fuchs H, Thompson EM, Allori AC, Marcus JR, Muh CR. Socioeconomic Factors, Perioperative Complications, and 30-Day Readmission Rates Associated With Delayed Cranial Vault Reconstruction for Craniosynostosis. Journal Of Craniofacial Surgery 2018, 29: 1767-1771. PMID: 30059426, DOI: 10.1097/scs.0000000000004787.Peer-Reviewed Original ResearchMeSH KeywordsChild, PreschoolCraniosynostosesDevelopmental DisabilitiesFemaleHealthcare DisparitiesHumansIncidenceInfantIntracranial HypertensionLanguageMalePatient ReadmissionPlastic Surgery ProceduresPostoperative ComplicationsRacial GroupsRetrospective StudiesRisk FactorsSkullSocioeconomic FactorsTime-to-TreatmentConceptsCranial vault reconstructionNon-English primary languageReadmission ratesMonths of ageMedicaid insurancePrimary cranial vault reconstructionCraniosynostosis patientsPerioperative complication ratePerioperative complicationsPrimary surgeryPatient demographicsComplication ratePatient barriersMedical recordsFirst consultIntracranial pressureSurgeryPatientsEsthetic consequencesPrimary languagePremature fusionDevelopmental disabilitiesSocioeconomic factorsComplicationsChildren
2017
Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity
Adogwa O, Elsamadicy AA, Sergesketter A, Vuong VD, Moreno J, Cheng J, Karikari IO, Bagley CA. Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity. World Neurosurgery 2017, 110: e67-e72. PMID: 29081391, DOI: 10.1016/j.wneu.2017.10.081.Peer-Reviewed Original ResearchConceptsNormal cognitive statusCognitive impairmentCognitive statusOlder patientsSLUMS scorePreoperative cognitive impairmentElective spinal surgeryPreoperative cognitive statusStandard deviation ageAdult degenerative scoliosisBaseline cognitive impairmentSevere cognitive impairmentMental status testsMild cognitive impairmentPostoperative lengthPreoperative scoresDeviation ageGeriatric patientsDegenerative scoliosisIndependent associationSpinal surgeryDeformity correctionPatientsSurgeryCognitive screening